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Alprazolam is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder. It's also used in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Alprazolam, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Alprazolam is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Alamflu, Alflux, Alprogard, Alpron, Alproz, Alsert, Altalin, Alzin, Alzokam, Anxit, Copax, Dexolam, Dizeral, Ecsit, Endolam, Exiten, Fledore, Indolam, Kaprolam, Niravam, Onapract, Orten, Parazolam, Procalm, Pronext, Rescalm, Samrox, Unixl, Wycalm, Zolipax

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Alprazolam XR (alprazolam) is in a group of drugs called benzodiazepines (ben-zoe-dye-AZE-eh-peens). Alprazolam affects chemicals in the brain that may become unbalanced and cause anxiety.

Alprazolam XR is used to treat anxiety disorders, panic disorders, and anxiety caused by depression.

Alprazolam XR may also be used for other purposes not listed in this medication guide.


Take Alprazolam XR exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

Your doctor may occasionally change your dose to make sure you get the best results from this medication.

Alprazolam XR may be habit-forming and should be used only by the person it was prescribed for. Alprazolam XR should never be shared with another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it. Do not crush, chew, or break a Alprazolam extended-release tablet. Swallow the tablet whole. It is specially made to release alprazolam slowly in the body. Breaking the tablet would cause too much alprazolam to be released at one time.

Contact your doctor if this medicine seems to stop working as well in treating your panic or anxiety symptoms.

Your symptoms may return when you stop using Alprazolam XR after using it over a long period of time. You may also have seizures or withdrawal symptoms when you stop using Alprazolam XR.

Withdrawal symptoms may include blurred vision, trouble concentrating, loss of appetite, diarrhea, muscle twitching, numbness or tingling, or increased sensations.

Do not stop using Alprazolam XR suddenly without first talking to your doctor. You may need to use less and less before you stop the medication completely.

To be sure this medication is helping your condition, your doctor will need to check your progress on a regular basis. Do not miss any scheduled visits to your doctor.

Store Alprazolam XR at room temperature away from moisture, heat, and light. Remove any cotton from the bottle of disintegrating tablets, and keep the bottle tightly closed.

Keep track of how many pills have been used from each new bottle of this medicine. Benzodiazepines are drugs of abuse and you should be aware if any person in the household is using this medicine improperly or without a prescription.

Detailed Alprazolam XR dosage information


If you have been prescribed Alprazolam for medical reasons, the best way to avoid a Alprazolam overdose is to adhere to prescribed orders—closely monitor your dose and the time at which you take your medication. Track your Alprazolam consumption in a notebook or on your phone. If you notice that you are taking a higher dose of the drug, taking the drug more often, or you want to consume more of the drug, talk with your doctor immediately.


Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details.

Side effects

The most common side effects associated with Alprazolam are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not drink alcohol while taking Alprazolam XR. This medication can increase the effects of alcohol. Alprazolam XR can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Grapefruit and grapefruit juice may interact with Alprazolam XR and lead to potentially dangerous effects. Discuss the use of grapefruit products with your doctor. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor.

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The purpose of this study was to investigate whether blood mercury concentrations associated with the presence of dry eye symptoms in a nationally representative Korean population. Better predictive understanding will emerge in the coming years from analyses regarding how these variables interact with each other. A Comparison of 4 Emergency Tapes With Different Length-Based Weight Categorization. Perioperative variables and bone tamp complications or issues were recorded and analyzed. Our data indicate the involvement of abnormal bone turnover, necessity of whole-body scanning, and association of higher serum IgG levels and greater numbers of inflammatory lesions with prolonged disease activity in patients with CNO. This review focuses on identifying critical research-practice gaps, addressing real-world challenges and pinpointing real-time insights in general terms under the context of clinical cardiotoxicity induced by the fourth and fifth modalities of cancer treatment. The pial artery in the contralateral hemisphere (C.H) of the severe MCAO group reacted more slowly than both hemispheres in the normal and mild MCAO groups. Understanding host-microbiota interactions on a cellular level may facilitate signaling pathways that contribute to health and disease and thus provide new therapeutic strategies. Pioneer Axon Navigation Is Controlled by AEX-3, a Guanine Nucleotide Exchange Factor for RAB-3 in Caenorhabditis elegans.

