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Protonix (Pantoprazole)

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Protonix is an inexpensive drug used to treat gastroesophageal reflux disease, inflammation of the esophagus, and Zollinger-Ellison syndrome. This drug is slightly more popular than comparable drugs. It is available in brand and generic form.

Other names for this medication:
Athzol, Cutum, Deczole, Domtal, Fulpan, Megazole, Nitzole, Pamtrazol, Pandot, Panpra, Pansaul, Pantakind, Pantoat, Panton, Pantosig, Pantotab, Pantox, Panwal, Panzel, Pdone, Pepcet, Pepticool, Prabit, Recozol, Riczole, Teemvork, Ulcipan, Zaprol

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Also known as: Pantoprazole


Pantoprazole injection is used to treat certain conditions in which there is too much acid in the stomach. It is used for short-term treatment (7 to 10 days) of gastroesophageal reflux disease (GERD) with a history of erosive esophagitis. GERD is a condition in which the acid in the stomach washes back up into the esophagus. This medicine may also be used to treat Zollinger-Ellison syndrome or other conditions (eg, cancer) in which the stomach produces too much acid.

Pantoprazole is a proton pump inhibitor (PPI). It works by decreasing the amount of acid produced by the stomach.

This medicine is given only by or under the direct supervision of your doctor.


Take Protonix exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Use the lowest dose for the shortest amount of time needed to treat your condition.

Protonix is taken by mouth (oral) or given as an infusion into a vein (injection). A healthcare provider may teach you how to properly use the injection by yourself.

Protonix tablets are taken by mouth, with or without food. The oral granules should be taken 30 minutes before a meal.

Do not crush, chew, or break a Protonix tablet. Swallow the tablet whole.

The oral granules should be sprinkled on 1 teaspoon of applesauce or apple juice and given either by mouth or through a nasogastric (NG) tube.

Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.

Use this medicine for the full prescribed length of time, even if your symptoms quickly improve.

Call your doctor if your symptoms do not improve or if they get worse while you are using this medicine.

Pantoprazole can cause false results with certain medical tests. Tell the doctor or laboratory staff that you are using this medicine.

Pantoprazole may also affect a drug-screening urine test and you may have false results. Tell the laboratory staff that you use this medicine.

Store this medicine at room temperature away from moisture, heat, and light.

Detailed Protonix dosage information


If you overdose Generic Protonix and you don't feel good you should visit your doctor or health care provider immediately.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

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The most common side effects associated with Protonix are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies have not been performed on the relationship of age to the effects of pantoprazole injection in the pediatric population. Safety and efficacy have not been established.

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A critical period model best explained the association of life course SEP with lymphocyte count, with sex-specific associations. Prenatal echographic diagnosis of ovarian cyst in a female fetus. Two of the mutations affected exon recognition probably through splice site modifications and the remaining three affected experimentally verified exon splicing enhancer (ESE) motifs. This case report describes the treatment of a 16-year-old girl with ankylosed maxillary central incisors that were noticeably infraoccluded and labially displaced. A substantial subgroup of parents demonstrate high PTSD symptom levels during the course of the year after an adolescent injury. Evaluation of gadoxetate disodium as a contrast agent for mouse liver imaging: comparison with gadobenate dimeglumine. We speculate that a subset of CBP80-bound cellular mRNAs contribute to recovery from significant cellular stress, including human retrovirus infection.

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Interviews were conducted within 30 days of injury and 2, 5, and 12 months after injury. Furthermore, the study on structure-activity relationships demonstrated that Tyr6, Gly11, and Asn14 are responsible for the anti-mycobacterial activity, and the residues at positions 15, 16 and 18 in lariatin A are critical for enhancing the activity. However, it has been difficult to predict metabolites because of the complexity of the mechanism of cytochrome P450/3A4 (CYP 3A4), which is the main metabolite enzyme of drugs. The relevance of the various methods was assessed in eight patients investigated with different diagnostic methods. In this review, we summarize a series of studies on paraspeckles that have been carried out in the decade since their discovery and discuss their physiological function and molecular mechanism. Tadpole edema virus: a viscerotropic pathogen for anuran amphibians. Thromboembolic and hemorrhagic complications in ACTH and cortisone therapy.

