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Azithromycinum (Azithromycin)
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Azithromycinum

Azithromycinum is a macrolide antibiotic used for various bacterial infections such as infections of the middle ear, throat, bronchus, sinuses, skin and soft tissue. It prevents bacterial growth. Azalides are a class of macrolide antibiotics which contain a nitrogen in the macrolide ring. This imparts different pharmacokinetic properties and is associated with greater stability of the molecule. One such Azalide is the antibiotic Azithromycinum. It is also useful in treating pneumonia, typhoid, gonorrhoea, granuloma inguinale and chancroid.

Other names for this medication:
Amovin, Azalid, Azibiot, Azicip, Azigram, Azilide, Azimex, Azimit, Aziphar, Azirox, Azithral, Azithrex, Azithro, Azithromycin, Azitrin, Azitrix, Azitromicina, Azitropharma, Azomex, Azomycin, Azromax, Azyth, Clearsing, Ilozin, Kromicin, Medimacrol, Mezatrin, Neblic, Nifostin, Novatrex, Oranex, Penalox, Ribotrex, Talcilina, Thiza, Toraseptol, Tridosil, Vectocilina, Zedd, Zibramax, Zifin, Zimax, Zithromac, Zithrox, Zitrocin, Zitrolab, Zitrolid, Zitromax, Zitroneo, Zival

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Also known as: Azithromycin

Description

The drug is an antibiotic used to treat a variety of bacterial infections, such as cat-scratch disease, ear infections, infections of the skin or surrounding tissue, and throat or tonsil infections.

Azithromycinum is also used to treat lung and other respiratory infections, such as bronchitis, sinusitis, community acquired pneumonia, some cases of chronic obstructive pulmonary disease (COPD), and whooping cough (pertussis).

Doctors may also prescribe azithromycin for genital infections and sexually transmitted diseases, such as gonorrhea, infections of the urethra or cervix, genital ulcers, and severe pelvic inflammatory disease.

Azithromycinum belongs to group of drugs known as macrolide antibiotics. They work by preventing bacteria from making their own proteins.

As with other antibiotics, to prevent the spread of drug-resistant infections, the Food and Drug Administration (FDA) strongly advises doctors to prescribe the drug only when there is proof, or a strong suspicion, that the infection is caused by bacteria against which Azithromycinum is effective.

The FDA first approved Azithromycinum under the brand name Zithromax in 1991. Pfizer Pharmaceuticals manufactures the drug.

Dosage

This section provides information on the proper use of a number of products that contain azithromycin. It may not be specific to Azithromycinum Tri-Pak. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

This medicine comes with a patient information leaflet. Read and follow the instructions carefully. Ask your doctor if you have any questions.

You may take Azithromycinum® oral liquid or tablets with or without food.

Shake well the bottle of Azithromycinum® oral liquid before each use. Measure your dose correctly with a marked measuring spoon, oral syringe, or medicine cup. The average household teaspoon may not hold the right amount of liquid.

Measure the Zmax® extended-release oral suspension with a marked measuring spoon, syringe, or cup. You or your child must take this medicine within 12 hours after it has been mixed with water. It is best to take the Zmax® extended-release oral suspension on an empty stomach or at least 1 hour before or 2 hours after a meal. If your child does not use all of the medicine in the bottle, throw it away after you give the dose.

If you or your child vomits within one hour of taking the Zmax® extended-release oral suspension, call your doctor right away to see if more medicine is needed.

Keep using this medicine for the full treatment time, even if you or your child feel better after the first few doses. Your infection may not clear up if you stop using the medicine too soon.

If you are taking aluminum or magnesium-containing antacids, do not take them at the same time that you take Azithromycinum®. These medicines may keep azithromycin from working properly. However, you can take antacids with Zmax®.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage form (extended-release suspension): For treatment of pneumonia: Adults—2 grams (g) once as a single dose. Children weighing 34 kilograms (kg) or more—Dose is based on body weight and must be determined by your doctor. The dose is usually 2 grams once a day, taken as a single dose. Children 6 months of age and older weighing less than 34 kg—Dose is based on body weight and must be determined by your doctor. The dose is usually 60 milligrams (mg) per kilogram (kg) of body weight once a day, taken as a single dose. For treatment of sinusitis: Adults—2 grams (g) once a day as a single dose. Children—Use and dose must be determined by your doctor. For oral dosage forms (suspension or tablets): For treatment of infections: Adults—500 to 2000 milligrams (mg) once a day, taken as a single dose. Depending on the type of infection, this may be followed with doses of 250 to 500 mg once a day for several days. Children 6 months of age and older—Dose is based on body weight and must be determined by your doctor. The dose is usually 10 to 30 milligrams (mg) per kilogram (kg) of body weight once a day, taken as a single dose. Depending on the type of infection, this may be followed with doses of 5 to 10 mg per kg of body weight once a day for several days. Children younger than 6 months of age—Use and dose must be determined by your doctor. For treatment of pharyngitis or tonsillitis: Adults—500 milligrams (mg) on Day 1 (the first day), taken as a single dose. Then, 250 mg on Day 2 through Day 5. Children 2 years of age and older—Dose is based on body weight and must be determined by your doctor. The dose is usually 12 milligrams (mg) per kilogram (kg) of body weight once a day for 5 days. Children younger than 2 years of age—Use and dose must be determined by your doctor.

