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Vertipro (Prochlorperazine)

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Vertipro is a piperazine phenothiazine and first-generation antipsychotic drug that is used for the treatment of severe nausea and vomiting, as well as short-term management of psychotic disorders such as generalized non-psychotic anxiety and schizophrenia.

Other names for this medication:
Bukatel, Compro, Emidoxyn, Eminorm, Ingametil, Meditil, Neurocin, Neurograin, Neurolice, Neuromol, Neuronit, Novapar, Nuroflow, Nuropar, Prochlorperazine, Procomp, Psygrain, Stemetil, Swigrain, Vasograin, Vertipro, Vestil

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Also known as: Prochlorperazine


Prochlorperazine suppository is used to control severe nausea and vomiting. This medicine should not be used to treat behavioral problems in older adult patients who have dementia.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain prochlorperazine. It may not be specific to Vertipro. Please read with care.

Use this medicine exactly as directed by your doctor. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered.

Do not take rectal suppositories by mouth or use it in the vagina.

To use the suppository:

If the suppository is too soft to insert, chill it in the refrigerator for 20 to 30 minutes or run cold water over it before removing the wrapper. Remove the wrapper and moisten the suppository with cool water. Lie down on your side and use your finger to push the suppository well up into the rectum. Make sure to wash your hands with soap and water before and after using this medicine.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For rectal dosage form (suppository): For severe nausea and vomiting: Adults—25 milligrams (mg) 2 times a day. Children—Use and dose must be determined by your doctor.


If you overdose Generic Vertipro and you don't feel good you should visit your doctor or health care provider immediately.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Vertipro are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Generic Vertipro if you are allergic to Generic Vertipro components. Do not take Generic Vertipro if you're pregnant or you plan to have a baby, or you are a nursing mother. Do not take Generic Vertipro if you are taking astemizole, cisapride, or terfenadine. Do not take Generic Vertipro if you have severe central nervous system depression. Be careful with Generic Vertipro if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement. Be careful with Generic Vertipro if you have a history of heart disease, central nervous system depression, blood problems, liver problems, low blood pressure, increased pressure in the eye, neuroleptic malignant syndrome, tardive dyskinesia, bone marrow problems, unusual muscle movements, Parkinson disease, a predisposition to glaucoma, Reye syndrome, prostate problems, or seizures, or you have alcoholism. Be careful with Generic Vertipro if you are taking anticholinergics (eg, diphenhydramine, oxybutynin, scopolamine) or lithium because they may decrease Generic Vertipro 's effectiveness; angiotensin-converting enzyme (ACE) inhibitors (eg, enalapril), anticholinergics (eg, diphenhydramine, oxybutynin, scopolamine), general anesthetics (eg, thiopental), haloperidol, methyldopa, or tricyclic antidepressants (eg, amitriptyline) because the risk of side effects, such as seizures, may be increased; ACE inhibitors (eg, enalapril), anticholinergics (eg, diphenhydramine, oxybutynin, scopolamine), astemizole, cisapride, dofetilide, haloperidol, hydantoins (eg, phenytoin), methyldopa, metrizamide, naltrexone, polypeptide antibiotics (eg, actinomycin), serotonin receptor antagonist antiemetics (eg, ondansetron), terfenadine, tramadol, trazodone, or tricyclic antidepressants (eg, amitriptyline) because the risk of their side effects may be increased by Generic Vertipro; bromocriptine, guanethidine, levodopa, or pergolide because their effectiveness may be decreased by Generic Vertipro; lithium because unexpected toxic effects may occur. Avoid alcohol. Do not stop taking Generic Vertipro suddenly.

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Most modern medication against osteoporosis has documented effect first and foremost against vertebral fractures. Alterations in the rat renal glycosaminoglycans in streptozotocin-induced diabetes. Effect of intravenous infusion on development of pulmonary oedema after inhalation injury. A protein with endochitinase activity was isolated and purified from the supernatant fluid by concentration, precipitation, hydrophobic interaction, gel filtration and adsorption procedures. This E/I imbalance seems to be correlated with alterations in the plasticity of interneurons but there is still scarce information on the mechanisms that may link these phenomena. The apoptotic and autophagic properties of two natural occurring prodrugs, hyperoside and hypoxoside, against pancreatic cancer cell lines.

