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Nifatenol (Nifedipine)

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Nifatenol is a dihydropyridine calcium channel blocker. Nifatenol is used to: treat high blood pressure (hypertension), prevent chronic stable angina (chest pain). Nifatenol was the first calcium channel blocker to be shown to significantly reduce the development of new overt heart failure in patients with coronary artery disease. Excellent blood-pressure control in recent clinical trials has been shown to result in significant protection against stroke. Nifatenol works by opening up blood vessels in the body to lower blood pressure and improve the supply of blood and oxygen to the heart. Calcium channel blockers do not change the amount of calcium in your blood or bones.

Other names for this medication:
Adalate, Adefin, Anpect, Antrolin, Aprical, Belnif, Calchan, Calcheck, Cardicon, Cardipin, Carditas, Chronadalate, Conetrin, Cordilat, Cordipin, Corotrend, Emaberin, Lemar, Macorel, Nedipin, Nidicard, Nifangin, Nifecap, Nifecard, Nifecor, Nifed, Nifedine, Nifedipina, Nifedipinum, Nifezzard, Nifin, Nilol, Nipidin, Nipin, Noviken, Nycopin, Nyefax, Oxcord, Pabalat, Sepamit, Tredalat

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Also known as: Nifedipine


Nifedipine is used alone or together with other medicines to treat severe chest pain (angina) or high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Nifedipine is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. As a result, nifedipine relaxes blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain nifedipine. It may not be specific to Nifatenol PA 20. Please read with care.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet.

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease.

Swallow the extended release tablet whole. Do not break, crush, or chew it. It is best to take this tablet on an empty stomach.

If you are taking the extended-release tablets, part of the tablet may pass into your stool after your body has absorbed the medicine. This is normal and nothing to worry about.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For treatment of chest pain or high blood pressure: For oral dosage form (capsules): Adults—At first, 10 milligrams (mg) three times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 30 or 60 milligrams (mg) once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 90 mg once a day. Children—Use and dose must be determined by your doctor.


If you overdose Nifatenol and you don't feel good you should visit your doctor or health care provider immediately.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Nifedipine dosage information

Side effects

The most common side effects associated with Nifatenol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies have not been performed on the relationship of age to the effects of nifedipine in the pediatric population. Safety and efficacy have not been established.

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Recommendations for Premature Ovarian Insufficiency Surveillance for Female Survivors of Childhood, Adolescent, and Young Adult Cancer: A Report From the International Late Effects of Childhood Cancer Guideline Harmonization Group in Collaboration With the PanCareSurFup Consortium. Additional surgery should be encouraged after non-curative ESD to obtain long-term outcomes comparable with those of initial standard surgery. Combination chemotherapy with rituximab cures most patients, but those with recurrent disease have a poor prognosis. MKP-1 as a target for pharmacological manipulations in PC12 cell survival. The prevalence of sexually stressful events among females in the general population.

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Words Get in the Way: Linguistic Effects on Talker Discrimination. Morphological lesions of the kidneys in 59 autopsy observations of acute intestinal infections in children were studied. The importance of hysterocolpocytokaryology in the diagnosis of intraepithelial carcinoma of the uterine cervix. Arthritis is a chronic and crippling disease which affects the work effort and earnings of more than 14 million working-age victims. This synthetic route approach results in the formation of spheroidal nanoparticles (Fe3O4) with average diameter between 10 and 24nm, which were found to be superparamagnetic with saturation magnetization (Ms) ranges from 32-57emug(-1), depending on zyrtec liquid dose the concentration.

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Development of a real time PCR assay for rapid detection of Vibrio parahaemolyticus from seafood. This fixation method allowed early passive range of motion and permitted high- temovate solution cost quality MRI for followup of fracture healing and articular cartilage integrity. It is speculated that the input to supragranular layers arises from cells within layer 3c. Male Sprague Dawley fitted with indwelling jugular cannulas were used to compare the pharmacodynamic profiles of nateglinide (Nateg), glipizide (Glip) and repaglinide (Repag) through frequent blood samples following the administration of these compounds via oral gavage. Cutaneous skeletal hypophosphatemia syndrome (CSHS) is a multilineage somatic mosaic RASopathy.

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After cold shock, mt2 mRNA signals also showed time-dependent expression. A Comparative Study on the Constitutive Properties of Marketed Pesticides. The TPM1-D175N and MYBPC3-Q1061X mutations account for a substantial part of all HCM cases in the Finnish population, indicating that routine genetic screening of these mutations is warranted in Finnish patients with HCM. Other than known occupational exposures, household exposures such as home gardening should also be considered as a possible mode of exposure. Both image contrast and lateral resolution are improved in harmonic mode compared with conventional (fundamental mode) sonography. The diffusion of these less invasive treatment modalities has resulted not only in a decrease in the age-adjusted surgery rates, but also in an increase of the total number of men treated for BPH. Risk-based approaches have been increasingly accepted and operationalized in flood risk management during recent decades. The extensive morphometric data in the current study provide a framework to critically reassess the potential and limitations of animal models of atherosclerosis. PU.1(-/-) NK cells also showed defective expression of inhibitory and activating members of the Ly49 family and failed to proliferate in response to IL-2 and IL-12.

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