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Aridus (Aripiprazole)

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Aridus comes as a tablet, a solution (liquid), an orally disintegrating tablet (tablet that dissolves quickly in the mouth) to take by mouth. It is usually taken once a day with or without food. Apriprazole also comes as a tablet that contains a sensor device to take by mouth to be used in adults to provide information about how the medication is taken.

Other names for this medication:
Apicord, Aridus, Arifril, Arilan, Arinex, Aripat, Aripicon, Aripiprazole, Aripra, Arpicin, Asprito, Biliff, Elrip, Pipra, Rizotal, Schizopra

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Also known as: Aripiprazole


The Aridus Maintena brand of aripiprazole is used to treat schizophrenia and bipolar I disorder (manic depression) in adults. The Aristada brand of Aridus Maintena is for use only in treating schizophrenia in adults.


This section provides information on the proper use of a number of products that contain aripiprazole. It may not be specific to Aridus Discmelt. Please read with care.

Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. To do so may increase the chance of side effects.

This medicine should come with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

If you are using the orally disintegrating tablet, make sure your hands are dry before you handle the tablet. Do not open the blister pack that contains the tablet until you are ready to take it. Remove the tablet from the blister pack by peeling back the foil, then taking the tablet out. Do not push the tablet through the foil. Do not break or split the tablet. Place the tablet in your mouth. It should melt quickly. After the tablet has melted, you may swallow or take a sip of water.

Swallow the tablets whole. Do not break, crush, or chew them.

Aridus Mycite® has a sensor in the tablet, which helps track it inside the stomach or bowels. The Aridus Mycite® System comes with a patch (wearable sensor), a smartphone application (app), and a web-based portal. Follow your doctor's instructions on how to use the medicine.

The Aridus Mycite® tablet is usually detected within 30 minutes after you take it, but there may be a delay of more than 2 hours for the smartphone app and web portal to detect that you have taken the medicine, and sometimes it might not be detected at all.

To apply the Aridus Mycite® patch:

The app will tell you when to apply or remove the patch. It should be changed weekly or sooner as needed. Place the patch to the left side of your body just above the lower edge of your rib cage. Do not put the patch in areas where the skin is scraped, cracked, inflamed, or irritated, or near the area where you had removed the previous patch. The app will help you place the patch in the correct location. You may keep the patch on when showering, swimming, or exercising.

Aripiprazole may be taken with or without food. If your doctor tells you to take it a certain way, follow your doctor's instructions.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage forms (tablets and orally disintegrating tablets): For bipolar mania: Aridus® and Aridus Discmelt®: Adults—At first, 15 milligrams (mg) once a day. When it is given with lithium or valproate, the starting dose is 10 to 15 mg once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 30 mg per day. Children 10 years of age and older—At first, 2 mg once a day. The dose will be gradually increased to 10 mg once a day. Your doctor may adjust your dose again as needed. However, the dose is usually not more than 30 mg per day. Children younger than 10 years of age—Use and dose must be determined by your doctor. Aridus Mycite®: Adults—At first, 15 milligrams (mg) once a day. When it is given with lithium or valproate, the starting dose is 10 to 15 mg once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 30 mg per day. Children—Use and dose must be determined by your doctor. For depression: Adults—At first, 2 to 5 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 15 mg per day. Children—Use and dose must be determined by your doctor. For irritability in children with autistic disorder: Children 6 to 17 years of age—At first, 2 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 15 mg per day. Children younger than 6 years of age—Use and dose must be determined by your doctor. For schizophrenia: Aridus® and Aridus Discmelt®: Adults—At first, 10 to 15 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 30 mg per day. Children 13 to 17 years of age—At first, 2 mg once a day. The dose will be gradually increased to 10 mg once a day. Your doctor may adjust your dose again as needed. However, the dose is usually not more than 30 mg per day. Children younger than 13 years of age—Use and dose must be determined by your doctor. Aridus Mycite®: Adults—At first, 10 to 15 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 30 mg per day. Children—Use and dose must be determined by your doctor. For Tourette's disorder: Children 6 to 18 years of age—At first, 2 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 20 mg per day. Children younger than 6 years of age—Use and dose must be determined by your doctor.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include drowsiness, vomiting, aggression, confusion, tremors, fast or slow heart rate, seizure (convulsions), weak or shallow breathing, fainting, or coma.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Aridus Discmelt dosage information

Side effects

The most common side effects associated with Aridus are:

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To assess whether a similar interaction occurs with a more commonly used and less hepatotoxic macrolide antibiotic, erythromycin, we evaluated methylprednisolone pharmacokinetics before and after a 1 wk course of erythromycin base in nine adolescent patients with chronic asthma. The highly predominant motor presentation, and the higher male prevalence as well as the apparent concentration in Northern China may be due to observational bias. The behaviors and fate of polycyclic aromatic hydrocarbons (PAHs) in a coking wastewater treatment plant. We describe the effect on the neonate of administration of rituximab to a woman with idiopathic thrombocytopenic purpura (ITP). In this Letter we present a nonperturbative but convergent series of the effective action. Altered expression patterns cause progression of multiple diseases inside an organism. This moderate elevation was observed less frequently with Amvisc than with Healon, and may be attributed to the lower viscosity of Amvisc. The source of hemolysin-forming cells in irradiated mice given bone marrow and thymus or thoracic duct lymphocytes.

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The essential feature of the MIrizzi syndrome is partial common hepatic duct obstruction due to an impacted cystic duct stone. A rapid and sensitive method for the determination of proteins is proposed with a coupled reagent of o-phthalaldehyde and sulfanilic acid by measuring the light scattering (LS) signals with a common spectrofluorometer. Bimatoprost lacks effects on the FP receptor but may interact with the FP-altFP receptor heterodimer to induce alterations in second messenger signalling. A firm pillow which allows air and fluid to pass through it is best, and is probably superior to a mattress covered with a mackintosh and a sheet.External obstruction to respiration could be a contributory factor in some cases of cot death. Coagulation and fibrinolysis profiles of naturally menopausal women receiving conjugated estrogens (0.625 or 1.25 mg for 21 of 28 days) and medroxyprogesterone acetate (10 mg for seven of 28 days) for 18 months were compared with those of similar women receiving no hormone therapy. Genetic polymorphism of serum complement components in the chimpanzee.

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A questionnaire measure of emotional control was developed to evaluate the extent to which individuals report controlling anger, anxiety and depressed mood. We recently reported that polysialic acid (PSA) attached to the neural cell adhesion molecule (NCAM) is one of the cellular antigens for HIgM12. Radiation regenerated by such a filter reaches about 1250 which exceeds the safe value for ocular exposure. Research specific to CKD is required to develop systematic and comprehensive information on the end-of-life care needs and the quality of end-of-life care for patients with CKD, to describe the effectiveness of existing end-of-life care strategies in CKD (including cost-effectiveness), to identify areas that should be priorities for improvement and ultimately to develop innovative strategies for improving the end-of-life care for patients dying with CKD. In this case report, we describe for the first time in Korea a case of early stage hypopharyngeal carcinoma that was successfully treated by endoscopic submucosal dissection with a review of literature. A highly conserved glutamic acid residue of transmembrane helix III in subunit I, E107, was suggested to be part of a transmembrane pathway delivering protons from the cytoplasm to the oxygen-reducing site. Esophageal wall involvement in cardiac cancer--with special reference to the case with radiographical presentation of cardiac achalasia. In women undergoing midurethral sling revision for mesh exposure, complete sling removal resulted in higher recurrent stress incontinence compared to partial sling removal. Donor case workshops actively engage participants with diverging background and experience in an informal, secure and enjoyable setting.

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Effects of temperature on bovine sperm acrosome reaction, oocyte maturation, hyaluronic acid production by cumulus cells and in vitro fertilization were studied. The HL7 message standard is widely adopted to cover all data exchanges in the system. ASTRAL, DRAGON and SEDAN scores predict outcome of acute ischaemic stroke patients with higher accuracy compared to physicians interested in stroke. We have previously demonstrated that adrenaline (AD) is released into the circulation during acute myocardial infarction and is associated with a more severe clinical course. Unlike most previous studies of mora-timing in Japanese, this article investigates timing in spontaneous speech. Preferred provider organizations (PPOs) have been under speculation by both the business community and the health care industry in their guests for ways to control health care costs since the first PPO sprang up less than a decade ago. The factor is stable at pH 2.0 and stable at 56 degrees C, but is inactivated by 2-mercaptoethanol.

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The purpose of this paper is to clarify the definition and anatomic characteristics of pulmonary atresia with ventricular septal defect. Inhibiting NMT functions to control malignancy is a novel approach in the area of anticancer drug design and there are rapidly expanding discoveries of synthetic NMT inhibitors as potential chemotherapeutic agents to be employed in the warfare against cancer. Oestrogen-induced endometrial hyperplasia in gonadal dysgenesis. Time trends in ectopic pregnancy over a decade--a retrospective hospital-based study. However, the range of targets detectable by functional DNAs is limited at the current stage. A REPORT OF AN INVESTIGATION INTO THE QUALITY OF PREPARATIONS OF DRUGS INTENDED FOR INJECTION. Community nursing interventions did not differ greatly by disease groups.