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A total of 15 wild-type Brocothrix thermosphacta strains isolated from beef and the type strain, B. Co-localization between cGMP and the vesicular acetylcholine transporter was only observed to a minor degree in the ventral forebrain, the hippocampus, the reticular thalamic nucleus, and the nucleus ambiguus. Proprotein Convertase Subtilisin/Kexin type 9 (PCSK9): Impact of PCSK9 on Major Adverse Cardiac and Cerebrovascular Events. This approach has utility in areas such as modeling protein/protein interactions and designing fluorescence energy transfer assays.Using the crystallographic data for papain (monovalent ligand ) and concanavalin A (monovalent receptor ) along with a molecular graphics computational package the ligand and receptor were docked together to form a ligand/receptor complex. Analytical chemistry has changed considerably, driven by automation, miniaturization, and system integration with high throughput for multiple tasks. However, studies have largely examined neuropsychological functioning in patients during the symptomatic phase.

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GLUCOSE-6-PHOSPHATE DEHYDROGENASE, COLOUR VISION AND XG BLOOD GROUPS IN GREECE: LINKAGE AND POPULATION DATA. Health care personnel treating victims of politically motivated violence are at risk for traumatic stress symptoms. The molecular-cytogenetic characterization of a de novo pure partial trisomy 10(q24.33-qter) is described. Patients were evaluated at 6-month intervals for 2 years with right heart catheterization, radionuclide scans, echocardiography, as well as questionnaires for assessing quality of life. Oxygen consumption was measured and caloric expenditure calculated (indirect calorimetry) in ten adult patients with acute renal failure (ARF) following surgery. Prenatal diagnosis and postnatal follow-up of pericallosal lipoma: report of seven new cases. Activation of group IV afferent units from muscle by algesic agents. Amyloid degeneration in the light of clinical and experimental studies.

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Incorporating Cl- results in the lattice contracting gradually along with c-axis. Our analysis of 11 genetic markers was based on the hypothesis that the chromosome initiated replication at a fixed origin and proceeded in a linear fashion to the terminus. Resistant esophageal stenosis associated with reflux after repair of esophageal atresia: a therapeutic approach. Further, immobilization of the reconstituted enzyme by use of ENT prepolymer resulted in a high activity, whereas no remarkable activity was detected with the immobilized enzyme without reconstitution. Selectivity enhancement of an Escherichia coli bacterial electrode using enzyme and transport inhibitors. The influencing factors on suicide attempt among adolescents in South Korea.

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Concomitant field terms for asymmetric gradient coils: consequences for diffusion, flow, and echo-planar imaging. A longitudinal analysis of the impact of hospital service line profitability on the likelihood of readmission. Given the high cost of treatment, dynamic testing for growth hormone deficiency should only be performed in patients in whom there is high clinical suspicion, and therapy should be limited to those with biochemically proven growth hormone deficiency. Spectrin functions as a tetramer consisting of two heterodimers each containing two subunits termed alpha and beta. EFFECT OF THE MILITARY MEDICAL SERVICE ON THE DEVELOPMENT OF THE PUBLIC HEALTH SERVICE IN SURINAM. However, our knowledge about phosphatases lags well behind that of kinases. We found that several yeast introns function to repress rather than to increase steady-state mRNA levels. Plasma PCSK9 concentrations were increased dose dependently in mice injected with AAV containing PCSK9D377Y mutation and positively associated with elevations of plasma cholesterol concentrations. Fibrillation threshold measurement in normal dog hearts and following acute descending artery ligation. For the MSCT scanner, a clinical and a low-dose protocol for oral indications were evaluated.

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A preliminary controlled comparison of programs designed to reduce risk of eating disorders targeting perfectionism and media literacy. This paper presents a case of osteogenesis imperfecta tarda in which a large subhyaloid hemorrhage occurred. This first column on the subject addresses the clinical aspects from the standpoint of the general veterinarian. This study was carried out on MPS type I and MPS type IVA unrelated families recruited from many regions of Tunisia in order to determine the relation between consanguinity and these types of disorders. We conclude from our study that the Celsior solution is comparable to the University of Wisconsin solution for use in 12-hour heart preservation in canine models. This work presents an overview of the data obtained for SBA-15 synthesis under the reaction conditions using synchrotron based small angle X-ray scattering and small angle neutron scattering. Physical characteristics of the gravida and their association with birth weight and perinatal death. Recent development of animal models of intermittent hypoxia and techniques for exposing cell cultures to alternating cycles of hypoxia have led to new information on the effects of episodic hypoxia on oxygen-sensing mechanisms in the carotid body chemoreceptors and regulation of gene expression. It is the plasma membrane localization and its functions in the control of leaf morphology might involve in multiple biological processes such as bulliform cell development and auxin synthesis and transport. In radiology departments, these changes have focused attention on the benefits accruing from the use of computer-based information systems.