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This study compares periodontal treatment results in healthy patients and patients with breast cancer undergoing chemotherapy by monitoring clinical conditions and C-reactive-protein (CRP) levels. Change deafness, the inability to notice changes to auditory scenes, has the potential to provide insights about sound perception in busy situations typical of everyday life. The chronic toxoplasmosis, primarily regarded as benign and asymptomatic, might be responsible, in light of current scientific evidence, for a vast array of neuropsychiatric symptoms. Sarcomas typically lack the classic kinase alterations seen in many carcinomas. We reviewed recent studies of stroke associated with varicella and zoster, how VZV vasculopathy is verified virologically, vaccination to prevent varicella and immunization to prevent zoster, and VZV in giant cell arteritis (GCA). A non-canonical E-box sequence housing a putative c-Myc binding site was detected on the FKBP4 promoter using in silico search. Furthermore, Bmal1 is involved in TP-stimulated Nrf2/ARE/HO-1 and AKT/CREB/BDNF signaling pathway. Fluorescent labeling of cardiac progenitor cell mitochondria revealed that hyperglycemia alters mitochondrial dynamics and increases expression of fission-related proteins, including Fis1 and Drp1. Modelling and monitoring organochlorine and heavy metal accumulation in soils, earthworms, and shrews in Rhine-delta floodplains. Here we develop a new technique to establish such transformations for mapping data that cannot be achieved by existing approaches and that can be used interactively for expert editorial review.

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To evaluate the effect of human chorionic gonadotrophin (hCG) on pregnant human myometrial contractility in vitro and to determine whether the hCG-elicited effect was oestrogen dependant. Enhancement of Agkistrodon piscivorus piscivorus venom phospholipase A2 activity toward phosphatidylcholine vesicles by lysolecithin and palmitic acid: studies with fluorescent probes of membrane structure. The authors observed psychosensory disturbances not typical, according to the literature for attacks of ataxia, dysarthria and nystagmus. Its non-conserved regions, which are located between the conserved domains and at the C-terminus, contain sites for phosphorylation by multiple protein kinases. Embodied Valuation: Directional Action is Associated with Item Values. Furthermore, we characterized the expression of SMA-mCherry in relation to endogenous SMA in the embryo and in adult tissues, and found that the transgenic reporter in each line recapitulated endogenous SMA expression at all time points. By using laterally asymmetric triangular-shaped microstructures, it is demonstrated that interfacial DMI combined with an in-plane magnetic field yields a unique and significant shift in magnetic hysteresis.

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MCP inhibition could provide a safer alternative to conventional antifibrotic adjunctive treatments in GFS. Furthermore, the prognosis for gonadoblastoma accompanied by germ cell tumors other than dysgerminoma was very poor in the past, but the patient remains well 25 months after the first operation. Nicotine, as an aromatase inhibitor, inhibits estrogen synthesis and may allow for greater production of gonadotropins. We observed considerable heterogeneity in sensitivity of HNSCC cell lines to CCI-779 monotherapy. Devices to Perform Laparo-Endoscopic Single Site Surgery for Urachal Remnants without Additional Ports. Rabies virus variants circulating in different host populations can be distinguished by the use of monoclonal antibodies and by genomic analysis.

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This condition can permanently damage these structures and can cause implant instability. Hydralazine-induced pauci-immune glomerulonephritis: intriguing case series with misleading diagnoses. The EVS tool was successfully implemented in large, integrated practices utilizing electronic health record systems. Malaria is an important cause of morbidity and mortality in malaria endemic countries. Of particular popularity, more recently, is the percutaneous intramedullary techniques for fixation flagyl oral dosage of these injuries. These data indicate that in addition to the m3-receptor subtype present in the trabecular meshwork this tissue also features the m2 receptor. An anonymous 13-question survey was formulated using a pilot survey sent to members of the plastic surgery department at the University of Florida.

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Herein, we discuss a wide range of medical, biomedical and scientific literature that includes reports from the fields of dentistry, general medicine, obstetrics and gynecology, pharmacology and toxicology to provide an update on the use (including indications, contraindications and concerns) of major classes of analgesics during human pregnancy. Development and Evaluation of a Radiation Safety Program in the NICU. Serum AFP levels may provide useful information for monitoring the therapeutic effectiveness, early recurrence or metastases. The immunopathological spectrum of crescentic glomerulonephritis: a survey of 106 patients in a single Chinese center. The majority of obese children have no underlying medical disorder causing their obesity yet a significant proportion might suffer from obesity-related co-morbidities. Urinary tract infections (UTIs) are a significant cause of morbidity among older adults. Geometric complexity identifies platelet activation in familial hypercholesterolemic patients. Clinical severity was assessed as mild, moderate, or severe in 35 of the patients. In contrast, phenylephrine showed vasoconstriction in the systemic, renal, and uterine circulations in both pregnant and nonpregnant sheep.

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