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Three specimens with a clearly elevated level (0.96, 1.11 and 2.51 nmol/l) were observed. Peripheral sensory afferents in the hand activate both excitatory and inhibitory intracortical circuits to potentially facilitate and prune descending motor commands. Little is known about the beliefs and attitudes that promote and maintain douching practices. The association between fructosamine-3 kinase 900C/G polymorphism, transferrin polymorphism and human herpesvirus-8 infection in diabetics living in South Kivu. Seventeen O(6)-alkylguanine-DNA alkyltransferase (AGT) mutants highly resistant to O(6)-benzylguanine (BG) were identified previously by screening 8 million variants, using genetic complementation in Escherichia coli. How productivity is perceived by an organization may well determine whether it will be achieved, according to a new survey of industrial engineers, whose day-to-day work is aimed at productivity improvement. Transureteroureterostomy with cutaneous ureterostomy for permanent urinary diversion. For example, the expression of phorsphorylated protein kinase C (PKC) delta, p21 increased, while that of cyclin D1/cyclin-dependent kinase (CDK) 4, p-Rb decreased. Also BMI and region were found to be associated with dioxin activity levels. The aim of the present study was the monitoring of the redox status of runners participating in a mountain ultra-marathon race of 103 km.

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Dose-effect relationship of chromosome aberrations induced by 23 MeV alpha particles in human lymphocytes. The mechanism of block to polyspermy in Rhodeus eggs is discussed. Tonsillar tuberculosis and its relation to pulmonary tuberculosis. Follicular dendritic cells and tingible body macrophages are found in conventionally raised euthymic and athymic rats, but not in germ-free rats. Novel application of EEG source localization in the assessment of the penumbra. The factors that regulated macrophage effector functions, however, were different from those that induced colony formation, and could be distinguished from CSF by Sephadex gel chromatography or heat sensitivity. To be able to counter the increasing shortage of general practitioners (GPs) in many countries, it is crucial to remain up-to-date with the decisive reasons why young physicians choose or reject a career in this field. The predictive ability of the generated models was validated using different statistical metrics, and similarity-based coverage estimation was carried out to define applicability boundaries. It was found that in anura and shark the fraction H1a resembled the histone 5 of birds in its N-terminal half part of the molecule. ON COXSAKIE B5 EPIDEMICS OBSERVED IN 2 HOMES FOR INFANTS DURING ADMINISTRATION OF LIVE POLIOVACCINE.

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Autoradiographic evidence for the selective enhancement of nucleolar ribonucleic acid synthesis in prostatic nuclei by testosterone. There is a weaker genetic link between anxiety sensitivity and sexual distress and between sexual distress and FSD. On average, participants preferred an individual walking program that was coached, asked them to engage in one longer bout multiple times per week, and was provided in home. The effect of selective serotonin reuptake inhibitors in healthy first-degree relatives of patients with major depressive disorder - an experimental medicine blinded controlled trial. An LTR Retrotransposon-Derived Gene Displays Lineage-Specific Structural and Putative Species-Specific Functional Variations in Eutherians. Pitx3 activation of TH promoter activity appears to be cell-dependent suggesting that Pitx3 action may be modulated by other(s) regulatory mechanism(s) and factor(s). These individuals could benefit from further evaluation with iron phenotyping and HFE mutation analysis.

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Guillain-Barre syndrome complicated by hypertension and ileitis. Furthermore, western blotting was performed to investigate the protein expression levels of matrix metalloproteinases (MMPs) and mitogen-activated protein kinase. Expression of the TRAP isoenzyme was found in nearly rocaltrol dose all cases of hairy cell leukemia, but also in a significant number of other B-cell or monocyte derived malignancies. The applicant will conduct postmarketing clinical trials to demonstrate clinical benefit, for example, survival prolongation. In patients with cardiovascular risk factors, diagnosis of LVAB is a challenge due to the similarities in symptoms with acute coronary syndrome. Intra-operatively all 4 parathyroid glands and local lymph nodes showed necrotising granulomas with occasional acid-fast bacilli, pathognomonic of tuberculosis (TB). This condition should be considered whenever the right lobe of the liver is hypoplastic and the gallbladder cannot be visualized on hepatobiliary scans or oral cholecystograms. Survey of Chinese Medicine Students to Determine Research and Evidence-Based Medicine Perspectives at Pacific College of Oriental Medicine. By introducing guest molecules coronene (COR), we for the first time achieved novel triangle-shaped COR trimers on liquid/highly oriented pyrolytic graphite (HOPG) interface in both honeycomb network and the disordered structure.

