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Biolar (Lorazepam)

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Biolar belongs to a group of drugs called benzodiazepines. Lorazepam affects chemicals in the brain that may be unbalanced in people with anxiety. Biolar is used to treat anxiety disorders. Biolar may also be used for purposes not listed in this medication guide.

Other names for this medication:
Almazine, Anxilor, Anxionil, Anxipose, Atipam, Biokalm, Biolar, Calmese, Dulozep, Larosh, Larpose, Lopam, Lopez, Loracalm, Lorakar, Loralite, Lorazam, Lorazepam, Lorazine, Loricon, Loripam, Lorivan, Lorpam, Lorvin, Lotweet, Nexlor, Norpose, Olraz, Trapex, Urpam, Zelor, Zepatrac, Zepnap

Similar Products:
Ceclor, Albenza, Rhinocort, Zithromax, Famvir, Tenormin, Abilify, Inodol, Dumotin, Ziclone, Farmalat, Skeltab,

Also known as: Lorazepam


Biolar belongs to a class of medications called benzodiazepines. These medications work by boosting the activity of gamma-aminobutyric acid (GABA) within your body.

GABA is a neurotransmitter that transmits messages between cells in different parts of your body. Increasing GABA in the body results in a tranquilizing effect that reduces feelings of stress and anxiety.

How long does it take to work?

Benzodiazepines such as Biolar are categorized based on how fast they work. Biolar is classified as having a rapid to intermediate onset (start) of action. It begins to work right away after it’s taken, but its peak effect occurs within 1 to 1.5 hours.


The Biolar dosage your doctor prescribes will depend on several factors. These include:

  • the type and severity of the condition you’re using Biolar to treat
  • your age
  • the form of Biolar you take
  • other medical conditions you may have
Typically, your doctor will start you on a low dosage and adjust it over time to reach the dosage that’s right for you. They’ll ultimately prescribe the smallest dosage that provides the desired effect.

The following information describes dosages that are commonly used or recommended. However, be sure to take the dosage your doctor prescribes for you. Your doctor will determine the best dosage to suit your needs.

Drug forms and strengths

  • Tablet: 0.5 mg, 1 mg, 2 mg
  • Solution for injection (IV): 2 mg per mL, 4 mg per mL

General dosage information

The usual oral dosage for Biolar tablets is 2 to 6 mg daily. This dosage amount is usually divided and taken two or three times daily.

Dosage for anxiety

Typical dosage: 1 to 3 mg taken two or three times daily.

Dosage for insomnia due to anxiety or stress

Typical dosage: 2 to 4 mg at bedtime.

Dosage for IV Biolar

  • Intravenous (IV) Biolar will be given by your doctor or nurse. Your doctor will determine the best dosage for your condition.

Special dosage considerations

Older adults and people with certain physical conditions may need to start with a lower dosage. This might be 1 to 2 mg, taken two or three times daily for anxiety or once at bedtime for insomnia.

What if I miss a dose?

If you miss a dose, take it as soon as you can. However, if it’s just a few hours until your next dose, skip the missed dose and take the next one on schedule.

Never try to catch up by taking two doses at a time. This can cause dangerous side effects.


In cases of a suspected Biolar overdose, it is important to establish whether the patient is a regular user of Biolar or other benzodiazepines, since regular use causes tolerance to develop. Also, one must ascertain whether other substances were also ingested.

Signs of overdose range through mental confusion, dysarthria, paradoxical reactions, drowsiness, hypotonia, ataxia, hypotension, hypnotic state, coma, cardiovascular depression, respiratory depression, and death.

Early management of alert patients includes emetics, gastric lavage, and activated charcoal. Otherwise, management is by observation, including of vital signs, support and, only if necessary, considering the hazards of doing so, giving intravenous flumazenil.

Patients are ideally nursed in a kind, nonfrustrating environment, since, when given or taken in high doses, benzodiazepines are more likely to cause paradoxical reactions. If shown sympathy, even quite crudely feigned, patients may respond solicitously, but they may respond with disproportionate aggression to frustrating cues. Opportunistic counseling has limited value here, as the patient is unlikely to recall this later, owing to drug-induced anterograde amnesia.


Store Ativan at room temperature away from moisture, heat, and light.

Keep track of the amount of medicine used from each new bottle. Biolar is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.

Side effects

The most common side effects associated with Biolar are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not use this medication if you have narrow-angle glaucoma, or if you are allergic to Biolar or to other benzodiazepines, such as alprazolam (Xanax), chlordiazepoxide (Librium), clorazepate (Tranxene), diazepam (Valium), or oxazepam (Serax).

Before taking Biolar, tell your doctor if you are allergic to any drugs, or if you have:


asthma, emphysema, bronchitis, chronic obstructive pulmonary disorder (COPD), or other breathing problems;

kidney or liver disease;

a history of depression or suicidal thoughts or behavior; or

a history of drug or alcohol addiction.

If you have any of these conditions, you may need a dose adjustment or special tests to safely take this medication.

Biolar can cause birth defects in an unborn baby. Do not use Biolar without your doctor's consent if you are pregnant. Tell your doctor if you become pregnant during treatment. Use an effective form of birth control while you are using this medication. It is not known whether Biolar passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

The sedative effects of Biolar may last longer in older adults. Accidental falls are common in elderly patients who take benzodiazepines. Use caution to avoid falling or accidental injury while you are taking Biolar. Do not give this medication to a child younger than 12 years old.

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