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Arachitol (Calcitriol)
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Arachitol

Arachitol is a hormonally-active, synthetic vitamin D analog prescribed to treat hypocalcemia, osteoporosis, and the prevention of corticosteroid-induced osteoporosis. Systemic Arachitol is FDA indicated to control hypocalcemia in patients on chronic renal dialysis, secondary hyperparathyroidism in those with chronic kidney disease not yet on dialysis, and hypocalcemia in patients with hypoparathyroidism and pseudohypoparathyroidism.

Other names for this medication:
Alcee, Alfabond, Apcical, Biocal, Bonetuf, Calbory, Calbovic, Calcigra, Calcit, Calfa, Calgel, Caltive, Caltop, Calzem, Carcal, Cholical, Dmcal, Fovit, Koncal, Lctrol, Minroset, Osteobel, Ostriol, Rical, Ritoca, Romical, Solbiocal, Sunmic, Tobalt, Vitalpha

Similar Products:
Cycrin, Fulvicin, Prevacid, Lozol, Cordarone, Paral, Anafranil, Befine, Etova, Deczole, Adelphan, Actimol,

Also known as: Calcitriol

Description

Generic Arachitol is a synthetic vitamin D analog which is active in the regulation of the absorption of calcium from the gastrointestinal tract and its utilization in the body. The two known sites of action of Generic Arachitol are intestine and bone. Generic Arachitol receptor-binding protein appears to exist in the mucosa of human intestine. Additional evidence suggests that Generic Arachitol may also act on the kidney and the parathyroid glands. Generic Arachitol is the most active known form of vitamin D3 in stimulating intestinal calcium transport. In acutely uremic rats Generic Arachitol has been shown to stimulate intestinal calcium absorption. The kidneys of uremic patients cannot adequately synthesize Generic Arachitol, the active hormone formed from precursor vitamin D. Resultant hypocalcemia and secondary hyperparathyroidism are a major cause of the metabolic bone disease of renal failure. However, other bone-toxic substances which accumulate in uremia (eg, aluminum) may also contribute. The beneficial effect of Generic Arachitol in renal osteodystrophy appears to result from correction of hypocalcemia and secondary hyperparathyroidism. It is uncertain whether Generic Arachitol produces other independent beneficial effects. Arachitol is also known as Calcitriol. Generic Arachitol treatment is not associated with an accelerated rate of renal function deterioration. No radiographic evidence of extraskeletal calcification has been found in predialysis patients following treatment. The duration of pharmacologic activity of a single dose of calcitriol is about 3 to 5 days. Generic name of Generic Arachitol is Calcitriol. Brand name of Generic Arachitol is Arachitol.

Dosage

Generic Arachitol is available in capsules (0.25 mcg) and liquid form. Capsules must be swallowed whole. Do not crush or chew them. If you are prescribed the liquid form, use as directed. Follow dosing instructions closely. Do not take this medication with mineral oil or magnesium containing antacids which may reduce its effects. Foods rich in vitamin D include: fortified dairy products, eggs, sardines, cod liver oil, chicken livers and fresh-water fish. Vitamin D is also obtained from periodic exposure to the sun. It is important to maintain a well-balanced diet while taking this medication. Calcium supplements may be recommended in addition to this medication. If you want to achieve most effective results do not stop taking Generic Arachitol suddenly.

Overdose

If you overdose Generic Arachitol and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Arachitol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

It is especially important that you receive the right amounts of vitamins so that your baby will also get the vitamins needed to grow properly. Infants who are totally breast-fed and have little exposure to the sun may require vitamin D supplementation. However, taking large amounts of a dietary supplement while breast-feeding may be harmful to the mother and/or baby and should be avoided.

Only small amounts of alfacalcidol, calcifediol, calcitriol, or dihydrotachysterol pass into breast milk and these amounts have not been reported to cause problems in nursing babies.

It is not known whether doxercalciferol or paricalcitol passes into breast milk. Be sure you have discussed the risks and benefits of the supplement with your doctor.

