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Duphaston (Dydrogesterone)

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Duphaston is a synthetic progestogen and has a similar action to the female hormone, progesterone. It is used to treat menstrual disorders in women caused due to a lack of hormones. It is also used to reduce the risk of miscarriages or abortions. This medicine is not recommended for use in patients below 18 years of age.

Other names for this medication:
Climaston, Dabroston, Didrogesterona, Didrogesterone, Dirogest, Dufaston, Dydrogesteron, Dydrogesterone, Dydrogesteronum, Femaston, Femoston, Femphascyl, Gestatron, Isopregnenone

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Also known as: Dydrogesterone


Generic Duphaston is an orally active progestogen which acts directly on the uterus, producing a complete secretory endometrium in an estrogen-primed uterus. At therapeutic levels, Generic Duphaston has no contraceptive effect as it does not inhibit or interfere with ovulation or the corpus luteum. Furthermore, Generic Duphaston is non-androgenic, non-estrogenic, non-corticoid, non-anabolic and is not excreted as pregnanediol. Generic name of Generic Duphaston is Dydrogesterone. Duphaston is also known as Dydrogesterone. Brand name of Generic Duphaston is Duphaston.


The dosage schemes below are meant as general recommendations. For optimal therapeutic effect, the dosages are to be adapted to the nature and severity of the disorder. In irregular cycles due to endogenous progesterone deficiency Generic Duphaston 5 to 10 mg is recommended especially in irregular cycles due to shortened luteal phase (ie pre-menopause). Treatment should be repeated for several cycles. In secondary amenorrhoea Administration of Generic Duphaston in combination with an estrogen is usually recommended as in these conditions endogenous progesterone deficiency is nearly always accompanied by estrogen deficiency. 0,05 mg ethinylestradiol is administered each day from the 1st to the 25th day of the cycle, and 5 mg Generic Duphaston is added twice daily from the 11th to the 25th day. Five days after the subsequent withdrawal bleeding, the same is repeated to imitate a natural cycle. In dysfunctional uterine bleeding The symptomatic treatment is aimed at stopping the bleeding and including a subsequent withdrawal bleeding. To stop bleeding: Generic Duphaston 10 mg together with 0,10 mg ethinylestradiol twice daily for 5 to 7 days. To prevent heavy bleedings: Generic Duphaston 5 mg twice daily from day 11 to day 25 of the cycle, if necessary, combined with an estrogen during the first half of the cycle. In post-menopausal complaints If for the symptomatic treatment of post-menopausal complaints estrogens are used (hormone replacement therapy A?A?A? HRT), Generic Duphaston 10 mg is used to counteract the effects of unopposed estrogens on the endometrium. A subsequent withdrawal bleeding is induced. On continuous estrogen therapy: Generic Duphaston 10 mg twice daily during the first 12 to 14 days of each calendar month. On cyclic estrogen therapy: Generic Duphaston 10 mg twice daily during the last 12 to 14 days of the treatment. If you want to achieve most effective results do not stop taking Generic Duphaston suddenly.


If you overdose Generic Duphaston and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Generic Duphaston overdosage: diarrhea, stomach pain, hot and dry skin, confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, and muscle weakness or limp feeling.


Store at room temperature below 25 degrees C (77 degrees F) away from moisture, light and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Generic Duphaston if you are allergic to Generic Duphaston components. It is unknown how Generic Duphaston affects pregnant women or nursing mother. Do not take Generic Duphaston if you have undiagnosed vaginal bleeding or a history of thromboembolic disorders. Be careful with Generic Duphaston if you have cardiovascular, renal or hepatic impairment, diabetes mellitus, asthma, epilepsy and migraine, history of mental depression. Drug interactions can result in unwanted side effects or prevent a medicine from doing its job. Some medicines or medical conditions may interact with this medicine. Inform your doctor or pharmacist of all prescription and over-the-counter medicine that you are taking. Do not stop taking Generic Duphaston suddenly.

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Alterations in spontaneous contractions in vitro after repeated inflammation of rat distal colon. Thus, the expression of cyclin D1 in lymphoid cells does not confer a proliferative advantage but rather alters the response of cells towards apoptotic stimuli in a p53-independent manner. We advocate a modification in the design of these cords and appropriate printed warnings directed to the users of bungee cords regarding the potential for severe ocular trauma. The efficacy of opaque contact lenses as occlusion therapy for amblyopia has been established in the literature. HIV Pre-Exposure Prophylaxis (PrEP) consists of administering antiretroviral drugs to seronegative individuals with high risk practices. However, the genetic determinants of these sensing and deployment mechanisms are still poorly understood. Hypoxic hyperventilation and acute respiratory failure in the severely stressed patient: massive pulmonary arteriovenous shunts?. Her significant recovery of left arm use over a 1-year period was more extensive than what would be typically expected after the type of cerebral infarct she incurred. Cutaneous Malignancies in Pediatric Solid Organ Transplant Recipients.

