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Requip (Ropinirole)
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Requip

Requip works well to treat Parkinson's disease or restless legs syndrome. The IR tablet can be used for both conditions, whereas the ER tablet is only for Parkinson's disease.

Other names for this medication:
Parkirop, Ropark, Ropeway, Ropin, Ropinirole, Ropitor

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Also known as: Ropinirole

Description

Requip (ropinirole) is a dopaminergic agent and it has some of the same effects as dopamine, a naturally occuring chemical found in your body. Low levels of dopamine in the brain are associated with Parkinson's disease.

Requip is used to treat symptoms of Parkinson's disease (stiffness, tremors, muscle spasms, and poor muscle control). Ropinirole is also used to treat restless legs syndrome (RLS).

Only immediate-release Requip is approved to treat either Parkinson symptoms or RLS. Extended-release Requip XL is approved only to treat Parkinson symptoms.

Parkinson's and RLS are two separate disorders. Having one of these conditions will not cause you to have the other condition.

Dosage

Usual Adult Dose of Requip for Parkinson's Disease:

Immediate-release tablets: Initial: 0.25 mg orally three times daily After 1 week, the dose may be titrated up in weekly increments based on individual efficacy and tolerability: Week 2: give 0.5 mg orally 3 times daily Week 3: give 0.75 mg orally 3 times daily Week 4: give 1 mg orally 3 times daily After week 4, increase by 1.5 mg/day on a weekly basis up to a dose of 9 mg/day, then increase by 3 mg/day on a weekly basis up to a maximum daily dose of 24 mg Maximum Dose: 8 mg orally three times a day Extended-release tablets: Initial: 2 mg orally once daily for 1 to 2 weeks, followed by increases of 2 mg/day at 1-week or longer intervals, depending on therapeutic response and tolerability Maximum dose: 24 mg orally once a day Patients may switch from immediate-release to extended-release: The initial dose of extended-release tablet should most closely match the total daily dose of immediate-release formulation. Following conversion, adjust dose depending on response and tolerability. Comments: -If significant interruption in therapy occurs, retitration may be necessary; upon discontinuation, this drug should be gradually tapered over a 7-day period. -The extended-release tablet is designed to release medication over a 24-hour period, if rapid gastrointestinal transit occurs, and tablet residue is observed in the stool, there is a risk of incomplete release of medication, Use: For the treatment of Parkinson's disease.

Usual Adult Dose for Restless Legs Syndrome:

Immediate-release tablets: Initial: 0.25 mg orally once a day on Day 1 and Day 2 Dose titration: May titrate as follows based on individual efficacy and tolerability: Days 3 to 7: give 0.5 mg orally once a day -Week 2: give 1 mg orally once a day -Week 3: give 1.5 mg orally once a day -Week 4: give 2 mg orally once a day -Week 5: give 2.5 mg orally once a day -Week 6: give 3 mg orally once a day -Week 7: give 4 mg orally once a day Maximum Dose: 4 mg orally once a day Comments: -Take 1 to 3 hours before bedtime. -In clinical trials, this drug was not tapered prior to discontinuation. Use: For the treatment of moderate to severe Restless Legs Syndrome.

Detailed Requip dosage information

Overdose

If you overdose Generic Requip and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Generic Requip overdosage: nausea, vomiting, weakness, fainting, agitation, confusion, hallucinations, muscle twitching, tingly feeling, chest pain.

Storage

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall. Dizziness may impair your thinking or reactions. Avoid driving or operating machinery until you know how Requip XL will affect you.

Drinking alcohol can increase certain side effects of ropinirole.

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