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Identification of alleles of carotenoid pathway genes important for zeaxanthin accumulation in potato tubers. Although a favorable effect on peak VO2 was observed on FCM, compared with standard of care in the primary analysis, this effect was highly sensitive to the imputation strategy for peak VO2 among patients who died. A pilot phase II study of ofatumumab monotherapy for extranodal marginal zone B-cell lymphoma of the mucosa-associated lymphoid tissue (MALT) lymphoma. Nuclear run-on transcription assay in isolated luminal epithelial cell nuclei showed that c-fos gene transcription increased rapidly in the uterus after estradiol stimulation. Extracting nuclei is one of the most actively studied topic in the digital pathology researches. The purpose of the present study was to evaluate differences in the AMP-activated protein kinase (AMPK) phosphorylation sites in cardiac hypertrophy induced by L-thyroxine and angiotensin (Ang) II. The prevention by neurovegetative block of shock phenomena caused by tourniquet constriction of blood circulation. Although the differential expression of several lncRNAs is suggestive of a role in epidermal differentiation, their biological functions remain to be elucidated. Anticoagulation with warfarin or dabigatran for 3 to 4 months does not promote the formation of CMBs in aged APP23 mice.

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Incidence of coronary disease in obliterating arteriosclerosis and thromboangiosis. Because the AP-3-oligomer also contains an overlapping NF-kappa B-like site, the role of NK-kappa B proteins in regulating transcription from this multimerized oligonucleotide was investigated. In relatively healthy MHD patients, KDQOL scores are usually decreased in those with anxiety and/or depression but are usually normal in those without anxiety or depression. Thus, characterization of SPG dynamics is essential for understanding multicentennial variations of the seasonal cycle in the European/North Atlantic sector. Medline library database was searched, focusing on stem cells, osteoblast differentiation, bone growth factors and bone tissue engineering. Proliferative Melanocytic Nodule on Small Congenital Nevus During Treatment With Etanercept. A computer program linking physiologically based pharmacokinetic model with cancer risk assessment for breast-fed infants. Occasionally, collateral circulation has the potential to maintain adequate perfusion to the posterior fossa in severe cases of posterior circulation occlusion and diffuse intracranial atherosclerotic disease.

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UK prevalence and service use data were taken from policy and research literature, as well as national data sets and reports. The mechanisms involved encompass a chronic systemic inflammatory state, insulin resistance, and a potential, direct infection of the vascular endothelium. The UHC-sponsored panel included eight physicians (board certified in critical care, hematology, immunology, neurology, oncology, pediatrics, or rheumatology) and two hospital pharmacists. Despite the similar cysteine content in all samples, thiol accessibility in O. To determine how well conventional radiographic findings can predict the presence of dural ectasia in Marfan patients. Rats on day 2 of pregnancy were untreated or treated with 10 micrograms of E2 and the oviducts were extracted at 30, 180 and 360 min later and used to isolate RNA. There is reason, however, to be suspicious that elements in the tail that are located immediately adjacent to the motor region influence, or in some way contribute to, normal motor activity. Activated caspase-3 immunohistochemistry was used to quantify apoptotic death in controls and midazolam-treated subjects.

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Using mouse model of Citrobacter rodentium infection, we investigated the role of PFOS on intestinal immunity. The aim of this article is to provide a review of PARPi function in DNA damage repair and synthetic lethality and to demonstrate how these mechanisms can be exploited to provide new PARPi-based therapies to patients with solid tumors. 3-Aminobenzamide (ABA), an inhibitor of PARP, spared the depletion of NAD and ATP and prevented the cell killing. Atrial fibrillation (AF) is the most common cardiac arrhythmia in clinical settings known to impair cardiac function. Our research team has demonstrated that lumbosacral spinal cord epidural stimulation (scES) and activity-based training can progressively promote the recovery of volitional leg movements and standing in individuals with chronic clinically complete SCI. We investigated the incidence, reversibility, and prognosis of conduction disorders requiring permanent pacemaker implantation in patients with degenerative aortic stenosis after isolated aortic valve replacement. This study explored the relationship between the glycated hemoglobin (HbA1c) level in patients with or without diabetes mellitus and future risks of cardiovascular disease and death. However, this technology raises crucial questions regarding its nature and development perspective. Trigeminal input to the ascending activating system is important for the maintenance of arousal and may affect the discharge of the noradrenergic neurons of the locus coeruleus (LC), whose activity influences both vigilance state and pupil size, inducing mydriasis. QVA149 Improves Lung Function, Dyspnea, and Health Status Independent of Previously Prescribed Medications and COPD Severity: A Subgroup Analysis from the SHINE and ILLUMINATE Studies.