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Localized scleroderma en coup de sabre (LScs) is a form of localized scleroderma thought to be an autoimmune disorder. The increased apoptosis was associated with the ratios of Bcl-2 or Bcl-xL/Bax. Effect of bovine small intestine thioredoxin on aldose reductase activity. Therefore, in severely injured blunt trauma patients, a mechanical pelvic stabilization in the pre-hospital environment, irrespective of the findings of the physical examination of the pelvis, should be considered. Socioeconomic status influences health, life expectancy, and educational success, but it has been claimed to be irrelevant to compliance and adherence issues in epilepsy.

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Topical zinc oxide was highly effective in preventing induction of ODC by UV-A irradiation at doses up to 40 J/cm2, and was significantly more effective than either PreSun or Uval. Studies on intraepithelial pavement epithelioma of the cervix uterine. Crystal structure of human thymine DNA glycosylase bound to DNA elucidates sequence-specific mismatch recognition. Therefore, impairment of the PTHrP/PTHR1 signaling pathway in humans is associated with severe abnormalities in tooth and breast development. The optimal cut-off diameter should be validated in prospective imaging studies. HSCs may play an immunoregulatory role in chronic viral hepatitis recipients to minimize the effect of immunosuppressants without affecting rejection. Here it is shown that water can be locked up in nano-pools or worm-like structures using aqueous LiCl salt solutions and can be studied with terahertz spectroscopies. A measurement of noise exposure levels of players of electronic games was made in two small arcades using a noise dosimeter. A decremental positive end-expiratory pressure (PEEP) trial after full lung recruitment allows for the adjustment of the lowest PEEP that prevents end-expiratory collapse (open-lung PEEP).

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The private delivery of Medicaid services: lessons for administrators, providers, and policymakers. Studies on different populations evaluated with different protocols have given non-uniform results and many hypothesis have been suggested as causes of low diastolic pressure: 1) excessive antihypertensive treatment, 2) decreased compliance of aorta and large arteries and 3) clinical signs of a concomitant disease. Glycogen storage disease consecutive to diabetes mellitus in an adult. However, a severe drop in turnover numbers (k(cat)) and downshifts by approximately 1-2 units of the optimal pH were observed for the oxidation of substrates, as compared with the wild type. lymphoid organs and are also seen in a substantial number of biopsy samples from advanced cutaneous T-cell lymphomas (CTCL). There was no significant difference in biofilm growth when iron was added to the low iron formula. High dose of IMI (10 mg/kg) caused that the relationship between steady-state concentration and dose of IMI cannot be expressed as a linear function.

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Current concepts of the physiopathology of asthma (practical consequences). Development of temporomandibular joint arthritis: The use of animal models. Gender-based targeting is less frequent and is usually appropriate when it occurs. The design utilizes a tensile component which screws into the femoral stem from the lateral side of the femur. Interstitial pneumonia after prolonged treatment with cyclophosphamide. We formulate the tree structure as a constrained conditional model to associate region merging with likelihoods predicted using an ensemble boundary classifier. Acquired immunodeficiency syndrome in the Netherlands and United States. Protein micropatterning thus provides a valuable tool for controlling supported membranes and for juxtaposing anchorage-dependent cells with lipid bilayers.

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Ministry of Health and some other ministries in Iran agreed to control and restrict the advertising of unhealthy products and services. Our recent studies have demonstrated a potential new mechanism of cancer suppression of immunity by impairment of antibody effector function mediated by proteolytic enzymes in the tumor microenvironment. Selective delta-opioid receptor ligands: potential PET what is a low dose of seroquel ligands based on naltrindole. Idiopathic herniation of the spinal cord is a rarely diagnosed condition. Activities and conformational fitting of 1,4-naphthoquinone derivatives and other cyclic 1,4-diones tested in vitro against Pneumocystis carinii. Conventional surgery of urethral reconstruction may lead to many complications, and its application has been greatly limited by insufficient supply of donor materials. The initial magnetic resonance imaging study at day 1 showed symmetrical diffuse lesions in the white matter and a lesion on the central portion of the corpus callosum splenium.

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EVALUATION WITH RADIOSODIUM OF THE LOCAL VASOACTIVE EFFECT OF ANGIOTENSIN AND BRADYKININ INJECTED BY THE INTRADERMAL ROUTE. For the two patients shown in Parts 1 and 2, the corresponding data are given. Although this model is well supported by data, it is not clear how activity in single neurons is altered in relation to cortical functional maps. Here we present the synthesis of four chiral overcrowded alkenes and the experimental and computational study of their photochemical and thermal behavior. A prospective investigation was performed of 200 female and male patients who were studied both preoperatively and 20, 40, 66, and 92 weeks postoperatively. The amnestic effect of the anti-chick Thy-1 antibody appears to be mediated solely by immunoglobulin G, and is species specific since anti-rat Thy-1 antibodies did not produce amnesia. Identification of new mutations in the ETHE1 gene in a cohort of 14 patients presenting with ethylmalonic encephalopathy. Each of the clones obtained were examined with flow cytometry to identify the expressions of cell-surface antigens including CD29, CD44, CD34, CD54, CD106, and ABCG2. Increased mortality in diabetes during the first 10 years of the disease.

