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Cardizem (Diltiazem)

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Cardizem is a calcium channel blocker. It works by relaxing the muscles of your heart and blood vessels. Cardizem is used to treat hypertension, angina, and certain heart rhythm disorders.

Other names for this medication:
Altiazem, Angizem, Cardem, Cardiorex, Cartia, Coriem, Dicard, Dilacor, Dilcardia, Dilcontin, Dilcor, Dilgard, Dilter, Diltia, Diltiaz, Diltiazem, Dilticard, Diltime, Diltp, Dilzem, Heartil, Kaizem, Masdil, Onzem, Taztia, Tiamate

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Also known as: Diltiazem


Diltiazem is used alone or together with other medicines to treat angina (severe chest pain) or hypertension (high blood pressure). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Diltiazem is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. As a result, diltiazem relaxes the blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain diltiazem. It may not be specific to Cardizem CD. Please read with care.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet.

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease.

Swallow the extended-release tablet, extended-release capsule, or tablet whole. Do not open, crush, or chew it. It is best to take the extended-release capsule on an empty stomach.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For chest pain: For oral dosage form (extended-release capsules): Adults—At first, 120 milligrams (mg) once a day in the morning. Your doctor may adjust your dose if needed. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 180 milligrams (mg) once a day, either in the morning or evening. Your doctor may adjust your dose if needed. Children—Use and dose must be determined by your doctor. For oral dosage form (tablets): Adults—At first, 30 milligrams (mg) four times a day before meals and at bedtime. Your doctor may increase your dose if needed. Children—Use and dose must be determined by your doctor.

For high blood pressure: For oral dosage form (extended-release capsules): Adults—At first, 180 to 240 milligrams (mg) once a day in the morning. Your doctor may adjust your dose if needed. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 180 to 240 milligrams (mg) once a day, either in the morning or at bedtime. Your doctor may adjust your dose if needed. Children—Use and dose must be determined by your doctor.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of diltiazem can be fatal.

Overdose symptoms may include slow heartbeat, weakness, chest pain, shortness of breath, or fainting.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Cardizem LA dosage information

Side effects

The most common side effects associated with Cardizem are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use Cardizem if you are allergic to diltiazem, or if you have:

a serious heart condition such as "sick sinus syndrome" or "AV block" (unless you have a pacemaker); very low blood pressure; or if you have recently had a heart attack and you have a build-up of fluid in your lungs.

To make sure Cardizem is safe for you, tell your doctor if you have:

kidney disease; liver disease; congestive heart failure; or if you also take digoxin, or a beta blocker (such as atenolol, carvedilol, metoprolol, propranolol, sotalol, and others).

It is not known whether Cardizem will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

Diltiazem can pass into breast milk and may harm a nursing baby. You should not breastfeed while using this medicine.

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Multiple spine fractures in an adolescent snowboarder: case report. Bottle milk feeding and its association with food group consumption, growth glucophage 500mg tablets side effects and socio-demographic characteristics in Chinese young children. Monte Carlo simulation of morphologies of self-assembled amphiphilic diblock copolymers in solution. There were some subtle and long-standing neurological findings which prompted us to investigate further with a spinal magnetic resonance imaging scan. They were visualized both at angiography which showed contrast leakage to the duodenum, and at gastroscopy, where the infusion catheter could be seen in the ulcer crater. Patterns of cancer in geographic and endogamous subdivisions of the Hutterite Brethren of Canada. THE SYNTHESIS OF 6-O-CARBAMYL-L-SERINE, 6-D-SERINE, AND 6-L-THREONINE BRADYKININ. The nature and significance of hyperamylasemia follwing operation. The clinical manifestations of essential polyanglitis (periarteritis nodosa), with emphasis on the hepatic manifestations.

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Novel Intersection Type Recognition for Autonomous Vehicles Using a Multi-Layer Laser Scanner. This approach is illustrated by a model of attending to stimuli and to anticipated reinforcers in delayed matching to sample, in which the probabilities of attending are related to reinforcer rates by an expression derived from research on behavioral momentum. Predicting the coordination number within copper chaperones: Atox1 as case study. The Impact of a Concussion-U Educational Program on Knowledge of and Attitudes about Concussion. The study of extinction has been instrumental for behavioral and molecular theories of memory.

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Fine-tuning serotonin2c receptor function in the brain: molecular and functional implications. This study provides the proof of concept for using the 2.2kb hGFAP promoter to specifically manipulate PSCs for the development of targeted gene and/or drug therapy in pancreatic fibrosis, and for the screening of anti-fibrotic agents. Although balloon angioplasty can be safely, successfully, and repeatedly performed after stent restenosis, it carries a progressively high recurrence of angiographic restenosis rate during repeat 6-month follow-ups. Strategies for production of monoclonal anti-idiotype antibodies against human B cell lymphomas. Scintigraphic examination of blood flow through the vascular bed of the pulmonary artery. Several schematic maps of the cytoarchitectonic correlate of this functional entity are available, but they present partly conflicting data (number and nizoral vs t gel position of borders of the primary auditory areas) and they do not enable reliable comparisons with functional imaging data in a common spatial reference system.

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