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This study tested the hypothesis on implication of NO in shaping the electrical abnormalities provoked by stretch of the right atrial myocardium in rat via a mechanism engaging a signaling cascade, where NO plays a significant role. This combinatorial strategy shows significant increase in the treatment efficacy over monotherapy in the experimental validation using patient-derived xenograft platforms in vitro and in vivo. These granulocytes have a relatively short half-life (6-8 h) in the blood, and as a result of the cytotoxic nature of their contents, it is critical that there are mechanisms in place for the efficient clearance of these effete cells from the circulation. Our analyses indicate that more interdomain transfers occurred before the development of a sequestered germline, consistent with the hypothesis that this feature is an obstacle to LGT. Production of polyclonal antisera that recognize and distinguish between the extracellular domains of neuronal nicotinic acetylcholine receptor subunits.

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However, he died from congestive heart failure and pneumonia in May of 1993. The assessment of eye lens doses for workers during interventional radiology (IR) procedures was performed using a new eye lens dosemeter. Correlates of incorrect condom use among depressed young women: an event-level analysis. There were significant SES disparities in health outcomes over the 11-year study period. The demonstration of the myelin alterations in the living cerebral tissue exposed to serum during incubation may contribute to understanding the pathogenesis of multiple sclerosis. This study aimed to evaluate the possible impact of age on: i) serum allergen-specific IgE levels in a large sample of subjects, and ii) AR symptom severity in a group of mono-allergic patients. Floral symmetry can be grouped into three main categories: asymmetry, bilateral symmetry and radial symmetry, characterised by zero, one, and multiple planes of symmetry, respectively.

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Impact of comorbid mental health needs on racial/ethnic disparities in general medical care utilization among older adults. Effective mangrove conservation requires the determination of species identity, management units, and genetic structure. Cardiac involvement is a leading cause of death from sarcoidosis. Adapting educational tools to meet user needs is a critical aspect of translating research evidence into best clinical practices. However, detailed studies of DNA repair in the G2 phase of the cell cycle have been hampered by technical limitations. Partial Pulpotomy in Immature Permanent Molars After Carious Exposures Using Different Hemorrhage Control and Capping Materials. The gene expression library of MM (accession number: GSE6477) was downloaded from the Gene Expression Omnibus (GEO) database. cholerae O139 produce cholera toxin and cause cholera, other serogroups can cause gastroenteritis, open wounds infection, and septicaemia. The presented case highlights the benefits of computed tomography (CT) in the diagnosis and surgical evaluation of this disorder. Distribution of p21ras during primary palate formation of non-cleft and cleft strains of mice.

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Osteogenic cell signaling could be also influenced by scaffold mechanical properties such as scaffold rigidity and dynamic relationships between the cells and their extracellular matrix. A two-compartment model is used as a fit to the uptake data of the thyroid and to estimate the activity in the blood-pool. Evaluated outcome parameters included corneal sensibility, improvement in best-corrected visual acuity, blink reflex, donor deficit, synesthesia, long-term corneal health, several psychosocial measures, and risperdal dose in children overall patient satisfaction. We evaluated the effectiveness of synthetic adrenocorticotropic hormone (ACTH) therapy without tapering in treating patients with West syndrome. In this series, complications were associated with delayed involvement of plastic surgeons. Emerging biomarkers have the potential to improve diagnosis and monitoring but further study is required to determine efficacy and validate clinical utility.