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Storage

Store at room temperature between 59-77 F (15-25 C) away from light and moisture, kids and pets. Do not store the liquid longer than 10 days.

Side effects

The most common side effects associated with Azithromycinum are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take antacids that contain aluminum or magnesium within 2 hours before or after you take azithromycin. This includes Acid Gone, Aldroxicon, Alternagel, Di-Gel, Gaviscon, Gelusil, Genaton, Maalox, Maldroxal, Milk of Magnesia, Mintox, Mylagen, Mylanta, Pepcid Complete, Rolaids, Rulox, and others. These antacids can make azithromycin less effective when taken at the same time.

Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, stop taking azithromycin and call your doctor. Do not use anti-diarrhea medicine unless your doctor tells you to.

Avoid exposure to sunlight or tanning beds. Azithromycinum can make you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.

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DISCUSSION/IMPLICATIONS FOR NURSING: This analysis of a series of stand-alone cross-cultural studies provides lessons about how conceptual issues, such as the uniqueness of perceived quality of life and the experience of new motherhood, can be addressed. These measurements are the first application of solid-state NMR methods in a structural study of a peptide-protein complex. The participants were 96 Chinese seventh-grade students (41 male, 51 female and 4 unreported) from a secondary school in Hong Kong. The concept of fetal gene therapy is an extension of this principle in that diseases in which irreversible changes occur at or beforebirth can be prevented by gene supplementation or repair in the fetus or associated maternal tissues. Using standardized scales, children reported on bullying victimization, psychological problems, and potential risk and protective factors at individual, peer, family, and community levels.

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Seventy-one consecutive couples who suffered from unexplained infertility and underwent controlled ovarian hyperstimulation (COH) and IUI were enrolled into the study. In this chapter, we present the method of isotopically nonstationary (13)C MFA (INST-MFA), which is applicable to autotrophic systems that are at metabolic steady state but are sampled during the transient period prior to achieving isotopic steady state following the introduction of (13)CO2. The level of concordance between allergic symptoms induced on exposure to pollen in a pollen challenge chamber (PCC) versus the natural season is unknown. Spine surgery referrals redirected through a multidisciplinary care pathway: effects of nonsurgeon triage including MRI utilization. An imbalance between proliferation and apoptosis is one of the main features of carcinogenesis. Anterior/posterior (A/P) spreads were measured on master casts associated with the interim prostheses. Misdiagnosis of Munchausen syndrome by proxy: a literature review and four new cases.

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However, injured neurons could induce injury in other neurons regardless of TLR-4 competency. Benefits of 3D rotational DSA compared with 2D DSA in the evaluation of intracranial aneurysm. Construction and expression of eukaryotic expression vector for pEGFP-GPC3. Here, two pathways to achieve such purpose are highlighted, either by non-equilibrium growth of MoS2 dendrites or throughout high-density nucleation of MoS2 nanoflakes directly on the electrode materials. Interaction effects between sender and receiver processes in indirect transmission of Campylobacter jejuni between broilers.

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The mean power frequency and the duration of the EMG during the electromechanical delay did not change, while the root-mean-square amplitude increased. We used a computerized PRO monitoring to determine HRQOL reference values for outpatient kidney transplant patients. Summary findings of a systematic review of the ultrasound assessment of synovitis. Lesion size was assessed at 6 h, and 1, 3, and 7 days using MR imaging and histology. Among herbal medicines, the golden plaster is the preferred and most commonlyused method in China to reduce pain in patients with knee osteoarthritis, as it causes few adverse effects.

