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Crestor (Rosuvastatin)

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Crestor is used together with diet to lower blood levels of "bad" cholesterol (low-density lipoprotein, or LDL), to increase levels of "good" cholesterol (high-density lipoprotein, or HDL), and to lower triglycerides (a type of fat in the blood).

Other names for this medication:
Creston, Dorosur, Liparon, Provisacor, Richstatin, Rosumed, Rosuva, Rosuvas, Rosuvast, Rosuvastatin, Rosuvastatina, Rosuvastatinum, Rosuvastin, Rovartal, Rovast, Rozavel, Simestat, Sinlip, Turbovas, Visacor, Zyrova

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Also known as: Rosuvastatin


Crestor (rosuvastatin) belongs to a a group of drugs called HMG CoA reductase inhibitors, or "statins." Rosuvastatin is used together with diet to lower blood levels of "bad" cholesterol (low-density lipoprotein, or LDL), to increase levels of "good" cholesterol (high-density lipoprotein, or HDL), and to lower triglycerides (a type of fat in the blood).

Crestor is used in adults and children who are at least 8 years old to lower cholesterol and triglycerides in the blood.

Crestor is used in adults to slow the progression of atherosclerosis (a build-up of plaque in blood vessels that can block blood flow).

Crestor is used to lower the risk of stroke, heart attack, and certain other heart complications in men 50 years and older and women 60 years and older who have coronary heart disease or other risk factors.

Crestor is also used to treat hereditary forms of high cholesterol, including the heterozygous type (inherited from one parent) and the homozygous type (inherited from both parents). For the heterozygous type, Crestor can be used in children who are at least 8 years old. For the homozygous type, this medicine can be used in children as young as 7 years old.


Take Crestor tablets orally with or without food. Do not crush or chew it. Take Crestor once a day at the same time every day with water. If you want to achieve most effective results do not stop taking Crestor suddenly.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.


Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Crestor are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not take Crestor if you are allergic to rosuvastatin, or if you have:

liver disease/high levels of liver enzymes in your blood; or if you are pregnant or breastfeeding.

Do not take Crestor if you are pregnant. Rosuvastatin could harm the unborn baby or cause birth defects. Stop taking this medicine and tell your doctor right away if you become pregnant. Use effective birth control to prevent pregnancy while you are taking this medicine.

Rosuvastatin may pass into breast milk and could harm a nursing baby. Do not breastfeed while you are taking this medicine.

To make sure Crestor is safe for you, tell your doctor if you have ever had:

liver problems; kidney disease; a thyroid disorder; a habit of drinking more than 2 alcoholic beverages per day; if you are of Asian descent; or if you are 65 or older.

Crestor can cause the breakdown of muscle tissue, which can lead to kidney failure. This happens more often in women, in older adults, or people who have kidney disease or poorly controlled hypothyroidism (underactive thyroid).

People of Asian descent may absorb rosuvastatin at a higher rate than other people which may cause muscle weakness/dysfunction. Make sure your doctor knows if you are Asian. You may need a lower than normal starting dose.

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As for Europeans, the reliability of genetic testing based on these markers to determine the risk for T2D is low. The effects of radiation on prosthetic breast reconstruction before the advent of dermal allografting are reviewed. Bio-fabricated silver nanoparticles preferentially targets Gram positive depending on cell surface charge. Considerations on frequency, diagnosis, and therapy of cutaneous tuberculous infections. Bronchial asthma is one of the most common illnesses in children. Conventional forms of administration of nonabsorbable drugs and peptides often rely on parenteral injection, because the intestinal epithelium represents a major barrier to the oral absorption of these therapeutical agents into the systemic circulation. To obtain a detailed understanding of the lives of street-based commercial sex workers (SSWs) and how factors in their lives interrelate to affect their health. These findings provide new insights regarding the effects of SSRIs on inflammation, which may be crucial to devise pharmacological strategies aimed at enhancing antidepressant efficacy by means of controlling environmental conditions. BALB/c mice expressed the highest levels of the eosinophil growth and survival factor interleukin (IL)-5 in the lungs and BAL eosinophils from these animals expressed more of the anti-apoptotic proteins Bcl-xL and Bcl-2 than cells from the other strains. It can be undertaken in the cases of extremely narrow nasal fossae when an endonasal dacryocystorhinostomy is impossible.