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This is in contrast to tobacco allergy for which simple avoidance is recommended. Effect of starvation on blood glucose and nonprotein nitrogen levels of the fish Clarias batrachus. Hand path priming in manual obstacle avoidance: rapid decay of dorsal stream information. Interactive workshops increase chlamydia testing in primary care--a controlled study. The synthesis of metal phosphides: reduction of oxide precursors in a hydrogen plasma. ISH related to HT results in the reduction in basal PRA probably as the result of intensified cardiac ejection function. This study focuses on investigating the evolution of nursing studies in order to know how much this transformation has contributed to the development of the nursing profession. Disclosure of potential conflicts of interest is used by biomedical journals to guarantee credibility and transparency of the scientific process. Many hospitals indicated they would like to have Coronary Care Unit training programs to which they could send nurses. Pdx1 level defines pancreatic gene expression pattern and cell lineage differentiation.

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Draft Genome Sequence of a Dyella-Like Bacterium from the Planthopper Hyalesthes obsoletus. Determination of the composition and the stability constants of complexes of mercury (II) with amino acids. Group II (mean age 56 years) had begun but had discontinued the program. Proceedings: The nature of the tryptamine receptor mediating spasmogen release from rat isolated lungs. A universal real-time PCR assay for the quantification of group-M HIV-1 proviral load. The patient underwent an empiric selective embolization of the left pudendal artery followed by a repeat angiogram of the right because of persistent tumescence. Response of rats to repeated inhalation of ethylenediamine vapors. The selection of antimicrobial agents in the hospital setting is still a largely manual task and, therefore, fraught with the potential for error periactin 4 mg side effects .

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Cytochemical study of leukocyte enzyme activity in peripheral blood of patients with endogenous infection. Plasma catecholamine levels and hemodynamic responses of severely acidotic dogs to dopamine infusion. For stage II and III tumors, radiochemotherapy should be performed in addition to surgery, preferentially as preoperative radiochemotherapy or as short-course hypofractionated radiation. There were no differences between blood collected during hip or knee surgery. Furthermore, we evaluated the effect of ASE pretreatment on infiltration of inflammatory cells into the heart, liver and lung of mice.

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E2 was suppressed in both treatment cycles of one subject and produced widely fluctuating patterns in another. The smeared aspiration specimen showed loosely cohesive, oval to round cells with moderate amounts of pale pink cytoplasm admixed with pinkish-blue, chondromyxoid material. Despite major variation in arterial disease prevalence rates between collaborating centers, risk for diabetic women appeared to equal that for diabetic men. However, these attitudes are not based on specific data at the present time. The results indicate that this method is efficient and reliable for designing sequence-specific primers. Knocking out known DSB repair components reveals that site-specific insertion is completely dependent on canonical NHEJ (DNA-PKcs, XLF and ligase-4). Axonal regeneration of peripheral adrenergic neurons: effects of antiserum to nerve growth factor in mouse. Experimental designs can also be characterized by their predictability, a measure of the ability to circumvent confounds such as habituation and anticipation.

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Separation of lipoproteins of rat serum using disc electrophoresis. Vaccinia virus E3 protein prevents the antiviral action of ISG15. The purpose of this study was to describe the MR imaging findings of ovarian mucinous cystadenomas coexisting with benign Brenner tumors. In this study, the mRNA expression of newly cloned UCP isoforms (UCP2 and UCP3) were examined in obese yellow KK and C57BL control mice. Discordant expression of human Ia-like antigens on hematopoietic progenitor cells. Here we focus on the role of FK506-binding protein 8 (FKBP8) in controlling neural cell identity through its antagonism of the Shh pathway.

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Designs were demonstrated in poly(dimethylsiloxane) (PDMS) using soft lithography and poly(methyl methacrylate) (PMMA) using micromilling and laser ablation. Pyruvated galactose and oligosaccharides from Erwinia chrysanthemi Ech6 extracellular polysaccharide. The serum values were determined of haemoglobin (Hb), total protein, uric acid, citrulline, and transaminases (SGOT and SGPT) in 47 boars and non-pregnant gilts of six breeds: eight pure Large Whites (LW), seven pure Durocs (DR), eight Landraces (LR), eight indigenous (IND), eight three-way crosses (LW X DR X Hampshire), and eight two-way crosses (LW X DR). The authors have also attempted to suggest ways in which individuals and communities can participate in the new paradigm. In our case a genetic defect for one of the key enzymes of homocysteine metabolism, may be the underlying cause. Classifying general nonlinear force laws in cell-based models via the continuum limit. An experimental study on the effects of immobilization and age on gastric ulceration. Review of the literature suggests that such a cancer of the prostate is rare, highly aggressive, and responds poorly to any mode of therapy. Chitosan-based nanocarriers have become one of the most intensively studied transmucosal nanometric drug delivery platforms.

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