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Expression profiles of betaTRCP1 and betaTRCP2, and mutation analysis of betaTRCP2 in gastric cancer. In addition, comparisons were made with the previous study regarding time available for clinical, educational, and research activities. Atorvastatin has previously been shown to reduce the endogenous angiogenic response to chronic ischemia in a porcine model. Because such arrays maintain their typical structure for both active and inactive centromeres, the specification of centromere activity has an epigenetic component independent of the DNA sequence. A alpha 2-beta 1-glycoprotein was isolated from horse plasma by classical methods. Cellobiose dehydrogenase (CDH) is capable of direct electron transfer (DET) on various carbon and thiol-modified gold electrodes. Upon treatment with canakinumab, many genes relevant to disease pathogenesis moved towards levels seen in the healthy volunteers. The MBom group proved to substantially suppress racemization of Cys during its incorporation mediated by phosphonium or uronium reagents.

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A dehydrated medium for the preparation of type specific extracts of group A streptococci. Medical home disparities for children by insurance type and state of residence. In Myxococcus xanthus, morphogenesis of multicellular fruiting bodies and sporulation are co-ordinated temporally and spatially. Patients with traumatic arthritis were more likely to receive WF. Attenuation of this excitotoxicity is a key point for improving the functional outcome after injury. Trb2, a mouse homolog of tribbles, is dispensable for kidney and mouse development.

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Spinal cord stimulation (SCS) applications and technologies are fast advancing. Comparison of bacterial culture, polymerase chain reaction, and a mix-enzyme-linked immunosorbent assay for the detection of Salmonella status in grow-to-finish pigs in western Canada with a Bayesian approach. Silica deposition induced by isolated aluminum ions bound on chelate resin as a model compound of the surface of microbes. Re-exposure to the self-administration context, but not to the extinction context robustly reinstated responding for the discrete nicotine cues, an pill identifier xanax yellow oval effect that was dose-dependently attenuated by Rimonabant. In contrast, these cells do not develop into melanocytes--another derivative of the neural crest--in various permissive conditions. Ethnic differences in renal handling of water and solutes in hypertension. In type 2 diabetes, hyperuricemia seems to be associated with the insulin-resistant syndrome and with early onset or increased progression to overt nephropathy, while hypouricemia is associated with worse metabolic control, hyperfiltration and a late onset or decreased progression to overt nephropathy. There was no correlation between length of stay and the route by which post-operative analgesia was administered. Organic light emitting devices, in particular, properties of polymer light-emitting transistors with printed electrodes and bilayer printed devices with in-plane emission have been investigated and discussed. The findings suggest that poor marital adjustment at the end of active treatment is a risk factor for increases in depression severity during follow-up.

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Method for the replacement of a permanently implanted arterial catheter without surgery. Additionally, expression of stemness markers (Nanog/Oct-4/CD133) contradicts the survival prognosis of OSCC patients. Effect of indinavir on the pharmacokinetics of rifampicin in HIV-infected patients. As a result, SrtA has been widely used to ligate peptides and proteins with a variety of nucleophiles, and the ligation products are useful for research in chemical biology, proteomics, biomedicine, etc. This study is the first to demonstrate the promising anti-angiogenic activity of the new andrographolide derivative AGP-40. Whole exome sequencing (WES) was performed for both sisters to identify the pathogenic mutation. The norvasc blood pressure medicine molecular specificity of a rat anti-mouse monoclonal antibody for cell surface antigens expressed by T- and B-lymphocyte subsets, erythrocytes and polymorphonuclear neutrophils (PMN) was determined. Metabolic syndrome and obesity have causative roles in the development of chronic kidney disease (CKD).

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However, the effects of these mutations on functions other than transcriptional activation are unknown. Further work is needed to assess systemic concentration with this high-dose combination in humans. Thirty-six adult patients with neurodiagnostically confirmed moyamoya disease were given presurgical neuropsychological assessments. Vascular endothelial growth factor and basic fibroblast growth factor urine levels as predictors of outcome in hormone-refractory prostate cancer patients: a cancer and leukemia group B study. Anti-idiotypic antibodies that mimic sumycin 250 mg tumour-associated antigens can stimulate anti-tumour T-cell responses. The reported experiments explored 2 mechanisms by which object descriptions are flexibly adapted to support concept learning: selective attention and dimension differentiation.

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Endoscopic microwave coagulation therapy is effective without severe complications in locally recurrent NPC patients. Initial results of treament with rifampicin of some septicemic states, 4 of which with endocarditis. Failure of vitamin E therapy in the treatment of anemia of protein-calorie malnutrition. Staged treatment with initial spanning external fixation of the ankle has proven to be a successful strategy for the treatment of these difficult fractures in many cases. BCS was diagnosed during the course of an episode of acute gastroenteritis with dehydration. By DEAE cellulose column chromatography, placental ferritin was found to contain more acidic isoferritins, while hepatic ferritin was richer in basic isoferritins. The CDT-DB not only provides a unique informatics tool for mining both spatial and temporal pattern information on gene expression in developing mouse brains, but also opens up opportunities to elucidate the transcriptome for cerebellar development. Variety-based research on the phenolic content in the aerial parts of organically and conventionally grown buckwheat.

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