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Both MTWA and ICA were measured simultaneously during atrial pacing in 68 patients undergoing electrophysiology study (EPS). Mediastinal cysts of fore-gut origin associated with vertebral abnormalities. The bioavailability in man of marketed brands of chlorpropamide. A COMPARATIVE CHEMICAL AND PHYSICOCHEMICAL STUDY OF SEVERAL STRAINS OF TOBACCO MOSAIC VIRUS. A retrospective review was performed of patients who had undergone placement of an arteriovenous fistula or graft. Rat Testis Damage Caused by Lead Sulfide Nanoparticles After Oral Exposure. Also in the article could be found data about the first-time created neurological center in the system of military health protection, about the center as a multifield clinical institute, its functional subdivisions: 2 psycho-neurological, 3 neurological and reanimation-intensive therapy discharges. Nanofibrillar hydrogel scaffolds from recombinant protein-based polymers with integrin- and proteoglycan-binding domains.

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Electrophysiological findings in entrapment of the median nerve at wrist and elbow. Knowledge of health effects and intentions to quit among smokers in India: findings from the Tobacco Control Policy (TCP) India pilot survey. For later components, the developmental speeding of the parietal P3b component to task-relevant stimuli also tended to be more expressed in girls than boys, whereas a late frontal negative wave N400-700 was shorter in the girls than boys from the two age groups. Since in humans, visuo-spatial information is more efficiently processed by the right hemisphere (RH) and verbal information by the left (LH), this behavioral pattern could reflect a greater age decline in RH than in LH abilities. It brings about ischemic chest pain and becomes one of the causes of myocardial infarction. The temporal history of the neornithines can be inferred from fossil taxa and the ages of vicariance events, and along with their biogeographical patterns, leads to the conclusion that neornithines arose in Gondwana prior to the Cretaceous Tertiary extinction event. Use of the Allen-Jimenez aortic cannula for the arterial perfusion in 180 cases of extracorporal circulation.

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Most of astrocytes undergo their last mitosis during this period. However, increased synaptic transmission following environmental enrichment is likely due to an increase in the number or efficacy of receptors at some synapses and the emergence of functional synaptic contacts between previously unconnected CA3 and CA1 cells. In an unselected series of 644 cases of multiple sclerosis, 25 cases with acquired pendular nystagmus were found. Targeting of serotonin 1A receptors to dopaminergic neurons within the parabrachial subdivision of the ventral tegmental area in rat brain. S100B elevation over the first 15 days after subarachnoid aneurysmal hemorrhage is associated with poor outcome after subarachnoid aneurysmal hemorrhage. The proposed method derives the dominant resonance frequency (DRF) of the vocal tract system at every sampling instant, using a heavily decaying window (HDW) for analysis. To determine the recovery of tension-relaxation and laxity in the lumbar viscoelastic structures as well as the recovery of reflexive EMG activity in the multifidus after prolonged static flexion. Proteins ejected from the phage virion probably function as an extensible tail to form a channel across the cell envelope. Strikingly, a small portion of c-mybhyper adult fish develops acute myeloid leukemia-like or acute lymphoid leukemia-like disorders with age.

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Clinical analysis of 2,576 partograms in primipara with vertex presentation. In mhATase-Tg mice, ATase activity in the liver and spleen, the metabolic rate of the de novo pathway in the liver, serum uric acid concentration, urinary excretion of purine derivatives, and T lymphocyte proliferation by phytohemagglutinin were examined. NF-kappa B activation in allografts progressed to a peak of ninefold by postoperative day and remained increased until postoperative day 6. Instruments to improve productivity and practice efficiency: the MGMA (Medical Group Management Association) cost and production surveys. Impact of health education programs on the control of urinary bilharziasis in Niger. It will also apply in Puerto Rico, Guam, and the Virgin Islands. Transient expression of four pluripotency factors (Pou5f1, Sox2, Myc, and Klf4) has been used to convert cell types but never been tested as a means to promote functional recovery from ischemic injury. Autocorrelation is a common method to estimate the duration of ultrashort laser pulses. A novel approach for the fixation of enucleated eyes during microsurgical procedures using common household plumbing accessories. Paired-pulse inhibition (PPI) and paired-pulse facilitation (PPF) were reduced.

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Comparative studies on arterial and venous blood glutathione levels in normal patients, liver disease patients and diabetics. The skin manifestations of vasculitis reflect injury by all of the classic immune reactions of Gell and Coombs. Phonetic name search technique will benefit Cleveland Clinic Foundation and its patients. Inclusive waste management is a process, and observable changes are taking place in some developing countries where waste pickers and informal waste collectors have become environmental agents. Regarding the management of ET, there is no clear indication for intervention in low-risk patients, whereas high-risk patients should be managed with chemotherapy. This study took place at the Department of Surgery, Maastricht University Medical Centre, The Netherlands. Histopathology of incidental findings in cynomolgus monkeys ( macaca fascicularis ) used in toxicity studies.

