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Ticlid (Ticlopidine)
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Ticlid

Ticlid is an antiplatelet drug that targets the P2Y12 receptor of platelets. Ticlid is taken orally and is a prodrug that must be metabolically activated before it can be effective. It first enters the liver and enters the endoplasmic reticulum where it is metabolized to form the active metabolite.

Other names for this medication:
Aplaket, Astic, Taispin, Ticlantin, Ticlobest, Ticlogard, Ticlogaurd, Ticlop, Ticlopid, Ticlopidine, Ticlovas, Tikla, Tikleen, Tilkon, Tyklid

Similar Products:
Neurontin, Hydrea, Suprax, Provigil, Elavil, Prometrium, Altiva, Vencare, Ralox, Gamaryl, Gravitor, Gabator, Maclar, Pironex, Endogest,

Also known as: Ticlopidine

Description

Ticlopidine is used to lessen the chance of having a stroke. It is given to people who have already had a stroke and to people with certain medical problems that may lead to a stroke. Because ticlopidine can cause serious side effects, especially during the first 3 months of treatment, it is used mostly for people who cannot take aspirin to prevent strokes.

A stroke may occur when blood flow to the brain is interrupted by a blood clot. Ticlopidine reduces the chance that a harmful blood clot will form, by preventing certain cells in the blood from clumping together. This effect of ticlopidine may also increase the chance of serious bleeding in some people.

This medicine is available only with a doctor's prescription.

Dosage

Ticlopidine should be taken with food. This increases the amount of medicine that is absorbed into the body. It may also lessen the chance of stomach upset.

Take this medicine only as directed by your doctor. Ticlopidine will not work properly if you take less of it than directed. Taking more ticlopidine than directed may increase the chance of serious side effects without increasing the helpful effects.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage form (tablets): For prevention of strokes: Adults—1 tablet (250 mg) two times a day, with food. Children—It is not likely that ticlopidine would be used to help prevent strokes in children. If a child needs this medicine, however, the dose would have to be determined by the doctor. For prevention of strokes or heart attack following heart stent procedure: Adults—1 tablet (250 mg) two times a day, with food together with your doctor's recommended dose of aspirin for up to 30 days following the procedure Children—It is not likely that ticlopidine would be used to help prevent strokes or heart attack in children. If a child needs this medicine, however, the dose would have to be determined by the doctor

Overdose

If you overdose Ticlid and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of overdosage: loss of appetite, vomiting, slow breathing, decreased activity, trouble walking.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Detailed Ticlid dosage information

Side effects

The most common side effects associated with Ticlid are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

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Arenavirus antibody in rodents indigenous to coastal southern California. Comparison of sieving matrices for on-the-fly fluorescence lifetime detection of dye-labeled DNA fragments. The core component of the COPI complex is coatomer, which is a multimeric complex that needs to be recruited from the cytosol to membrane in order to function in membrane bending and cargo sorting. A case of regenerated splenosis 20 years after splenectomy masquerading as a gastric fundic mass is reported. Data from such an experimental workflow needs to be captured, related and analyzed. The stiffness of the placenta determined by the ARFI technique is significantly higher in pre-eclampsia patients.

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Low plasma VEGF levels at 7 days after the onset of AMI were associated with a significantly increased risk for MACCE during 6 months of follow-up. Classical radical neck dissection is recommended for treating recurrent nodal disease in nasopharyngeal carcinoma. When cardiac CT is performed for quantification of coronary artery calcium (CAC) score, information on other cardiac and thoracic structures is available. There was no difference in vaspin levels between the groups according to glucose tolerance, presence of MetS, and CAD. The improvement in the oxandrolone group was associated with increased protein synthesis efficiency. The major characteristics of NCC-PPF were investigated using various analytical methods such as ultraviolet-spectrometry, circular dichroism spectrometry and TEM, which indicated that its molecular structure was still similar to that of the original apoPPF. We have studied the in vivo pathogenicity of anti-DNA monoclonal antibodies in immune deficient mice, using a panel of murine B cell hybridomas. Genetic studies on natural resistance to Moloney lymphoma (YAC) isografts.

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This study presents a strategy for combining information from different sources (literature, patent databases) and novel sequence data to identify unknown GM papaya events. The physicochemical properties of the midden soils were compared with nonmidden soils and positive soils. Homozygous C2 deficiency, lupus erythematosus, and anti-Ro (SSA) antibodies. Here we describe a femtosecond multi-color optical parametric chirped pulse amplifier (OPCPA) with simultaneous outputs from the deep-UV to the mid-IR with optical synchronization. Finally we show the results obtained by applying this method to real data collected during the calibration campaign of SuperAGILE.