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Although NAC treatment down-regulated inflammatory mediators in lungs during AP it did not prevent leukocyte infiltration, which could be responsible for maintaining the lung injury. The conditions suggest that polymorphism will be more likely in more variable environments while unlikely in constant environments. Data indicated that high serum Epo levels primarily affect betaminor-globin mRNA accumulation in reticulocytes. Magnetic resonance imaging delineated the extent of the tumors and helped in preoperative planning. Results of treating mastodynias and mastopathies with percutaneous progesterone. The mechanism by which the histone deacetylase (HDAC) inhibitor trichostatin A inhibits epidermal growth factor (EGF)-induced human 12(S)-lipoxygenase expression was studied. EFFECT OF WATER SOLUBLE VITAMINS AND THEIR ANALOGUES ON GROWTH OF CANDIDA ALBICANS. The expression of various apoptotic and antiapoptotic markers in the tissues were studied by immunohistochemistry and Western blotting. The impact of labeling on rejection of the mentally ill: an experimental study.

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They have a wide range of applications in medicine, electronics, biomaterials, and energy production. In addition to completing a number of standardized questionnaires assessing adjustment to chronic pain, participants underwent a submaximal effort tourniquet procedure. The development of the angioarchitecture of the organum vasculosum laminae terminalis (OVLT) is described at the light-microscopical level in connection with the formation of the brain ventricles in rat embryos (gestational day 12 through day 21) injected with India-ink via the umbilical vessels. The patient was admitted to the emergency unit after head trauma at 11 months of age. Some observations on the role of type 1 fimbriae in Escherichia coli autoflocculation. RESEARCH ON THE EFFECTS OF ORANGE JUICE ON THE SURVIVAL OF RATS SUBJECTED TO VITAMIN MULTI-DEFICIENCIES AND ALTERNATING REPLETIONS. We show that these analytical predictions are in good agreement with numerical results for sufficiently large networks and study finite-size effects in detail. Utilization review in diagnostic imaging: can quality be cost effective?. We show that the period adding cascades appearing in bubbling from a nozzle submerged in a viscous liquid can be reproduced by a simple model, based on some hydrodynamical principles, dealing with the time evolution of two variables, bubble position and pressure of the air chamber, through a system of differential equations with a rule of detachment based on force balance.

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The effectiveness of these oximes in restoration of VX-inactivated ChE in vivo offers an explanation as to why conventional atropine/oxime therapy is so effective against VX intoxication. ESOD activity eventually declined at only one-third to one-seventh of the rate shown by plasma copper, the difference being particularly marked in severely depleted lambs. The multiple breath wash-out technique (MBW) that measures lung clearance index (LCI) and functional residual capacity (FRC) may be more sensitive than spirometry for identification of early obstructive airways disease. Calcium stones: the difference between provigil medication generic oxalate and phosphate types. Hypovolemic hyponatremia at the onset of severe ischemic stroke as a predictor of adverse outcome. This means that the phase of the wave, which propagates inside the guide, does not suffer sensible variation in the passage between X- and K(u)-bands. Additionally, mm-LDL stimulated the transport of Cy3-labeled activating transcription factor 6 (ATF6), a key sensor to the unfolded protein response (UPR), from cytoplasm into nucleus. Successful Eradication of Hepatitis C Virus by Interferon-Free Regimens in Two Patients with Advanced Liver Fibrosis following Kidney Transplantation. In the present contribution, an automated screening method for studying ligand interactions of selected sorbent materials with pepsin - a protein of the protease family - was developed. Sacral neuromodulation outcomes in patients with urge urinary incontinence and concomitant urge fecal incontinence.

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Students were able to engage in necessary skills for their future nursing practice. Although the antibodies alone (IgM) did not have an opsonizing effect, in the presence of such antibodies uptake and ingestion of liposomes by mouse peritoneal macrophages was enhanced 5- to 10-fold by addition of complement. A secondary analysis of a randomized-controlled trial was conducted to examine the role of family-based intervention versus usual social work care (care as usual) in supporting HIV status disclosure within families in Rwanda. Pathogenesis of cardiac insufficiency in elderly and aged patients with hypertension. The perceived dominance of percepts within a rival pair of images can be influenced by emotional content, with emotional images dominating over neutral images. Awareness of disease is an important aspect of asthma management. Distinct hydration behaviors were observed for the four types of bread. The efficiency of wound dressing materials as a barrier to secondary bacterial contamination. Few data are available for EGFR-mutated localized NSCLC, as routine biological profiling is not recommended.

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