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We describe a previously healthy adolescent girl who presented with emotional lability, mental status changes, hyperreflexia, and ataxia. The refractory post-operative diaphyseal femur fracture (DFF) non-union is extremely difficult to treat and remains severe challenges for orthopedists. Retrospective cohort analysis of IMS Health LRx LifeLink database. Comparison of these profiles demonstrates that the pool of adenosine triphosphate decreases from a high level at prophase to a minimum through mitosis and increases again in the postmitotic period. Recently, many studies have documented promising results with the evaluation of circulating endothelial cells and/or progenitors, and the use of several imaging techniques, such as dynamic contrast-enhanced MRI, PET, dynamic CT scan and functional ultrasound.

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Reproducible production of protective human monoclonal antibodies by fusion of peripheral blood lymphocytes with a mouse myeloma cell line. Large urate cystolith associated with Proteus urinary tract infection. The ovulation efficiency was significantly reduced when colchicine was administered between 30 hours and 9 hours before ovulation, with maximum inhibition occurring at 20 hours before ovulation. Modifying the academic performance of the chronic psychiatric inpatient. Integrative analysis in oral squamous cell carcinoma reveals DNA copy number-associated miRNAs dysregulating target genes. With high temporal precision and reversible neuromodulation, optogenetics promises to improve existing disease models and advance our understanding of psychiatric conditions. Cervical necrotizing fasciitis in an uncontrolled type II diabetic patient. In recent years, the development of dry reagent tests has made it possible for many clinical laboratory tests to be performed not only in the laboratory but also elsewhere. Malignant adrenocortical tumors are globally hypomethylated as compared with normal and benign tumors.

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Patients with severe bilateral heterogeneous emphysema were randomized to two groups. Evaluation of pneumoperitoneum in the radiological study of liver cirrhosis. In the present review, we summarize the current and limited understanding of the cellular mechanisms underlying this cardiac anoxia tolerance. Histone H3 lysine 9 methylation, a hallmark of heterochromatin, is recognized by conserved readers called chromodomains. We compared the area of the foveal avascular zone (FAZ) and macular capillary network density at different retinal layers using swept-source optical coherence tomography angiography (OCT-A) in normal individuals and patients with diabetic retinopathy (DR). Metabolites such as creatinine and urea are established kidney function markers. Changes in sleep cycle and EEG of rats exposed to 4000 ppm toluene for four weeks. Based on these data, we suggest that the ancestral NDH- atarax 10 mg tablet dosage 1 complex could be present already at the stage of the Last Universal Cellular Ancestor (LUCA).

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Investigation on the method of isolation of tubercle bacilli from sputum applying invert soap. Accessibility to facilities was assessed using the enhanced Two-Step Floating Catchment Area method. ERK1 knockdown can block cell proliferation induced by miR-483-5p inhibition. However, there is no symmetry preventing inelastic backscattering as brought about by phonons in the presence of Rashba spin orbit coupling. The purpose of this study was to compare gastrointestinal tolerance to two enteral feeding protocols in critically ill patients. This is undertaken predominantly by a researcher engaged in a lone activity with little involvement of those contributing the stories. Use of serum amylase isoenzymes in evaluation of pancreatic function. To determine whether Ex-4 displays potential as a graft-supportive agent, we transplanted 500 murine islets under the kidney capsule of syngeneic or allogeneic streptozocin-treated recipient mice and immediately initiated daily treatment with vehicle or Ex4. This study of 20 female bartenders finds that while they are very customer oriented, they do not use their discretion to cope with problem drinkers. The authors present the history of a 79 years old female patient who had to be operated on with paraesophageal hiatal hernia causing cahexia, hematemesis, dysphagia and pain.