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Participants consisted of 8971 students from 173 neighbourhoods across Canada. Desalination has been considered as an essential way to solve water stress all over the world. Management of stroke patients in a specialised stroke unit hastens recovery and is associated with a sustained reduction in mortality. This case report presents the clinical use of a resin nanoceramic CAD/CAM restoration of a primary second molar without successor in the form of a permanent prilosec omeprazole dosing second premolar tooth in a patient. Hospital Episode Statistics (HES) data and procedural coding was used to identify all patients in England between April 2006 and March 2015 undergoing subtotal colectomy for UC. ARID1A-knockdown cells were treated with AKT inhibitor (GSK690693), 5-fluorouracil, or cisplatin, alone or in combination. Nine patients were included and all 20 other remaining patients reported in literature so far are discussed. CS-induced inflammatory responses and extent of emphysematous changes differ depending on the type of viral infection. In fact, the composition and properties of lipid bilayer play a pivotal role in the exposure of sugar residues and in the interaction with lectins. This study provides evidence in real world to support the performance of EVT in acute anterior circulation stroke patients in Chinese population.

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Use of titanium mesh for reconstruction of extensive defects in fronto-orbito-ethmoidal fracture. Paired pathways consisting of IL-8 and EIF2 signaling pathways with higher AUC of 0.975, were involved in 7 runs. Summary estimates of CBR (SCBR) and Odd Ratio for death (SOR) were calculated according with type of drug, ER and PgR status, platinum resistance, line of therapy, tumor grade and tamoxifen dose. Extension of right renal vein in renal transplant from deceased donors: cohort study. In the current study, we administered a cafeteria diet consisting of bacon, potato chips, cheesecake, cookies, breakfast cereals, marshmallows, and chocolate candies to male Wistar rats for 3-4 weeks, producing an obese phenotype. Expression of Flk-1 and Cyclin D2 mRNA in the Myocardium of Rats with Doxorubicin-Induced Cardiomyopathy and after Treatment with Betulonic Acid Amide. Effects of chronic antidepressant drug administration and electroconvulsive shock on activity of dopaminergic neurons in the ventral tegmentum. Timing of exposure and analysis of individual NSAIDs should be considered.

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To explore weight loss and metabolic effects of bariatric surgery on young people. Similar findings may be present in pulmonary hypertension (PH) associated with microscopic tumor embolism, which are thought to be related to the phenomenon of pulmonary tumor thrombotic microangiopathy (PTTM). Recently, a rigid bronchoscope has been used for stent placement without the need for fluoroscopy. Eight recreational female participants performed dominant and non-dominant single-leg drop landings from 30 to 60cm. Pancreatic ductal adenocarcinoma (PDAC) is the third highest cause of cancer-related deaths in the US, and is projected to be second only to non-small cell lung cancer (NSCLC) by the 2020s. Neurons exhibit asymmetric morphologies throughout development - from migration to the elaboration of axons and dendrites - that are correctly oriented for the flow of information.

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The primary outcome measures were body mass index (BMI) (kg/m2) and body weight (kg). These results provide strong evidence that EOAH effectively inhibits depression-like behavioral responses, brain CRF and TH expression increases, and brain 5-HT expression decreases in mice challenged with stress. A Combined Adaptive Neural Network and Nonlinear Model Predictive Control for Multirate Networked Industrial Process Control. These results indicate a decrease in expression of hepatic CYPs and their regulator GR in rats exposed to IH. Melanoma is the most serious skin cancer, and consistent use of sun protection is recommended to reduce risk. Alternatively, the degree of bone fusion in this primitive bird may have been related to modifications in genes or developmental paths. Prospective Evaluation of Patient Usage of Above and Below Threshold Waveforms With Traditional Spinal Cord Stimulation Devices. Lamivudine therapy for chronic hepatitis B virus infection and pregnancy: a case report. participants in the case group showed significant and differentiated improvement post-intervention when compared to the control group, which remained stable.

