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Losazide (Losartan)

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Losazide belongs to a group of drugs called angiotensin II receptor antagonists (sometimes called ARB blockers). It keeps blood vessels from narrowing, which lowers blood pressure and improves blood flow. Losazide is used to treat high blood pressure (hypertension) in adults and children who are at least 6 years old. It is also used to lower the risk of stroke in certain people with heart disease.

Other names for this medication:
Cardoplus, Cormac, Enromic, Forzaar, Insaar, Lacine, Lepitrin, Lohyp, Loortan, Lopress, Losacor, Losadrac, Losamet, Losartanum, Losartic, Lozar, Lozatan, Mozartan, Osartan, Ranlozar, Rosatan, Tacardia, Temisartan, Tozaar, Zaart

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Also known as: Losartan


Losazide (losartan potassium) is an angiotensin II receptor blocker acting on the AT1 receptor subtype. Losartan potassium, a non-peptide molecule, is chemically described as 2-butyl-4-chloro-1-[p-(o-1Htetrazol- 5-ylphenyl)benzyl]imidazole-5-methanol monopotassium salt.

Losazide is a white to off-white free-flowing crystalline powder with a molecular weight of 461.01. It is freely soluble in water, soluble in alcohols, and slightly soluble in common organic solvents, such as acetonitrile and methyl ethyl ketone. Oxidation of the 5-hydroxymethyl group on the imidazole ring results in the active metabolite of losartan.

Losazide is available as tablets for oral administration containing either 25 mg, 50 mg or 100 mg of losartan potassium and the following inactive ingredients: microcrystalline cellulose, lactose hydrous, pregelatinized starch, magnesium stearate, hydroxypropyl cellulose, hypromellose, and titanium dioxide.

Losazide 25 mg, 50 mg and 100 mg tablets contain potassium in the following amounts: 2.12 mg (0.054 mEq), 4.24 mg (0.108 mEq) and 8.48 mg (0.216 mEq), respectively. Losazide 25 mg, Losazide 50 mg, and Losazide 100 mg may also contain carnauba wax.


Take Losazide tablets orally with or without food. Do not crush or chew it. Take Losazide once or twice a day at the same time. If you want to achieve most effective results do not stop taking Losazide suddenly.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children in a container that small children cannot open.

Side effects

The most common side effects associated with Losazide are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Losazide if you are allergic to Losazide components. Do not take Losazide if you're pregnant or you plan to have a baby, or you are a nursing mother. Losazide can harm your baby. Do not use Losazide if you are taking salt substitutes or potassium supplements, other blood pressure medicine, diuretic (water pill). It can be dangerous to use Losazide if you suffer from or have a history of liver disease, kidney disease, heart failure. If you want to achieve most effective results without any side effects it is better to avoid alcohol. Avoid machine driving. Do not stop taking Losazide suddenly.

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Mutation rate following treatment of Neurospora with 20-methylcholanthrene and I, 2,5,6-dibenzanthracene in tween-80. Robustness of the experimental information was checked by C and N mass balances estimation, which were satisfactory. Consistently, systemic administration to rabbits of the NOS inhibitor N(w)-nitro-L-arginine methyl ester (L-NAME) significantly reduced the angiogenicity of H.end.FB cells. Surface phases and photocatalytic activity correlation of Bi2O3/Bi2O4-x nanocomposite. By means of a simple model dipole current density the general theory is used to demonstrate numerically how superluminality enters the near-field dynamics, and how from a measurement one could be tempted to believe that superluminal propagation effects occur. Beta singulair 10mg drug class -hairpin folding by a model amyloid peptide in solution and at an interface.

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Chemical and toxicological evaluations of isolated and synthetic chloro derivatives of dibenzo-p-dioxin. The aim of this study was to analyze the prognostic factors related to the recurrence rate and overall survival of vulval melanoma patients by means of a subgroup analysis of the VULvar CANcer study. We report the case of a 40-year-old woman who presented with symptomatic gallbladder stones. To review society, ethical and anaesthesiological issues related to circumcision in children. In order to observe process parameters, the motion usually has to be disrupted. Low heritabilities for pathogen specific-mastitis resistance may be considered when including bacteriological status as a measure of mastitis presence to implement breeding strategies for improving udder health in dairy ewes.

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A screening method for 70 psychoactive drugs or drug metabolites in human serum by solid-phase extraction with subsequent high-performance liquid chromatography and electrospray ionization mass spectrometry was developed. Occurrence of neurologic deficits and wound infection was infrequent in both groups. The calculated synthesis rate of alpha 1-antitrypsin was about twice as high in the patient as in the controls. More consumer questions about costs, quality of care should be raised. Long-term changes in circulating adiponectin were differentially associated with improvement of body composition and abdominal fat distribution in men does alcohol interact with plavix and women.

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The lack of a career pathway for nurses who decide to pursue a career in nursing research and/or medical research is considered, and suggestions are made regarding the future of clinical research nursing and education. Possible use of NRP as a target for VEGF antagonists, in the context of antiangiogenic therapy, are described. Intra-stadial tick-borne Thogoto virus (Orthomyxoviridae) transmission: accelerated arbovirus transmission triggered by host death. These findings clearly demonstrate that cells of T cell lineage have the capacity to express NK activity. While the reasons for this change are unclear it is suggested that schizophrenia is characterized essentially by a state of vulnerability to the disorder. Evolution of the electronic structure of graphite and rotational-stacked multilayer epitaxial graphene as a function of the applied electric bias is investigated using first-principles density-functional theory including interlayer van der Waals interactions.

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