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A survey-based study of wrong-level lumbar spine surgery: the scope of the problem and current practices in place to help avoid these errors. Infectious complications in patients with congenital heart defects undergoing surgery with extracorporeal circulation. Intact rat liver nuclei catalyze adriamycin irreversible interactions with DNA and nuclear proteins. On the fifth day postoperatively, fascial necrosis developed so a Bogota-bag was placed on the anterior abdominal wall and left for secondary healing. Comparison of guanethidine, methylopa, and a placebo in the hypertensive nergo woman. tarda isolates may have been previously misclassified and probably represent one or more as yet unrecognized taxa within the genus Edwardsiella. Euthyroid status is essential for normal skeletal development and the maintenance of adult bone structure and strength. Microchips also allow for parallel processing of samples by incorporating multiple channels in a single device, with a number of strategies possible for using LIF detection in these multiplex systems.

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To compensate, two enzymes, namely the ferrochelatase (HemH) and an isozyme of coproporphyrinogen III oxidase (HemF), are activated by the H2O2-responsive regulator OxyR. Hydrogen atom spectrum and the lamb shift in noncommutative QED. Permanent results after colectomy for carcinoma with restoration of continence by interposition of small intestine. Implicit acquisition of grammars with crossed and nested non-adjacent dependencies: investigating the push-down stack model. The economic perspective was that of the US health care third-party payer. Cdx1and the Pancreatitis Associated Protein I (PAP I) are concomitantly expressed in the epithelial cells of the lower part of the intestinal crypts. In analogy with low-dimensional systems, synchronization can be achieved only if the maximum Lyapunov exponent becomes negative for sufficiently large noise amplitude. THE PHENOMENON OF PARTIAL EXCLUSION OF THE BLIND SPOT IN NORMAL SUBJECTS. Scalings for slow drag and wall pressures in a plunged granular column are experimentally studied. Polyethylene glycol for button battery ingestion: a cautionary note.

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To find the most repeatable point at which to measure pulmonary arterial diameter, and to compare the repeatability of determining right ventricular output with left ventricular output. The isolated factor is distinct from the other well-described cytokines, possesses a molecular weight of 12,000-13,000, has a mildly acidic isoelectric point (at pH 6.3-6.6), is protease sensitive, and is relatively heat sensitive. Compared with controls, IBS subjects showed significantly higher levels of cortisol in the morning and lower in the evening, while they maintained the physiological circadian fluctuation (i.e. A comparative bacteriostatic evaluation of the optical isomers of threo-2-dichloroacetamido-1-(4-methylsulfinylphenyl)-1,3-propanediol. The Mainz Pouch II urinary diversion is simple and safe procedure regarding complications rate, continence and quality of life. We then derive an exact expression for the ET rate for this model system.

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Diagnosis of CUS requires surgical biopsy with immunofluorescence microscopic examination. Density functional theory calculations indicate that a progressive shift occurs of the spin density from the Ag center towards the coordinating nitrogen atoms of aza ligands, as the ligation energy increases. We demonstrate the performance of our approach through a heartbeat classification application consisting of normal and irregular heartbeats known as arrhythmia. The aim of the study was to investigate the plaque-inhibiting effects of two commercially available mouthrinses containing ASF and EO, respectively. A novel report of metallothioneins in fish bile: SDS-PAGE analysis, spectrophotometry quantification and metal speciation characterization by liquid chromatography coupled to ICP-MS. Analyses of 16S rRNA gene sequences revealed that the majority of surfactant-resistant isolates were previously undescribed species of the genus Vibrio or were of a group most closely related to Spongiobacter spp. Variable interaction of heat and procaine in potentiation of radiation lethality in mammalian cells of neoplastic origin. Allogeneic cells of the b, f, k, q, and s haplotypes failed to stimulate. Experimental validation of a kV source model and dose computation method for CBCT imaging in an anthropomorphic phantom.

