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Avidal (Metronidazole)
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Avidal

Flagyl is an oral antiprotozoal and antibacterial. It is thought to work by entering the bacterial cell, acting on some components of the cell, and destroying the bacteria. Treating certain infections caused by bacteria or amoebas. It may also be used for other conditions as determined by your doctor.

Other names for this medication:
Aldezol, Amebidal, Anaeromet, Avidal, Bemetrazole, Birodogyl, Buccoval, Camezol, Collazole, Colpofilin, Corsagyl, Cresac, Diazole, Dumozol, Efloran, Flagystatine, Geloderm, Ginerella, Grinazole, Klont, Metrocev, Metrocream, Metrocreme, Metronidazols, Metrozole, Missilor, Molazol, Monizole, Mtrocol, Nidagel, Nidazol, Nidazole, Nidazyl, Nizole, Promuba, Protogyl, Rhodogil, Rosaced, Servizol, Stomorgyl, Supplin, Tolbin, Torgyl, Trichex, Trichopol, Trichozole, Vagilen

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Also known as: Metronidazole

Description

Metronidazole injection is used to treat serious bacterial infections in different areas of the body. It is also used to prevent infections in the bowels before and after surgery for some patients.

Metronidazole belongs to the class of medicines known as antibiotics. It works by killing bacteria or preventing their growth. However, this medicine will not work for colds, flu, or other virus infections.

This medicine is to be given only by or under the direct supervision of your doctor.

Dosage

In the Female. One-day treatment – two grams of Avidal, given either as a single dose or in two divided doses of one gram each, given in the same day. Seven-day course of treatment – 250 mg three times daily for seven consecutive days. There is some indication from controlled comparative studies that cure rates as determined by vaginal smears and signs and symptoms, may be higher after a seven-day course of treatment than after a one-day treatment regimen.

The dosage regimen should be individualized. Single-dose treatment can assure compliance, especially if administered under supervision, in those patients who cannot be relied on to continue the seven-day regimen. A seven-day course of treatment may minimize reinfection by protecting the patient long enough for the sexual contacts to obtain appropriate treatment. Further, some patients may tolerate one treatment regimen better than the other.

Pregnant patients should not be treated during the first trimester In pregnant patients for whom alternative treatment has been inadequate, the one-day course of therapy should not be used, as it results in higher serum levels which can reach the fetal circulation.

When repeat courses of the drug are required, it is recommended that an interval of four to six weeks elapse between courses and that the presence of the trichomonad be reconfirmed by appropriate laboratory measures. Total and differential leukocyte counts should be made before and after re-treatment.

Overdose

Single oral doses of Avidal, up to 15 g, have been reported in suicide attempts and accidental overdoses. Symptoms reported include nausea, vomiting, and ataxia. Oral Avidal has been studied as a radiation sensitizer in the treatment of malignant tumors. Neurotoxic effects, including seizures and peripheral neuropathy, have been reported after 5 to 7 days of doses of 6 to 10.4 g every other day.

There is no specific antidote for Avidal overdose; therefore, management of the patient should consist of symptomatic and supportive therapy.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Avidal dosage information

Side effects

The most common side effects associated with Avidal are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

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The description of acute anterior uveitis in spondyloarthritis and in juvenile idiopathic arthritis is omitted in this article but will be dealt with elsewhere in this issue. In the present study potential allergens have been characterised using sera from A. Delayed tooth eruption associated with an ameloblastic fibro-odontoma. Inhibition of the ERK1/2 by PD98059 could downregulate Bcl-2 and upregulate Bax and was associated with restoration of sensitivity to gemcitabine in BXPC-3 cells. Consistently, we found an early gene expression signature linked to IP-10. Performance Evaluation of the Serum Thyroglobulin Assays With Immunochemiluminometric Assay and Immunoradiometric Assay for Differentiated Thyroid Cancer. A clinic-based hypertension management program comprising patient education, support, medication, and home BP monitoring was effective at reducing BP. Recent theories suggest that poor working memory (WM) may be the cognitive underpinning of negative symptoms in people with schizophrenia. The oral and physical manifestations as well as iron studies and anemia classification based on the mean and heterogeneity of red cell size were assessed. In the healthy nose, the main respiratory air stream occurs mainly in the middle of the airway, accompanied by a diffused pattern of turbulent flow on the surface of the nasal mucosa.