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Each clinician recruited 100 consecutive patients from outpatient clinics and reported their drug prescriptions, co-morbidities, and blood pressure (BP) levels. The histological types were non-small cell carcinoma lung cancer in four cases and metastatic carcinoma from renal cell carcinoma in one. Although prostaglandin E2 (PGE2) is known to stimulate bone formation in vivo, its mechanism of action is not well understood. Great strides have been made in developing biomarkers to guide therapy for women diagnosed with breast cancer. We conducted a longitudinal study including 737 participants who had muscular fitness measures in 1985 when age 9, 12, or 15 yr and attended follow-up in young adulthood 20 yr later when measures of MetS were collected. Small changes in peptide structure can alter or inhibit this response. Moreover, high levels of neck disability correlated with high levels of jaw disability.

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The ubiquitin ligase TRIM25 inhibits hepatocellular carcinoma progression by targeting metastasis associated 1 protein. Cryotherapy has been shown to be effective in the treatment of primary malignancies of the endobronchial tree. This neurological symptom of radiation damage to the brain developed within 75 days of hatching. There is significant evidence to support the role of selective serotonin reuptake inhibitors (SSRIs), novel agents, and classic agents in the treatment of major depressive disorder (MDD). We observed that significantly differentially expressed genes were sharply up- or down-regulated in the acute phase of MI, and then changed slowly until the chronic phase. Of those 4 patients, 2 have continued in remission after discontinuation of trastuzumab for more than 1 year. DR was graded according to International Clinical Diabetic Retinopathy Severity Scale and CSME was defined according to Early Treatment Diabetic Retinopathy Study (ETDRS) system. There is growing awareness that user-generated social media content contains valuable health-related information and is more convenient to collect than typical health data. Simulations have been employed to verify system feasibility, and a complete hardware implementation of the acoustic goniometer has been designed and field tested. In addition, congeners with improved physicochemical properties were identified which proved efficacious in murine sepsis and hamster C.

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In this model, the effects of sirolimus on influenza infection included severe weight imdur 30 pill loss and modified viral replication, respiratory function and lung inflammation. Axonal degeneration was prevented by preincubation of neurons with a caspase-6 inhibitor or siRNA of caspase-6. Tea tree oil (TTO) is a volatile essential oil obtained from the leaves of the Australian tree Melaleuca alternifolia by vapor distillation. All 5 patients were adult females, with an average age of 57.3 years. Effects of Granulocyte Colony-Stimulating Factor on Patients with Liver Failure: a Meta-Analysis. Torrefaction of corncob to produce charcoal under nitrogen and carbon dioxide atmospheres. CsPTX1, a pentraxin of Cynoglossus semilaevis, is an innate immunity factor with antibacterial effects.

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The NICHD gestational age estimation formula is associated with smaller errors than a well-established historical formula. By using green fluorescent protein reporters we demonstrate that gsr-1 produces two GSR-1 isoforms, one located in the cytoplasm and one in the mitochondria. We show that abscisic acid (ABA), an antagonist of GA, is also transported by NPF3 in vitro. Bisphenol A (BPA), used in the manufacture of plastics, is ubiquitously distributed in the aquatic environment. There are only a few methods that allow one to measure supercoiling in chromosomal DNA and analyze the role of gyrase in albendazole dosage forms transcription and its interaction with the other three bacterial topoisomerases.

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High functional efficiency of redox enzymes is a direct consequence of nonergodicity. Virulence factors and antibiotic resistance of Helicobacter pylori isolated from raw milk and unpasteurized dairy products in Iran. Plasma substance P concentrations at 24 and 72 hours after chemotherapy were measured. Protease inhibitor-sparing regimens, including nevirapine, seem to be an effective alternative for PI-experienced patients. This study aimed to proof the usefulness of immunohistochemical staining for calretinin in rule out of Hirschsprung disease.

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