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The elaborate branching pattern of the Drosophila tracheal system originates from ten tracheal placodes on both sides of the embryo, each consisting of about 80 cells. Inhibitory factors derived from human tumors: isolation of factors which suppress macrophage mediated cytotoxicity. Combinations of gemcitabine (Gemzar) with cisplatin (Platinol) are among the most active new chemotherapy regimens developed for advanced non-small-cell lung cancer. Use of a photopletysmographic attachment to a ECG unit in the study of blood flow in the extremities. Evaluation of a novel in-vitro diagnostic device for the detection of urinary tract infections in diaper wearing children. THE AIM of this study was to analyze the fall frequency and some of its characteristics in hospitalized acute stroke patients. We also demonstrate that the endogenous PHGPx mRNA of untransfected H35 cells is subject to NMD. In addition, butin restored the activity and protein expression of cellular antioxidant enzymes, superoxide dismutase (SOD), and catalase (CAT) in H(2)O(2)-treated cells. Between July and September 2006, 11 patients were operated on using TAPP hernioplasty (bilateral or unilateral) and applying a Surgisis mesh albendazole oral suspension ip bandy use affixed by a fibrin sealant. The reduction of synergy by hypoxanthine varied with the MTX concentration, higher hypoxanthine concentrations being required to prevent synergy at higher MTX concentrations.

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Fracture formation in differing collagen fiber pattern of compact bone. Cutaneous adverse reactions to hydroxyurea in patients with sickle cell disease. Rib fractures in coronary bypass patients: radionuclide detection. In large metapopulations with high proximity and connectivity of neighbouring populations, different spatial management strategies yield similar outcomes. Defects in geranylgeranyl transferase I, a protein modification similar to farnesylation, do not affect resistance responses, indicating that farnesylation is zyloprim 100 mg para sirve most likely specifically required in plant defense signaling. Fluorescence quenching study indicated that their different ability to bind with pepsin. Consequently irrigation communities often have greater use of bednets, better access to improved healthcare and receive fewer infective bites compared with those outside such development schemes. Functional consequence of variation in melanoma antigen expression. Ferumoxytol is approved for the intravenous treatment of IDA in patients with chronic kidney disease. A comparison of octanol-water partitioning between organic chemicals and their metabolites in mammals.

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The importance of analysis in behavioral technology: a response to Paine and Bellamy. Trypsin treatment of viable cells from 24 spontaneous murine mammary carcinomas resulted in a dostinex dose stop breastfeeding mild but reproducible diminution in their capability to colonise the lung after i.v. A hypothesis regarding the brain modifications underlying memory. The use of multilayered capillaries for chiral separation by electrochromatography. All the chiral P,N-ligands could be liberated from the palladium template without loss of optical purity.

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In Silico and In Vitro Evaluation of Cytotoxic Activities of Farnesiferol C and Microlobin on MCF-7, HeLa and KYSE Cell Lines. Large reaction rate enhancement in formation of ultrathin AuSi eutectic layers. The petrous apex cholesteatoma around the parasellar region could be treated by intracystic removal via endoscopic, transnasal, transsphenoidal approach, without the need to strip and remove the cyst wall, and the long-term efficacy was reliable. Statin exposure was measured by cumulative statin use since 2003, weighted by the effect of the statin type and dose on the lowering of low-density lipoprotein levels. Examining the positive effects of exercise in intubated adults in ICU: a prospective repeated measures clinical study. In this article, we describe the parameters to be followed in outpatient clinic, complications not to be missed and when a hospital treatment becomes necessary. Urinary excretion of neutral 17-ketosteroids, androsterone and etiocholanolone in healthy women and women with early and advanced breast cancer. We conclude that nuclear export of 60S subunits requires the nuclear export sequence-containing nonribosomal protein Nmd3p, which directly binds to the large subunit protein Rpl10p. In addition to a high degree of variation in size, the corpus cerebellum in this group has a high degree of variation in convolution (or foliation) and symmetry, which ranges from a smooth cerebellar surface to deep, branched convexities and folds, although the functional significance of this trait is unclear.

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Pancreatic abscess in 36 dogs: a retrospective analysis of prognostic indicators. AN ANALYSIS OF THE PLAQUE ASSAY OF HERPES SIMPLEX VIRUS IN CHICK EMBRYO MONOLAYERS. Breath H2 analysis currently represents a useful clinical means of testing adults and older children for the malabsorption of CHO. This study highlights the potential of EV to contribute to the prothrombotic state, as well as to anti-cancer immunity. The phosphatase calcineurin regulates pathological TDP-43 phosphorylation. Differences between the present study and previous predictions of a lower VO2 max are explained. Dynamic analysis of olecranon osteosyntheses--an in vitro comparison of two osteosynthesis systems. In contrast, these events are increased following a symmetric lesion of the right neocortex. Hepatoxicity, characterized by biliary hyperplasia, periacinar vacuolar degeneration, hepatocytic cloudy swelling and periacinar necrosis, was observed in methylene-bis-2,6-diisopropyl-, aniline- and 2,4-dimethylaniline-treated animals.

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