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Although STA responses were also restored markedly in uremic patients, some patients still showed lower responsiveness to STA indicating the possibility of functional B cell defects. Impact of a bilingual/bicultural care team on HIV-related health outcomes. Congenital nephropathy and chronic diarrhea with hypokalemic alkalosis. Among the predicted peptides, CpMTP translocates across HeLa cells and shows successful delivery of noncovalently conjugated cargo molecules to mitochondria. The separation of free from protein-bound label by chromatography, using centrifugal elution, provides a separation method that is rapid and efficient, without the generation of large volumes of radioactive wastes characteristic of conventional chromatographic and dialysis methods. Branched-chain amino acid-enriched supplementation improves insulin resistance in patients with chronic liver disease. We evaluated the effect of raloxifene on mammographic density and MRIV in premenopausal women at increased risk for breast cancer. Transition from pemphigus erythematosus to pemphigus vulgaris: report of a fatal case partially controlled by cortisone and ACTH. Resistance has been reported in almost all species of bacteria to various classes of antimicrobial agents including recently evaluated ones.

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Enhanced survival of shrimp, Penaeus (Marsupenaeus) japonicus from white spot syndrome disease after oral administration of recombinant VP28 expressed in Brevibacillus brevis. A preliminary follow-up study of Mantoux reactors positive on initial tests and converters. The pathogenesis of this response appears to involve a disruption in cytokine balance following TNF inhibition, resulting in the up-regulation of plasmacytoid dendritic cells and the subsequent production of unopposed interferon-alpha, following a triggering event in predisposed individuals. The total proteins extracted from paclitaxel-treated HCE1 cells were analyzed by 2-dimensional gel electrophoresis (2-DE), and compared with those from untreated HCE1 cells. RECOMMENDATIONS of the International Commission on Radiological Units. The International Molecular Exchange (IMEx) consortium is an international collaboration between major public interaction data providers to share literature-curation efforts and make a nonredundant set of protein interactions available in a single search interface on a common website (http://www.imexconsortium.org/). Clinical studies have demonstrated that osteoarthritic pain is strongly linked to disability and quality of life. Compared to controls, patients showed difficulties in speed adjustment. Occasionally it is misdiagnosed, ignoring the other rare condition like KD if immunohistochemistry is not taken into consideration to differentiate.

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what type of drug is ticlopidine 2021-03-13

When transepithelial chloride transport was inhibited by furosemide intracellular chloride activity decreased and approached electrochemical equilibrium. Role of an interdisciplinary approach in the healing of long bone fractures in patients with osteogenesis imperfecta. Fabrication and modelling of fractal, biomimetic, micro and nano-topographical surfaces. The skeleton dates from approximately 810 BP (1235 calibrated AD) and is associated with Later Stone Age lithics, animal bone and shell remains from wild taxa, fruit endocarps from forest trees, phytoliths from tropical forest plants, Late Iron Age ceramics, and a single iron artifact. Clinical management decisions based on scintigraphic evidence led to less invasive drainage procedures over time and shorter hospital stay. The approval of the first biosimilar in the United States has placed increased pressure on the FDA to provide guidance on the naming convention that will be assigned to current and future biosimilars. Change and challenge in health care education and training: ASHET (American Society for Healthcare Education and Training) national membership survey results. Hearts of rats made hypertensive (BP greater than 150 mmHg) by left renal artery clipping and sham operated controls were studied in two series of experiments. A comparison of the bromsulphthalein and galactose elimination test in patients with either chronic bowel inflammation or alcoholic liver disease.

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Our method scales well and works in very large datasets where other methods fail. The effect of the supernatant of the thymic epithelial cell line, IT-45R1 (STEL), on thymocyte reactivity to mitogens. However, this relationship might be altered through the influence of personal and interpersonal determinants such as maintenance of good health and functional ability and supportive social networks. Using tridimensional finite element analysis (3D-FEA), this study evaluated the biomechanical behavior of two implant macrodesign parameters (prosthetic connection and implant body shape) in low-quality bone. Nor has cessation of risk amiloride hcl brand name factors such as smoking been assessed. Diagnosis and classification of hematologic tumors using anti-lymphocyte monoclonal antibodies. PET during complex partial seizures in 3 patients showed hypermetabolism at the site of the hypometabolic focus. A survey of systemic antibiotics prescribed in a general hospital: a step towards medical audit. Structural homology to a domain of human MLN64 associated with cholesterol transport suggests phytosteroids as putative ligands for Pru av 1. Epidural buprenorphine for postoperative analgesia after hip operations.

