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Artagen (Naproxen)

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Artagen is used for short-term relief of pain, inflammation, and swelling in conditions that affect joints and muscles. It works by blocking chemical messengers in the brain that tell us we have pain. It can help relieve pain in conditions like rheumatoid arthritis and osteoarthritis.

Other names for this medication:
Aleve, Anaprox, Artagen, Arthopan, Movibon, Naprelan, Naprodom, Naproxen, Naxdom, Pacinac, Xenadom, Xenar, Xenobid

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Also known as: Naproxen


Artagen (naproxen) is a nonsteroidal anti-inflammatory drug (NSAID). Naproxen works by reducing hormones that cause inflammation and pain in the body.

Artagen is used to treat pain or inflammation caused by conditions such as rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, tendinitis, bursitis, gout, or menstrual cramps.

Artagen delayed-release tablets are slower-acting forms of naproxen that are used only for treating chronic conditions such as arthritis or ankylosing spondylitis. These forms of naproxen will not work fast enough to treat acute pain.


This section provides information on the proper use of a number of products that contain naproxen. It may not be specific to EC Artagen. Please read with care.

For safe and effective use of this medicine, do not take more of it, do not take it more often, and do not take it for a longer time than ordered by your doctor. Taking too much of this medicine may increase the chance of unwanted effects, especially in elderly patients.

This medicine should come with a Medication Guide. Read and follow these instructions carefully. Ask your doctor if you have any questions.

When used for severe or continuing arthritis, this medicine must be taken regularly as ordered by your doctor in order for it to help you. This medicine usually begins to work within one week, but in severe cases up to two weeks or even longer may pass before you begin to feel better. Also, several weeks may pass before you feel the full effects of this medicine.

Check with your doctor first before changing dosage forms (eg, tablets, suspension). These forms are very different from each other.

Swallow the delayed-release tablet whole. Do not crush, break, or chew it.

If you are using the suspension, shake it gently before using it. Use the marked measuring cup included in the package to measure the dose.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For naproxen (eg, Artagen®) tablet and oral suspension dosage forms: For rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis: Adults—At first, 250 milligrams (mg) (10 milliliters (mL)/2 teaspoonfuls), 375 mg (15 mL/3 teaspoonfuls), or 500 mg (20 mL/4 teaspoonfuls) 2 times a day, in the morning and evening. Your doctor may adjust your dose as needed. However the dose is usually not more than 1500 mg per day. Children 2 years of age and older—Dose is based on body weight and must be determined by your doctor. The dose is usually 5 milligrams (mg) per kilogram (kg) of body weight 2 times a day. Children younger than 2 years of age—Use and dose must be determined by your doctor. For acute gout: Adults—750 milligrams (mg) for the first dose, then 250 mg every 8 hours until the attack is relieved. Children—Use and dose must be determined by your doctor. For naproxen controlled-release tablet (eg, Naprelan®) dosage form: For rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis: Adults—At first, 750 milligrams (mg) (taken as one 750 mg or two 375 mg tablets) or 1000 mg (taken as two 500 mg tablets) once a day. Your doctor may adjust your dose as needed. However the dose is usually not more than 1500 mg (taken as two 750 mg or three 500 mg tablets) per day. Children—Use and dose must be determined by your doctor. For bursitis, tendinitis, menstrual cramps, and other kinds of pain: Adults—At first, 1000 milligrams (mg) (taken as two 500 mg tablets) once a day. Some patients may need 1500 mg (taken as two 750 mg or three 500 mg tablets) per day, for a limited period. However, the dose is usually not more than 1000 mg per day. Children—Use and dose must be determined by your doctor. For acute gout: Adults—1000 to 1500 milligrams (mg) (taken as two to three 500 mg tablets) once a day for the first dose, then 1000 mg (taken as two 500 mg tablets) once a day until the attack is relieved. Children—Use and dose must be determined by your doctor. For naproxen delayed-release tablet (eg, EC-Artagen®) dosage form: For rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis: Adults—At first, 375 or 500 milligrams (mg) 2 times a day, in the morning and evening. Your doctor may adjust the dose as needed. However, the dose is usually not more than 1500 mg per day. Children—Use and dose must be determined by your doctor. For naproxen sodium (eg, Anaprox®, Anaprox® DS) tablet dosage form: For rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis: Adults—At first, 275 or 550 milligrams (mg) 2 times a day, in the morning and evening. Your doctor may adjust the dose as needed. However, the dose is usually not more than 1500 mg per day. Children—Use and dose must be determined by your doctor. For bursitis, tendinitis, menstrual cramps, and other kinds of pain: Adults—550 milligrams (mg) for the first dose, then 550 mg every 12 hours or 275 mg every 6 to 8 hours as needed. Your doctor may adjust the dose as needed. However, the dose is usually not more than 1375 mg per day. Children—Use and dose must be determined by your doctor. For acute gout: Adults—825 milligrams (mg) for the first dose, then 275 mg every 8 hours until the attack is relieved. Children—Use and dose must be determined by your doctor.


