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Angibloc (Losartan)
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Angibloc

Angibloc belongs to a group of medicines known as angiotensin-II receptor antagonists. Angiotensin-II is a substance produced in the body which binds to receptors in blood vessels, causing them to tighten. This results in an increase in blood pressure. Angibloc prevents the binding of angiotensin-II to these receptors, causing the blood vessels to relax which in turn lowers the blood pressure. Angibloc slows the decrease of kidney function in patients with high blood pressure and type 2 diabetes.

Other names for this medication:
Angibloc, Angioten, Anreb, Arapres, Aratan, Biortan, Cormac, Covance, Eklips, Enromic, Fensartan, Giovax, Hilos, Hizaar, Insaar, Lifezar, Loben, Loctenk, Logika, Lortaan, Losadel, Losadrac, Losan, Losaprex, Losar, Losargamma, Losart, Losartan, Losartanum, Losatan, Losazide, Lospre, Lotar, Lotim, Lozap, Lozatan, Ocsaar, Omnitan, Ozarium, Prelow, Prosan, Sartens, Sarvas, Sedeten, Simperten, Sortal, Tensaar, Tiasar, Zartan

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Also known as: Losartan

Description

Angibloc is indicated for the treatment of hypertension in adults and pediatric patients 6 years of age and older, to lower blood pressure. Lowering blood pressure lowers the risk of fatal and nonfatal cardiovascular (CV) events, primarily strokes and myocardial infarction. These benefits have been seen in controlled trials of antihypertensive drugs from a wide variety of pharmacologic classes including losartan.

Control of high blood pressure should be part of comprehensive cardiovascular risk management, including, as appropriate, lipid control, diabetes management, antithrombotic therapy, smoking cessation, exercise, and limited sodium intake. Many patients will require more than 1 drug to achieve blood pressure goals. For specific advice on goals and management

Angibloc is indicated to reduce the risk of stroke in patients with hypertension and left ventricular hypertrophy, but there is evidence that this benefit does not apply to Black patients

Angibloc is indicated for the treatment of diabetic nephropathy with an elevated serum creatinine and proteinuria in patients with type 2 diabetes and a history of hypertension. In this population, Angibloc reduces the rate of progression of nephropathy as measured by the occurrence of doubling of serum creatinine or end stage renal disease

Dosage

Take Angibloc tablets orally with or without food. Do not crush or chew it. Take Angibloc once or twice a day at the same time. If you want to achieve most effective results do not stop taking Angibloc suddenly.

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children in a container that small children cannot open.

Side effects

The most common side effects associated with Angibloc are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Use of drugs that act on the renin-angiotensin system during the second and third trimesters of pregnancy reduces fetal renal function and increases fetal and neonatal morbidity and death. Resulting oligohydramnios can be associated with fetal lung hypoplasia and skeletal deformations. Potential neonatal adverse effects include skull hypoplasia, anuria, hypotension, renal failure, and death. When pregnancy is detected, discontinue Angibloc as soon as possible.

In patients with an activated renin-angiotensin system, such as volume- or salt-depleted patients (e.g., those being treated with high doses of diuretics), symptomatic hypotension may occur after initiation of treatment with Angibloc. Correct volume or salt depletion prior to administration of Angibloc.

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