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Glucophage also increases your body's response to insulin, a natural substance that controls the amount of glucose in the blood. Glucophage is used alone or with other medications, including insulin, to treat type 2 diabetes. Glucophage is in a class of drugs called biguanides.

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Also known as: Metformin


MetFORMIN (Eqv-Glucophage XR) is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus.

MetFORMIN (Eqv-Glucophage XR) is sometimes used together with insulin or other medications, but MetFORMIN (Eqv-Glucophage XR) is not for treating type 1 diabetes.


Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

Take MetFORMIN (Eqv-Glucophage XR) with a meal, unless your doctor tells you otherwise. Some forms of MetFORMIN (Eqv-Glucophage XR) are taken only once daily with the evening meal. Follow your doctor's instructions.

Do not crush, chew, or break an extended-release tablet. Swallow it whole.

Measure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).

Shake the oral suspension (liquid) before you measure a dose. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).

Some tablets are made with a shell that is not absorbed or melted in the body. Part of this shell may appear in your stool. This is normal and will not make the medicine less effective.

You may have low blood sugar (hypoglycemia) and feel very hungry, dizzy, irritable, confused, anxious, or shaky. To quickly treat hypoglycemia, eat or drink a fast-acting source of sugar (fruit juice, hard candy, crackers, raisins, or non-diet soda).

Your doctor may prescribe a glucagon injection kit in case you have severe hypoglycemia. Be sure your family or close friends know how to give you this injection in an emergency.

Blood sugar levels can be affected by stress, illness, surgery, exercise, alcohol use, or skipping meals. Ask your doctor before changing your dose or medication schedule.

MetFORMIN (Eqv-Glucophage XR) is only part of a complete treatment program that may also include diet, exercise, weight control, blood sugar testing, and special medical care. Follow your doctor's instructions very closely.

Store at room temperature away from moisture, heat, and light.

Your doctor may have you take extra vitamin B12 while you are taking MetFORMIN (Eqv-Glucophage XR). Take only the amount of vitamin B12 that your doctor has prescribed.

Detailed Metformin dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose can cause severe hypoglycemia or lactic acidosis.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

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Avoid drinking alcohol. It lowers blood sugar and may increase your risk of lactic acidosis.

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Colorimetric polymer films for predicting lipid interactions and percutaneous adsorption of pharmaceutical formulations. Pulmonary root translocation for biventricular repair of double-outlet left ventricle. Relationship of blood pressure and flow during CPR to chest compression amplitude: evidence for an effective compression threshold. This study was conducted to examine the diuretic and hypouricemic effects of Orthosiphon stamineus leaf extracts. The cardiopulmonary bypass (CPB) was performed with unfractionated heparin (UFH) and the platelet glycoprotein (GP) IIb/IIIa inhibitor tirofiban. pylori testing of chronic NSAID users at increased risk for ulcer disease and eradicating the organism if present. Bidirectional long-term motor cortical plasticity and metaplasticity induced by quadripulse transcranial magnetic stimulation. The tumour responded clearly, and a radical R0 resection followed. Molecular and antigenic characterization of reassortant H3N2 viruses from turkeys with a unique constellation of pandemic H1N1 internal genes.

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Exposure to PM2.5 increased the likelihood of having severe coronary artery disease and the risk of incident myocardial infarction among patients undergoing elective cardiac evaluation. RESEARCH ON THE COMPONENTS OF THE BLOSSOMS OF WILD NERIUM OLEANDER OF LIGURIA. We also cloned the gene for zebrafish Telomerase Reverse Transcriptase (zTERT), a catalytic subunit of telomerase, and demonstrated that zLPTS protein can interact with zTERT through the TR-binding domain of zTERT. Individualising the prescription dose and number of fractions with the help of BioSuite results in improved therapeutic ratios as evaluated by radiobiological models. The effect of TSH on the acid phosphatase and thyroglobulin hydrolyzing activities in the guinea pig thyroid.

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Value and limitations of computed tomography in assessing aortocoronary bypass graft patency. Cardiovascular disease is the leading cause of death in women, as well as an important cause of disability, although many women and their physicians underestimate the risk. Congress considers legislation to encourage the development of regional trauma systems. Lung cancer with ovarian metastasis or adnexal metastasis harboring anaplastic lymphoma kinase (ALK) gene translocation is rare. To elucidate the involvement of 8-hydroxyguanine (oh(8)G) repair genes in human lung carcinogenesis, 47 lung cancer cell lines and 55 primary lung cancers were examined for somatic mutations and genetic polymorphisms in all coding exons of the MYH and APEX genes, and exon 8 of the OGG1 gene by polymerase chain reaction-single strand conformation polymorphism analysis. The proximal part of the stump is split into two longitudinal flaps and then easily pulled upward during the insertion of the sutures. Erratum to: A year for JCCS editorial changes and CCN3 KO mice at ICCNS. Quick recovery of myocardium damage in a case of subacute thyroiditis. Adenofibroma of the fimbria: a common entity that is indistinguishable from ovarian adenofibroma. Pure-tone octave masking in listeners with sensorineural hearing loss.