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We did a retrospective cohort study between 1985 and 2004 in 195 516 recipients of allografts from deceased donors. A Score for Predicting Acute Kidney Injury After Coronary Artery Bypass Graft Surgery in an Asian Population. aeruginosa) sepsis is a fetal disease with rapid progressive shock for infants and children in hospital and in the community, without initial treatment with appropriate antibiotics. Nevertheless, the Teoc protecting group of 24 after coupling to the 12-mer oligonucleotide was removed by treatment with ZnBr2 to give the adducted oligonucleotide 26. Comparison between old and young men for responses to fast velocity maximal lengthening contractions of the elbow flexors. To investigate the effect of METH1 gene transfection on fibroblast proliferation and I, III collagen synthesis in rabbit ear scar. Each remained significant in a multiple logistic regression model in which both variables were present.

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A vesicular (blistering) skin condition in a dog following putative contact exposure to Plumbago auriculata. These observations suggest that a choice stepping reaction task involves a strategy emphasizing post-response conflict and general performance monitoring of actual and required responses and also requires greater cognitive load than a choice dorsiflexion reaction. This was a randomised, open-label, parallel-group study with randomisation stratified by baseline Acute Physiology and Chronic Health Evaluation (APACHE II) scores. The link between acute physiological changes and improved outcomes associated with CLR remain to be determined. On the other hand changes in heart rate were similar in the two groups (45 and 43 beats/min respectively).4. Participants were 23 patients with mild AD and 32 healthy elderly controls (HC) and their informants who completed the Behavior Rating Inventory of Executive Function - Adult version.

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ESTIMATION OF THE MOLECULAR WEIGHT OF BETA-GLUCURONIDASE FROM PATELLA BARBARA BY GEL DIFFUSION FILTRATION. A vestibular schwannoma (VS) is a benign tumor of the VIIIth cranial nerve that can often be treated by microsurgery or radiosurgery and demonstrates high tumor control rates. The responses to injected CaCl(2) solution could be obtained repeatedly but those to successive injections of BaCl(2) solution slowly declined. Even when warm- and cold-exposed rats excrete thyroxine into their faeces at the same rate the cold-exposed animals still show a shorter half-life for blood thyroxine.6. The Occupational Safety and Health Act requires employers, including health care provides, to take all feasible measures necessary to eliminate substantial and recognized occupational hazards. THE MEDICAL ACADEMY CARRIES ON THE SIX HUNDRED YEARS OF TRADITION OF THE MEDICAL DEPARTMENT OF THE JAGIELLONIAN UNIVERSITY. The effects of acupuncture constitute a generalized systemic reaction with far-reaching consequences. Patient falls update--new approaches for reducing a perennial problem. Esophagogastroduodenoscopy and endoscopic ultrasonography revealed two gastric submucosal tumors.

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Breast conserving treatment, consisting of lumpectomy followed by whole-breast irradiation, is considered the standard of care in early-stage breast cancer. Mre11-Rad50-Nbs1-dependent processing of DNA breaks generates oligonucleotides that stimulate ATM activity. This article explores issues concerned with the litigation crisis and suggested reforms to lessen the stress caused to society. Surgical treatment of AChA aneurysms involves a significant risk of debilitating ischemic complications. The 30-day hypokinesia entailed changes in ultrastructural organization of cardiomyocytes, attesting to the tension of intracellular systems responsible for energy supply, of ionic membrane transport and the contractile apparatus. Effect of phenothiazine drugs on the stability of rat liver subcellular particles. Repetitive Noninvasive Brain Stimulation to Modulate Cognitive Functions in Schizophrenia: A Systematic Review of Primary and Secondary Outcomes. Prescribing oncologists should be aware of the potential for the development of new cases of BON in a similar fashion as with zoledronic acid. ON THE IN VITRO FORMATION OF PHOSPHOLIPIDS CONTAINING UNNATURAL BASES, VIA THE CYTIDINE MECHANISM. Using mutagenesis, EMSA, and cotransfection assays, we identified two redundant Runx binding sites in the 2DL4 promoter as essential for constitutive 2DL4 transcription, with contributions by a cyclic AMP response element (CRE) and initiator elements.