If you overdose Artagen and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Artagen overdosage: excessive fatigue, heartburn, lightheadedness, confusion, feeling drowsy, problems with breathing, problems with urination, vomiting, pain of stomach, dyspepsia.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed EC-Artagen dosage information

Side effects

The most common side effects associated with Artagen are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Artagen may also cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are using Artagen, especially in older adults.

You should not use Artagen if you are allergic to naproxen, or if you have ever had an asthma attack or severe allergic reaction after taking aspirin or an NSAID.

Ask a doctor before giving naproxen to a child younger than 12 years old.

Ask a doctor or pharmacist if it is safe for you to use this medicine if you have:

heart disease, high blood pressure, high cholesterol, diabetes, or if you smoke; a history of heart attack, stroke, or blood clot; a history of stomach ulcers or bleeding; asthma; liver or kidney disease; fluid retention: or if you take aspirin to prevent heart attack or stroke.

If you are pregnant, you should not take Artagen unless your doctor tells you to. Taking a NSAID during the last 20 weeks of pregnancy can cause serious heart or kidney problems in the unborn baby and possible complications with your pregnancy.

It may not be safe to breastfeed while using Artagen. Ask your doctor about any risk.

Artagen is not approved for use by anyone younger than 2 years old. Do not give this medicine to a child without medical advice.

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We describe a 41-year-old female with SLE who had multiple relapses and remissions of her disease during the last 20 years and developed a right eyelid swelling. Preliminary Study on Physicochemical and Biochemical Stress Markers at Poultry Slaughterhouse. The adverse influence of ESBL producers on clinical outcomes was presented with respect to adults with community-onset EKP bacteremia. Though there may be a substantial benefit from lumbar fusion in the SOT population, judicious patient selection is of paramount importance. Metchnikoff-Schaumann bodies in the golden hamster inoculated with BCG. We conclude that deficits in SST interneurons represent a contributing cellular pathology and therefore a promising target for normalizing altered inhibitory function in MDD and other disorders with reduced SST cell and GABA functions. Considering the potential advantage of hypofractionated radiotherapy to decrease the treatment burden and increase the quality of remaining life, we suggest that more attention should be paid to hypofractionated radiotherapy. This was used in a leave-one-out cross-validation to train weights that optimized the rankings of images in the database in terms of similarity to query images.

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Feeding on plant material is common among animals, but how different animals overcome the dietary deficiencies imposed by this feeding strategy is not well understood. Anemia is prevalent at pediatric intensive care unit (PICU) admission and incident during PICU stay, but little is known about anemia at PICU discharge . In the telencephalic auditory centre, on the other hand, no particular region differed in either immunoreactivity or cytochrome oxidase activity. The reusability of gesture is improved by establishing the state transition model. The use of statistical parametric mapping (SPM96) as a decision aid in the differential diagnosis of dementia using 99mTc-HMPAO SPECT. Information acquired included demographic and disease activity data, treatment options, and obstetrical and breastfeeding data. Stem cell function depends on finely tuned interactions of signaling molecules and transcription factors, which are not well defined in dogs. diskImageR: quantification of resistance and tolerance to antimicrobial drugs using disk diffusion assays. Calcific aortic valve disease (CAVD) is the most common valvular heart disease and likely evolves from inflammatory pre-conditions in the valve.

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The data obtained were compared statistically and qualitatively, individually and between the different groups. Both ofloxacin-placebo myambutol treatment and tobramycin-erythromycin treatment were more effective than no treatment in sterilizing the external ocular adnexa. A CR has the potential to impact on the patient pathway, enabling quicker times from DTT to treatment. To analyze the predictive ability of total tumor size in lung adenocarcinoma subtype and lymph node involvement. It also plays a role as an antioxidant agent against reactive oxygen species (ROS) generated by various substances.

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Increase in nonhepatic diagnoses among persons with hepatitis C hospitalized for any cause, United amoxil 500mg dosage States, 2004-2011. By studying these racial dissimilarities in a multi-ethnic society, it allows us greater understanding of disease epidemiology, natural history and pathogenesis affected by ethnicity. Modifying disease drugs can delay convertion to clinically defined multiple sclerosis, therefore, identify patients at a higher risk of convertion is important. These findings indicate that TRPV4 upregulation in vascular endothelial cells contributes to the progression of colonic inflammation via the activation of vascular permeability. Approach to issuing animal test certificates for veterinary medicines. The estimated global HMPAO uptake did not differ between the two conditions indicating a similar overall cortical activity. The presence of complexing anions is also known to affect the binding of these metals in soils. Ablation of complex fractionated electrograms is useful for catheter ablation of persistent atrial fibrillation: Protagonist point of view.

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