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Hydrea (Hydroxyurea)

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Hydrea (hydroxycarbamate, Hydrea) is a chemo drug that has helped some patients with CMML live longer. This drug comes as a capsule that's taken by mouth daily. It can bring the numbers of white blood cells and monocytes down to normal. It may also help shrink an enlarged spleen.

Other names for this medication:
Cytodrox, Droxia, Droxiget, Durea, Gindrea, Hondrea, Hydab, Hydroxyurea, Hytas, Myelostat, Neodrea, Oxyrea, Riborea, Urdox

Similar Products:
Furadantin, Thorazine, Hydrea, Omnicef, Cymbalta, Luvox, Ondet, Invoril, Lormeg, Alvergy, Zolekair, Glunas,

Also known as: Hydroxyurea


Hydrea is used to treat chronic myeloid leukemia, ovarian cancer, and certain types of skin cancer (squamous cell cancer of the head and neck).

Hydrea is also used to reduce pain episodes and the need for blood transfusions in people with sickle cell anemia. This medicine will not cure sickle cell anemia.


Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

Hydrea is usually taken once per day at the same time of day, with or without food. Swallow the pill whole with a glass of water.

Wash your hands before and after you handle Hydrea or the bottle that contains the pills. For best protection, wear disposable gloves when handling the pills.

Do not open the Hydrea capsule or crush or chew a tablet. Do not use a broken pill. The medicine from a crushed or broken pill can be dangerous if it gets in your eyes, mouth, or nose, or on your skin. If this occurs, wash your skin with soap and water or rinse your eyes with water.

If any powder from a broken pill is spilled, wipe it up at once with a damp paper towel and throw the towel away in a sealed plastic bag where children and pets cannot get to it.

Your doctor may also want you to take a folic acid supplement. Follow dosing instructions very carefully.

Hydrea can lower your blood cell counts. Your blood will need to be tested often. Your cancer treatments may be delayed based on the results.

This medicine can affect the results of certain medical tests. Tell any doctor who treats you that you are using Hydrea.

Store at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use.

Detailed Hydrea dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include drowsiness, mouth sores, and swelling with pain and purple discoloration in your hands and feet.


Store at room temperature below 30 degrees C (86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Hydrea are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use Hydrea if you are allergic to it.

Tell your doctor if you have ever had:

kidney disease (or if you are on dialysis); liver disease; a wound or ulcer on your leg; HIV or AIDS (especially if you take antiviral medicine); high levels of uric acid in your blood; or treatment with an interferon, chemotherapy, or radiation.

Using Hydrea may increase your risk of developing other types cancer or leukemia. Talk with your doctor about your specific risk.

Hydrea can harm an unborn baby. Both men and women using this medicine should use birth control to prevent pregnancy. The use of this medicine by either parent may cause birth defects.

If you are a woman, keep using birth control for at least 6 months after your last dose of Hydrea. If you are a man, keep using birth control for at least 1 year after your last dose (6 months if you took Siklos). Tell your doctor right away if a pregnancy occurs while either the mother or the father is using this medicine.

This medicine may affect fertility (ability to have children) in men. However, it is important to use birth control because Hydrea may harm the baby if a pregnancy does occur.

You should not breastfeed while you are taking Hydrea.

Older adults may be more sensitive to the effects of this medicine.

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The development and progress of ophthalmology and therapeutic services in Poland (1944-1974). Since the NHS Planning System was formally introduced in 1976 both it and the NHS itself have undergone a succession of changes and reorganisations. Persons with acquired profound hearing loss (APHL): how do they and their families adapt to the challenge?. There are limitations of the use of several classes of antihypertensive drugs in patients after kidney transplantation (KTx), as well as contradictory opinions on their effects on progression of graft dysfunction. Therapeutic use of ultrasound in certain chronic kidney diseases. Developing community-driven quality improvement initiatives to enhance chronic disease care in Indigenous communities in Canada: the FORGE AHEAD program protocol. Subjects inhaling even a small amount of aerosols from a smoke bomb should be carefully managed in a hospital setting where their respiratory function can be closely monitored. Like USP7, USP7(beta) binds specifically to an electrophilic ubiquitin probe, indicating that it contains an accessible catalytic core with potential ubiquitin-protease activity. Assessment of Administrative Medical Claims Data for Public Health Surveillance of Invasive Group A Streptococcal Necrotizing Fasciitis in Tennessee. Protein analysis of myelin isolated from the CNS of fish: developmental and species comparisons.

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USE OF A PICTURE VOCABULARY IN EVALUATING COMPREHENSION IN RESIDUAL APHASIA AFTER CVA. Such studies showed that several genes including known seed-specific factors like CRUCIFERIN1, CRUCIFERIN3 and LEA-group of genes like LEA76, LEA6, DEHYDRIN LEA and LEA-LIKE got upregulated in an ABI3-dependent manner, especially during the stress recovery phase. First experimental applications of nikozyd (isonicotinic acid hydrazide) in tuberculosis of the skin. The weight loss induced by the surgery is believed to reverse the negative impact of overweight and obesity on female reproduction, however, research is limited to in particular retrospective cohort studies and a growing number of small case-series and case-(control) studies. Such genetic insights will be useful in understanding biology and are likely to also find applications in clinical practice. Use of ATP balances for modeling oxygen-limited growth and fermentation of yeast Pichia stipitis with xylose as carbon source.

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Increase in life expectancy at birth in Japan: some implications for variable patterns of decrease in mortality. Protein W (gpW) from bacteriophage lambda is required for the stabilization of DNA within the phage head and for attachment of tails onto the head during morphogenesis. Tactile placing and associated responses of the fore and hind paws to a light tactile stimulus were studied in normal young-adult cats and kittens and their spinal littermates. We used the decomposition of the concentration index to identify factors contributing brand zyrtec vs generic zyrtec to growth inequality at 24 weeks. HIV-infected patients admitted to hospital due to influenza A H1N1 had severe morbidity. Hence, therapeutic manipulation of Lcn2 levels may provide a strategy to help manage diseases driven by alteration of the gut microbiota. The case was the first reported case accompanied by popliteal vein and artery thrombosis caused by variant lateral head of the gastrocnemius muscle. The supine radiographic findings were correlated with findings on subsequent standing erect posteroanterior and lateral radiographs. Biases in selection of messages designed to induce resistance to persuasion.

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