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Bariatric surgery is becoming more and more influential as efficient weight loss therapy for the morbidly obese. There are significant differences in modelled AFstY between species, which are predominantly determined by differences in the timing and length of the growing season, the periods during which soil moisture deficit limits stomatal conductance, and adaptation to soil moisture stress. The Expanding Complexity of Estrogen Receptor Signaling in the Cardiovascular System. This study investigates the impact of injury severity, patient origin, and payer on charges and payments associated with treatment of femoral fractures at a Level I trauma center. To study the effect of tetrahydropalmatine (THP) analogs on Fos protein expression induced by formalin-pain and elucidate analgesic mechanism of THP analogs. Abuse of medicines for performance enhancement in sport: why is this a problem for the pharmaceutical industry?. Herein, we present a novel web server, CPSS (a computational platform for the analysis of small RNA deep sequencing data), designed to completely annotate and functionally analyse microRNAs (miRNAs) from NGS data on one platform with a single data submission. Prolonged exposure of hematopoietic cells to RA did not affect the functional activity of neutrophils and macrophages, i.e.

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Interdental acrylic stabilisation of canine tooth root and mandibular fractures in a dog. One hundred and forty-three patients presenting with ankle sprains within 24 h of injury were entered into a double blind study. Increased NO concentration and abnormal IL-17 and IL-18 expression were induced by genital infection and induced damage to male reproductive capacity, thereby causing male infertility. This article presents the current knowledge about bone replacements and reviews the available sources, techniques, and indications of the various types of autograft, allograft, and synthetic agents that are used in contemporary hip and knee replacement surgery. Although changes in hereditary, allergic and environmental factors must be considered as possible causes of this increase, its suddenness points to risk factors that change rapidly.

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Establishment of data warehouse of needling and moxibustion literature based on data mining. In contrast to their effect on EPO synthesis, neither IL-1beta nor TNF-alpha decreased VEGF production. Propranolol treatment led to an externalization of beta-receptors from light vesicle to sarcolemmal fractions. PGF2 alpha was determined directly as the n-butylboronate derivative. Further validity and factorial studies are necessary in larger and more heterogeneous samples.

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Areas of unsuppressed water and lipid resonances were used to calculate the lipid-to-water ratio (LWR). Only limited data are available on AT after TBI and practical decision making is based on the opinion of experts. Stable AH in young men is associated with signs of remodeling of CCA walls and increase of their rigidity. Fifteen patients had bilateral cataract, and 6 had unilateral cataract. Biomarkers characterization of circulating tumour cells in breast cancer patients.

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One fourth of the adult population in Europe suffer from respiratory allergy. The walls of the apical portion of the canal were covered by a bacterial biofilm, which was continuous with a thick extraradicular biofilm covering the cementum and dentin in resorptive defects. There was history of untreated traumatic laceration of the right upper lid. Data on depression were extracted from the Vrije Universiteit naturalistic cohort on routine care monitoring with the Minimum Data Set of the Resident Assessment Instrument. Research evidence is beginning to emerge that social problem-solving can improve the social functioning of people with personality disorder. To determine whether a decreased corneal thickness is a primary factor in the lower intraocular pressure readings found in normal-tension glaucoma patients. Is nonalcoholic fatty liver disease in children the same disease as in adults?. This case report of 3 patients shows the variety of possible injuries combined with SD. Crystal structures showed that RF1 and RF2 are in an open conformation when bound to the ribosome but are in a closed conformation when not bound to the ribosome. Results of CT and MRI explorations in 8 patients with cerebrospinal fluid (CSF) fistulae are reported and compared with surgical findings in 7.

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Antibodies to the central conserved region of respiratory syncytial virus (RSV) G protein block RSV G protein CX3C-CX3CR1 binding and cross-neutralize RSV A and B strains. These results led to the idea that the mcm2AA strain is unable to respond properly to DNA damage. Then, the characteristics of the printed scaffolds were assessed by measuring molecular weight (M w), glass transition temperature (T g), in vitro degradation, compressive modulus, and cytocompatibility. We performed this study to determine the prevalence of hepatitis D in the general population of Qom province and the potential risk factors for acquiring HDV. The results indicated that the proposed constrained nonlinear KF achieved the best performance among the evaluated state estimators and that the state estimator combined with the I/O configuration that has ICP as the measured output can potentially be used to estimate CBFV continuously. The role of Epstein-Barr viruses in the etiopathogenesis of rheumatoid arthritis. Heat stress and flame protective clothing in mine rescue brigadesmen: inter- and intraindividual variation of strain. Although most laboratories used culture-based methods, procedures differed widely and most did not adhere to existing guidelines, likely resulting in underdiagnosis.