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In addition, we could identify three quantitative trait loci (QTLs) associated with pain-like behaviour: a sex-specific QTL on chromosome 2, one on chromosome 15 and on chromosome 6. To investigate the effects of a diaphragmatic breathing training program (DBTP) on thoracoabdominal motion and functional capacity in patients with chronic obstructive pulmonary disease. The combination effects of body acupuncture and auricular acupressure compared to sham acupuncture for body weight control: study protocol for a randomized controlled trial. The time of affiliative behaviors toward their partners was increased in RSPs, compared to that of RNSPs. In this ilosone 250 mg article, we reviewed the history of antibiotic-resistance and discussed on the future. Twenty-eight prediabetic patients underwent coronary angiography (CAG), and the Gensini score and the SYNTAX score were evaluated as the severity of CAD, while the mean amplitude of glycemic excursions (MAGE) by CGMS and 75g OGTT 120 were evaluated. The sodium-restricted patient should be cautioned against their use.

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The medial patellofemoral ligament (MPFL) is a critical structure that functions as an anatomic checkrein to help prevent lateral patellar dislocation. Simulation and design of stable channel-guided laser wakefield accelerators. Implantation with a titanium nail resulted in firm embedding of the nail and caused changes in the periosteal vasculature similar to those after reaming alone. A sample of 100 Chinese-speaking patients with stoma was recruited from a public tertiary care hospital in Singapore. This article gives an overview of the state of the art in scaling methods of generic Hill-type muscle model parameters in view of different applications and implementation of experimental data. Electron microscopic examinations showed that the mineralization appeared to be associated with collagen fibers in bone rather than with matrix vesicles in the cartilage. Nrf2-Ucp2-double knockout (DKO) mice showed characteristics of both Nrf2-KO and Ucp2-KO mice. ( E)-Methyl 2-(2-(((( Z)(1-(3,5-bis(trifluoromethyl) phenyl)-1-methoxymethylidene)amino)oxy)methyl)phenyl)-3-methoxyacrylate and ( Z)-methyl- N-( E)-2-(( E)-(5,6-dihydro-1,4,2-dioxazin-3-yl)(methoxyimino)methyl)benzyloxy-3,5-bis(trifluoromethyl)benzimidate were more effective against Erysiphe graminis and sphaerotheca fuligine than commercial strobilurin fungicides metominostrobin, azoxystrobin, and trifloxystrobin.

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Effect of restoration of AV synchrony on stroke volume, exercise capacity, and quality-of-life: can we predict the beneficial effect of a pacemaker upgrade?. Estimated continuous cardiac output (esCCO) measurement using pulse wave transit time is one noninvasive method. The most widely conserved MPS1 kinase functions involve activities at the kinetochore in both the chromosome attachment and the spindle checkpoint. Low-field interventional MRI in neurosurgery: finding ventolin medicine the right dose of contrast medium. Shwachman-Diamond syndrome in a child presenting with cystic fibrosis-type symptoms and a false-positive sweat test. Dermoscopy began in 1663, and until 1971 was used to diagnose skin lesions.

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The integration of in vivo observations with in vitro data clarifies precise signaling steps, highlights the crosstalk among pathways and identifies shared effector mechanisms in neuroinflammation. MEDLINE, EMBASE, PapersFirst, and the Cochrane Collaboration and the Cochrane Register of controlled trials were searched. Extensive in vivo classification of the latent or acute cardiotoxic manifestations associated with exposure to chemicals has been limited in the past to larger laboratory animals. This article reviews the ways in which microarray technology may be used in breast cancer research. Hypoxia/ischemia can lead to permanent brain damage and also affects other tissues of the body. Report of a case of thrice occurring retrograde intussusception of the efferent loop of jejunum through a gastroenterostomy stoma with a theory as to the aetiology. Although the satiety-promoting role of the serotonergic system in the control of food intake is well established, there is no current evidence that any selective serotonergic receptor subtype mediates the intake of a specific macronutrient. The factors associated with tooth wear were similar to those encountered in other studies.

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Triggering of a unipolar demand pacemaker by chest wall stimulation. A commercially available, computer-based ADE detection tool was effective at identifying ADEs. Utilizing a house dust mite extract (HDM)-induced murine model of asthma, we investigated whether bevacizumab, a humanized anti-VEGF monoclonal antibody, could protect the epithelial barrier in murine airways. Transcriptional coactivator with PDZ-binding motif (TAZ) is known to bind to a variety of transcription factors to control cell differentiation and organ development. Suggestive evidence for linkage was found on chromosome 18 (LOD 2.14 for frequency of use, LOD 1.97 for initiation, at 90-97 cM) and also on chromosome 19 (LOD 1.92 for early-onset at 17 cM). Upon transgenic approach, the changes in cell numbers were accompanied by marked modulation of the expression of genes implicated in the inflammatory response. The relationship of the habits of the house mouse and the terazosin capsules feeding tube mouse mite (Allodermanyssus sanguineus) to the spread of rickettsialpox. However, phenylacetyl group removal was successful on the nucleoside-level synthesis of adduct 8.