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PGE2 and 8-bromo-cyclic AMP also prompted disposal of a-BSA in cultured mesangial cells. April 11, 1975 supplement to the January 1, 1975 list of cancer programs approved by the American College of Surgeons. Propagating solitons generated by localized perturbations on the surface of deep water. Laboratory findings revealed macrocytic anemia and liver dysfunction. Akt/protein kinase B, when phosphorylated to its active form, promotes cell survival and blocks apoptosis. This case underlines the importance of tomographic imaging, even in common but persisting symptoms such as globus sensation. Human Menstrual Blood-Derived Stem Cells Ameliorate Liver Fibrosis in Mice by Targeting Hepatic Stellate Cells via Paracrine Mediators. EXPERIENCE OF THE STRASBOURG TRAUMATOLOGY CENTER IN THE TREATMENT OF PEOPLE INJURED IN HIGHWAY ACCIDENTS. The insulin pump was carried in a holster and enabled the patients to ambulate freely. Intracellular location of specific antibodies reacting with human lymphocytes.

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Multiple univariate associations with small to medium effect sizes were found between total QAE-P scores and demographic and clinical variables of the patients, institutional variables, and (non-independent) situational views of the patients. SOME FEATURES OF THE THIN STRUCTURE OF LIVER CELLS IN CHRONIC HEPATITIS AND CIRRHOSIS (ELECTRON MICROSCOPE STUDY). We present the case of a 14-year-old basketball player with footdrop secondary to compression of the common peroneal nerve from an accessory biceps femoris muscle, which was treated by neurolysis. Since the MEDPHOT phantoms are used for international comparisons and performance assessment, the performed characterization is carefully reported. In addition external environmental conditions affected hormone levels. Improvements in the care of tracheotomized patients and the application of modifications in the available variety of tubes and ancillary equipment and procedures have made this a much more effective and widely utilized way of caring for the pulmonary cripple as well as utilizing it in the classical fixed obstruction of the upper airway. Secondary metabolites as endogenous effectors of microbial cytodifferentiation. Bone marrow disorders or dysfunctions may be evaluated by blood workup, peripheral smears, marrow biopsy, plain radiographs, computed tomography (CT), MRI and nuclear medicine scan.

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The decay of spin memory in a 2D electron gas is found to be suppressed close to the metal-insulator transition. These systems are, however, relatively new, and practical experiences, especially long-term field studies, are lacking. Few studies have evaluated drug-related problems in patients undergoing elective total hip or knee arthroplasty. Alterations in dystrophin and utrophin expression parallel the reorganization of GABAergic synapses in a mouse model of temporal lobe epilepsy. The success of laser laparoscopy in the treatment of endometriosis: a two-step analysis. Here we report a sensitive mapping strategy for profiling and analysing the N-glycosylation of gp160, based on chemical release of glycans, fluorescent labelling and HPLC analysis. Acute versus chronic hypoxia in tumors: Controversial data concerning time frames and biological consequences. Optical mapping approaches to cardiac electrophysiological functions.

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Cerebral atrophy and convulsive seizures after recovery from cerebral edema and coma in a patient with fulminant hepatitis B. Building on a review of medical ethics teaching, the authors describe a method of systematically integrating value analysis into a family practice clerkship. To give a comprehensive overview of benefits and challenges from participating in group based patient education programs that are carried out by health care professionals and lay participants, aimed at promoting self-management for people living with chronic illness. Applied anatomy of the sensate latissimus dorsal muscular flap with the lateral posterior branch of the intercostal nerve. Serial changes in nailfold capillary morphology in childhood dermatomyositis. Influence of the water activity of a solid substrate on the growth rate and sporogenesis of filamentous fungi. The aim of this study was to assess retrospectively the prevalence and the predictive factors of acute pancreatitis (AP) in a population of patients referred in our endocrinology department for evaluation of very high triglyceride (TG) levels. DECALCIFICATION PROCEDURES ADAPTED TO PRESERVATION OF THE CHONDRIOME.