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Therapeutic transplantation of a skin graft from the partner into an infertile female patient. Group sequential trials revisited: simple implementation using SAS. We have investigated the specificity of TB notification for the diagnosis of this disease. Gradual postischemic reoxygenation as protection against spinal cord ischemia in an experiment. Comparative mapping of 18 equine type I genes assigned by somatic cell hybrid analysis. AF-triggered inadequate shock therapy - should be the object of continuous monitoring. Novel endoscopic management of a late complication following TVT insertion for stress urinary incontinence. Effects of smoking marijuana on focal attention and brain blood flow. The rods have been produced with diameters ranging from 200 nm to 1 mum and aspect ratios as high as 125.

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Viral antigen in a single mosquito infected with MVE could be detected in a pool of 500. Deconvolution of the FTIR spectrum of WGA alone indicated the presence of few alpha-helices and beta-sheets, in contrast to many other lectins. Seven geriatric syndromes (multiple comorbidities, cognitive impairment, frailty, disability, malnutrition, impaired homeostasis, and chronic inflammation) were associated with poor survival. In particular, Notch plays an important role in the commitment between the mesodermal and neuroectodermal lineages and seems to regulate cardiogenesis in mesodermal precursors. Vascular smooth tenormin medicine muscle cell (VSMC) membrane potential was recorded with microelectrodes. Whisker plucking before DRN stimulation could enhance the responsiveness of barrel cortex neurons to PW deflection and decrease the responsiveness to AW deflection. Irrespective of the type of circadian rhythm (entrained or free-running), there was a significant correlation between the characteristics of the 6-sulphatoxymelatonin and cortisol rhythms in the blind subjects.

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Attitudes of Hungarian dental professionals to tobacco use and cessation. Under these circumstances, a system that can cleocin t gel how supplied automatically determine in advance which article has a higher priority for curation can effectively reduce the workload of biocurators. The increase of HCV replication by BAs may influence the efficacy of antiviral treatment in vivo and may improve replication of primary HCV genomes in cell culture. To get more insight into the transcriptional events triggered by cytokinin in roots and shoots, we studied genome-wide gene expression in cytokinin-treated and cytokinin-deficient roots and shoots. Peritoneal lavage with mercuric chloride: toxic and unnecessary. We report on the spontaneous formation of hierarchical wrinkling patterns in Cr films deposited on silicone oil drops with constrained edges.

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To understand cultural differences in the impact of cancer (IOC) by (i) performing an independent psychometric evaluation of the Dutch version of the Impact of Cancer Scale version 2 (IOCv2) in a non-Hodgkin lymphoma (NHL) sample and (ii) examining differences between Dutch and American NHL survivors in perceived IOC and identifying associations with socio-demographic and clinical characteristics. H-PRT significantly improved 6MW ability in older adults with intermittent claudication from PAD, whereas L-RT and unsupervised walking did not. Water-extractable magnesium, manganese and copper in leaves and herbs of medicinal plants. ultram 100 mg tablets The original observations were confirmed, with an overall odds ratio of 1.4 across samples. The cohort was divided into two groups according to whether or not neo-adjuvant treatment had been given. Arachidonate lipoxygenase products may play significant roles in the regulation of fetal and uteroplacental hemodynamics and it is speculated that the formation of leukotriene B4 predominantly by tissues of fetal origin may be of significance in the immunologic adaptations of pregnancy. The CECs were analyzed to determine if they provided reliable formative information, identified marginal performances, and identified differences between raters, settings, rotations, and aspects of clinical performance evaluated. Data from patient diaries, follow-up visit forms, and medical contact forms for the 299 patients enrolled in the MSH were analyzed.

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The amplitudes of the long latency SSEP components increased significantly with remifentanil, decreased with propofol, and did not change with placebo. To evaluate whether results of alcohol screening with the Alcohol Use Disorders Identification Test - Consumption (AUDIT-C) questionnaire-up to a year before surgery-were associated with the risk of postoperative complications. This technique combines the advantages of local antibiotic delivery with the mechanical stability afforded by an intramedullary nail. The distribution of xanax 1 mg pill identification sequence variation is determined by a dynamic balance of conservative and innovative evolutionary forces. Platelet scintigraphy is useful for diagnosing transient ischemic attacks as being secondary to an aneurysm and was proved to provide direct evidence of a thromboembolic source in vivo. Sera from different CREST patients vary in their ability to bind to chromosome arms in addition to the centromeric region.

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