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Below 6 kHz from the carrier frequency at 3GHz, some noise, in excess with respect to the shot noise limit, is observed but remains lower than -110 dBc/Hz at 100 Hz offset frequency. Sudden unexpected death due to a clinically undiagnosed neoplasia in childhood and adolescence is uncommon. We optimized the shape of the FPM using the simulated annealing algorithm and confirmed that the optimized FPM provides a much larger focal tolerance and better final images than the CPM in the noise-free case. Minimum intensity anticoagulation therapy as primary prevention strategy. At first glance, the role can appear impersonal and distant, with little opportunity for meaningful interaction with staff. Multiple Past Concussions in High School Football Players: Are There Differences in Cognitive Functioning and Symptom Reporting?. Measurement of the gain volume in amplifying and scattering media by a two-beam spatial-correlation method. TUBERCULIN ANERGY AS A CRITERION OF BIOLOGICAL DELIMITATION OF MALIGNANT RETICULOPATHIES. Therefore, our results suggest that NO is involved in HIV-1 replication, especially that induced by TNF-alpha. Cancer of the breast: 5-year survival in a tertiary hospital in Uganda.

ticlopidine adverse drug reactions 2019-03-22

Much of the early research in this field has focused on their role in renal drug transport, yet increasing research on this family of transporters has localized them to various other epithelial tissues, including liver, brain, and placenta. Group 2: first 20 total knee arthroplasties with rotating platform. VFR was calculated in vessel segments in each patient and compared statistically to the healthy cohort by computing the z-score. Reflux of urine into the uterus, fallopian tubes, and peritoneal cavity documented by contrast studies is rare and considered abnormal. Biological and cDNA/miRNA microarray data were compared among CD44-positive/-negative HCC cells and normal hepatic cells. The disposable station will become a revolutionary technology both in clinical practice and medical education. What can family medicine practices do to facilitate knowledge management?. Implementing Delivery Room Checklists and Communication Standards in a Multi-Neonatal ICU Quality Improvement Collaborative. 174 patients with affective disorders and 258 patients with schizophrenia according to DSM-IV, as well as 229 population controls were tested.

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Anesthesiological problems of respiration and of the localization factor in neurosurgical operations. A total of 74 women treated for SUI using MONARC were compared with 32 treated using SPARC. This criterion combines separation information present in the class mean as well as the class covariance matrices. At the global level, the N terminome analysis of whole communities of proteases in tissues and organs in vivo provides a full scale understanding of the protease web and the web-sculpted proteome, so defining metadegradomics. This study provides a new GIS protocol that researchers can use to measure the distance and coverage of sidewalks along roadways. Previous work had shown that short-term priming with antigen also induced specific unresponsiveness in spleen cells on adoptive transfer. The psychological impact of a false-positive screening mammogram in Barcelona.

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Moreover, analytical chemists are aware of common errors produced in data interpretation concerning USAED. Here, we identify these challenges, provide an overview of their implications for the feasibility of bioelectrochemical wastewater treatment and explore the opportunities for future BESs. These results suggest that the expansion of these cells with FGF-2 has important consequences for facilitating their chondrogenic differentiation. A CASE OF IDIOPATHIC HYPERCATABOLIC HYPOPROTEINEMIA ASSOCIATED WITH ABNORMAL PIGMENTATION. The effects of all LCL-GC on the production of angiogenic/inflammatory factors in vivo in the B16.F10 murine melanoma model as well as on the viability and proliferation of tumor cells and endothelial cells in vitro were investigated. The optimal treatment occasion is the infant period, and laparoscopic resection may be a new safe and feasible minimally invasive surgery for this disease. BATCH-GE: Batch analysis of Next-Generation Sequencing data for genome editing assessment. Beyond the catalytic core of ALDH: a web of important residues begins to emerge.

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We reported for the first time that the non-dilated refluxing ureters showed disorganized smooth muscle fibers and altered smooth muscle cell structure, more accurately mimicking the characteristics of human cases. In contrast, another subspecies of human CSF, CSF-beta, having only GM colony-stimulating activity, only enhanced neutrophil-mediated ADCC. PVI resulted in distinct changes in magnetic strength in both the LA and the RA. Correlation between a new visual prostate symptom score (VPSS) and uroflowmetry parameters in men with lower urinary tract symptoms. Isobaric labeling and data normalization without requiring protein quantitation.

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