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In vivo studies of Escherichia coli replication forks suggest that replication forks blocked by protein-DNA complexes retain the ability to resume replication upon removal of the block for several hours. Patients with metastases that persisted after 131I therapy tended to have more advanced disease and received significantly lower radiation doses per millicurie of administered 131I than did persons whose lesions responded to treatment. These results confirm previous findings indicating continued improvement of speech recognition with time in implanted children. Whereas ex-myomiRs are progressively and specifically released by differentiating human primary myoblasts and C2C12 cultures, chemical induction of apoptosis in C2C12 cells results in indiscriminate miRNA release. Impairment of immune defenses can contribute to severe influenza infections. Altered remodeling of nucleolar machineries in cultured hepatocytes treated with thioacetamide.

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Heat treatment of hepatocellular carcinoma cells: increased levels of heat shock proteins 70 and 90 correlate with cellular necrosis. Immunity to transplantable nitrosourea-induced neurogenic tumors. Over all species, the lawful scaling of rods, cones, and retinal ganglion cell number is hypothesized to result from a conserved sequence of cell generation that defends retinal acuity and sensitivity over a large range of eye sizes. We found that c-Jun was decreased in TAK1-deficient keratinocytes and that ectopic expression of c-Jun could partially inhibit TNF-induced increase of ROS and cell death. Twelve stented coronary arteries from the 7 autopsy hearts were imaged by OCT.

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Synthesis and beta-lactamase inhibitory activities of some clavulanic acid analogues. Herpes simplex virus IE63 (ICP27) protein interacts with spliceosome-associated protein 145 and inhibits splicing prior to the first catalytic step. Acid sphingomyelinase is a water-soluble, lysosomal glycoprotein that catalyzes the degradation of membrane-bound sphingomyelin into phosphorylcholine and ceramide. The objective of this study was to investigate the effect of different animal feedings operated in two distinct PDO (protected designation of origin) cheese production areas (Parmigiano Reggiano and Grana Padano) on the microbiome of six full-scale biogas plants, by means of Illumina sequencing and qPCR techniques. The therapeutic effects of cianidanol on the rat liver cirrhosis induced by CCl4 were investigated by means of pathological examination. The KLK8 gene was analyzed by reverse transcription-PCR and direct sequencing in several human normal tissues. The pregnancy rate of infertile Turkish women was associated with emotional distress and low levels of social support were associated with increased emotional distress. Antifungal activity of some N-substituted anthranilic acid derivatives. Egg marketing in national supermarkets: products, packaging, and prices--part 3.

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Bioisosteric Replacement and Scaffold Hopping in Lead Generation and Optimization. The clinical and radiographic data of 40 knees (34 patients) with extraarticular femoral deformities that underwent consecutive CAS-TKA were compared with those of a control group that underwent conventional TKA (80 knees, 63 patients). One hundred percent of participants stated they would repeat the surgical procedure. The Provincial Palliative Care Integration Project (PPCIP) was implemented in Ontario, Canada, to enhance the quality of palliative care delivery. Paracetamol-induced 5-oxoprolinuira and high anion gap metabolic acidosis in a child on a ketogenic diet. ON A METHOD OF SEPARATION OF SERUM IODINE COMPOUNDS AFTER RADIOIODINE INGESTION. In summary, CCND1 amplification and low loxapine dosage nuclear expression of cyclin D1 predicted poor clinical outcome in postmenopausal breast cancer patients treated with either anastrozole or tamoxifen. Existing credentialing programs do not seem to regulate behavior analysis adequately.