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Implications for the epidemiology of leishmaniases are discussed. Medicare and Medicaid regulations: conformance with Professional Standards Review regulations on review, certification, and payment activities-final regulation. Immediate arrest of haemorrhage was achieved in 17 patients (nine surgery, eight obliteration). First Cytogenetic Description of Microsternarchus bilineatus (Gymnotiformes: Hypopomidae) from Negro River (Brazilian Amazon). Special examples of sigma(X)- or ipso-complexes are formed through intermediate spiro adducts, via intramolecular SNAr. The objective of the present meta-analysis was to determine the efficacy and adverse effects of 3-weekly vs. The study was conducted in 22 newly diagnosed patients with UC and in 22 healthy controls. Today, third-generation ventilators very different from the others have forced abandonment of dogma concerning the manner in which molecules of gas enter and leave the lung. Finally, we draw some practical implications for dynamics-based protein alignment and classification and discuss possible caveats of the present approach. In order to evaluate if the extraction procedure could influence the activity we decided to perform different extractions with methanol, n-hexane and chloroform of Calamintha origanifolia, Satureja thymbra, Prangos asperula, Sideritis perfoliata, Asperula glomerata, Hyssopus officinalis, Erythraea centaurium, Marrubium radiatum and Salvia acetabulosa and test each of them.

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Solid-state dye-sensitized TiO(2) solar cells based on a sensitizer covalently wired to a hole conducting polymer. The prepared gels were evaluated for several physico-chemical parameters to justify their suitability for topical use. ASCL1 and NEUROD1 Reveal Heterogeneity in Pulmonary Neuroendocrine Tumors and Regulate Distinct Genetic Programs. Irreconcilable differences and political reality in these dark ages. Cancer surivors have limited knowledge about second primary cancer (SPC) screening and suboptimal rates of completion of screening practices for SPC. This study employed a cross-sectional survey of 193 primary care providers and psychiatrists. Ceftriaxone is a more expensive option, and may be less effective, although this requires further research. Comparison based on three-dimensional structure revealed that several motifs important both in structure and function are conserved, and the recognition of the alpha- and beta-phosphate of the ADP in the tlGK was almost identical with the recognition of the beta- and gamma-phosphate of ATP in these ATP-dependent kinases. Axons of the corpus callosum avoid both of these populations in vivo.

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Bronchoscopy in general anesthesia with evipan and pantolax (succinyl preparation). The question of whether a 4 or 9 week premating treatment period is more suitable in studies for effects on fertility and early embryonic development, and the extent to which the screening of sperm parameters may contribute to the detection of effects, has been under discussion since the ICH guideline changed in 1994/1995. We recently reported delayed colonic motility in mice fed a HFD mice for 11 weeks. Effect of Particle Size and Lattice Strain on the Debye-Waller Factors of Silicon Carbide Nanoparticles. To examine the association between decreased serum testosterone levels and artificial urinary sphincter (AUS) cuff erosion.

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Fluoridated water appears to provide a better protective effect against dental caries than fluoridated household salt among schoolchildren from developing countries. Enzymes of the carbohydrate, lipid and protein metabolism in the blood vessels of the miniature pig. Induction of a fatigue-resistant phenotype in rabbit fast muscle by small daily amounts of stimulation. After training with diagonal targets that each combine 2 unique skill components, responses to nondiagonal targets, consisting of novel combinations of the components, may emerge. Wettability Control of Gold Surfaces Modified with Benzenethiol Derivatives: Water Contact Angle and Thermal Stability. Replication study of 10 genetic polymorphisms associated with coronary heart disease in a specific high-risk population with familial hypercholesterolemia. Stathmin activity can be turned down by extensive phosphorylation on its four phosphorylatable serines, and down-regulation of stathmin activity by phosphorylation is necessary for cells to proceed through mitosis. Therefore, the responses of the intermediate and medial part of the hyperstriatum ventrale neurons to a visual imprinting stimulus were determined before, during, and after training. To explain this phenomenon, we performed binding experiments with a peptide construct of the tail to establish its specificity for Aacpn10del-25 and used cryo-electron microscopy to determine the three-dimensional (3D) structure of the GroEL-Aacpn10-ADP complex at an 8-A resolution. Recent research has highlighted the importance of the two-way interaction between the nervous and immune systems.

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