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Detection of qubit-oscillator entanglement in nanoelectromechanical systems. Case presentation included a clinical vignette with photographs, Oswestry Disability Index and Visual Analog Scale scores and imaging with radiographic measurements. The medical images to be fused are firstly decomposed into multiscale representations by the wavelet transform. We describe an innovative multimodality approach to tumor localization using preoperative PET-CT and intraoperative ultrasonography and describe cases in which this technique was used. The present study examined the potential contributions of dopamine and opioid signaling to these processes using two different decision-making tasks. Rural development agencies may potentially use the proposed method for a first screening of restoration interventions. K-distribution three-dimensional mapping of biological tissues in optical coherence tomography.

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All-oxide-based synthetic antiferromagnets exhibiting layer-resolved magnetization reversal. The effect of nutritional supplementation on quality of life in people living with HIV: a randomised controlled trial. This review article discusses nonpharmacological management of AP-FGID based on the current literature including systematic reviews, randomized controlled trials, cohort and case control studies. Acne is a multifactorial skin disorder frequently observed during adolescence with different grades of severity. Main laboratory studies were performed in all patients at the baseline and during the treatment. These include the amount of sunscreen applied and how it is spread over the skin. Nanoscale View of Dewetting and Coating on Partially Wetted Solids. The study was based on the Swedish Medical Birth Register between 1992 and 2010 and included 1,569,173 singleton pregnancies.

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Gastric and esophageal cancers: perspectives from a U.S.-Japan meeting. This chapter reviews the basis for our current use of radiation to treat high-grade gliomas, and addresses this model in the context of therapeutically resistant stem cells. Myc/Miz1-repressed genes encode proteins involved in cell adhesion and migration and include several integrins. In athletes with chronic patellar tendinitis, areas of abnormal signal intensity on MR imaging corresponded to degenerative pathologic changes consistent with angiofibroblastic tendinosis. Pharmacokinetics and pharmacodynamics of two different landiolol formulations in a healthy Caucasian group. These are the first reported cases of adiaspiromycosis in northern hairy-nosed wombats and the organism was associated with significant pathological changes. Compartmental modeling of zinc metabolism was performed by using tracer and mass data in plasma, urine, and feces collected over 6-14 d. Using different combinations of genetically modified mice, we demonstrate that Nrf2 activates the production, recycling, and release of glutathione and cysteine by suprabasal keratinocytes, resulting in protection of basal cells in a paracrine, glutathione/cysteine-dependent manner. A previous publication claimed that the radB gene called Pk-REC from Pyrococcus furiosus complemented an E. Comparison of methods for kinematic identification of footstrike and toe-off during overground and treadmill running.

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Innate function of house dust mite allergens: robust enzymatic degradation of extracellular matrix at elevated pH. Patients had a confirmed diagnosis of pemphigus vulgaris/foliaceus, bullous pemphigoid, epidermolysis bullosa acquisita, mucous membrane pemphigoid/cicatricial pemphigoid, or anti-p200 pemphigoid. Tetramethylenedisulfotetramine (tetramine, or TETS) is a highly toxic rodenticide that has been responsible for over 14,000 accidental and intentional poisonings worldwide. Structural requirements for palladium catalyst transfer on a carbon-carbon double bond. Effect of moderate alcohol consumption on fibrinogen levels in healthy volunteers is discordant with effects on C-reactive protein. After the closure of 7 unilateral eyes (right 3, left 4) with operation, the two kitten groups were fed for 12 weeks under a same visual environment. The Single Ventricle Reconstruction Trial represents the largest cohort of children with hypoplastic left heart syndrome ever assembled.

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