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A total of 4530 fever cases were reported during this period including 1781 cases which were admitted in different hospitals of the town. This framework enables us to establish a clear distinction between a simple responsible discourse and genuine harm reduction practices and, among harm reduction practices, between use reduction practices and micro harm reduction practices. An objective tool is desired, which optimally prepares for Radiology boards examination. The attainment of therapeutic common side effects of lipitor 40 mg goal of cardiovascular risk factors proved to be difficult in a substantial part of patients. Thus, conditions which minimize the lactose utilization rate, such as low culture pH values or high initial lactose concentrations, favor solventogenesis at the expense of acid production.

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Compared to an operation with fixed times of batch phases, this kind of a control strategy improves the treatment quality and reduces energy consumption. Selection of the most promising candidates between the initial untargeted step and the subsequent validation phases is critical within the pipeline leading to clinical tests. ON THE INTERACTION OF VITAMIN B12 AND GASTROMUCOPROTEINS levaquin dosing in crrt IN LEUKEMIA. Overview of host defense mechanisms in systemic mycoses and the basis for immunotherapy. The role and value of an eurhythmics program in a curriculum for deaf children. By contrast, for the orexin-1 receptor, internalization of beta-arrestin 1-GFP within punctate vesicles could be observed for over 60 min in the continued presence of agonist. We developed a rapid, sensitive and specific identification method for V.

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Automatic control of guinea-pig lice with a synergised pyrethrins aerosol. The results imply that there is a threshold such that if interventions can reduce transmission so that R 0 is below 1 for long enough, then malaria will be locally eliminated. Two-dimensional NMR spectral fingerprints and relaxation data were collected on LFABP in the presence of polymeric and biomolecular crowders. Recent large association studies have revealed associations between genetic polymorphisms and myocardial infarction and coronary heart disease (CHD). Recent findings highlight the need to more fully characterize these products and their activity. A muscle biopsy revealed a vasculitic necrotizing myopathy predominantly affecting the small vessels of the lower legs. THE ANTICONVULSANT ACTIVITY OF 3-ACYLINDOLES COMPARED WITH PHENOBARBITAL. Sedation with adapted infusions of propofol and remifentanil according to the Ramsay score and a pain scale decreases the time to extubation in ICU patients requiring sedation longer than 24h but increases the rate of self-extubations. 1 A breathalyser has been used to measure blood alcohol levels at short intervals to produce an absorption curve which we have shown is reproducible.

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All 19 patients were treated with SRT: 15 with normal fractions of 1.8-2 Gy single dose up to 54-59.4 Gy. Elimination of diatrizoate by peritoneal dialysis in renal failure. Clinicians should be aware of possible biases when assessing the need of laboratory tests in patients presenting with psychiatric complaints. To date, there has been a considerable amount of interest and success in the pharmaceutical industry in the discovery of drug targets and diagnostics utilizing peptides. However, although similar in structure to plant cryptochromes, the light-response mechanism of animal cryptochromes remains entirely unknown. The existence of lymphocytes and macrophages between epithelial cells of various segments of the ductuli efferentes and the ductus epididymidis is proven, and the distribution and morphology of these cells are described. Uniting professional scientific organisations to re-evaluate anonymous heroes?. The purpose of this study was to estimate the prevalence of the Factor V Leiden mutation in patients presenting with at least one episode of venous thromboembolism and to compare it with that of the general population.

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Kinetics of ethanol tenormin brand name card production during the reactor feeding phase in constant feb-batch fermentation of molasses. Maternal sympathetic activity was upregulated during uterine contractions, and influenced the very-low-frequency components. This has led to an increase in the use of all forms of chemotherapy. Plants are thus able to optimize their growth depending on their cellular C/N status. These findings also indicated that parapoxvirus infections among wild Japanese serows seem to be caused by at least two different parapoxviruses, bovine papular stomatitis virus and orf virus. In modern networked control applications, confidentiality and integrity are important features to address in order to prevent against attacks.

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