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Alpranex (Alprazolam)

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Alpranex is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder. It's also used in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Alpranex, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Alpranex is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Alprasan, Alzocum, Alzokam, Alzolam, Alzolite, Alzotime, Anilam, Anlzium, Anxicalm, Ateez, Axnil, Azoslip, Coolam, Depser, Depsolam, Hipose, Kaprolam, Maxorest, Mcalm, Omelam, Optizole, Paxor, Poize, Proprazolam, Prozam, Restam, Resto, Rivcam, Sertakem, Silam, Somnirest, Tenfree, Tenil, Tenschem, Tensyl, Trapose, Trustin, Xylonite, Zeprax, Zocam, Zolin

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Also known as: Alprazolam


Alprazolam is used to relieve symptoms of anxiety, including anxiety caused by depression. It is also used to treat panic disorder in some patients.

Alprazolam is a benzodiazepine. Benzodiazepines belong to the group of medicines called central nervous system (CNS) depressants, which are medicines that slow down the nervous system.

This medicine is available only with your doctor's prescription.


Take Alpranex XR exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

Your doctor may occasionally change your dose to make sure you get the best results from this medication.

Alpranex XR may be habit-forming and should be used only by the person it was prescribed for. Alpranex XR should never be shared with another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it. Do not crush, chew, or break a Alpranex extended-release tablet. Swallow the tablet whole. It is specially made to release alprazolam slowly in the body. Breaking the tablet would cause too much alprazolam to be released at one time.

Contact your doctor if this medicine seems to stop working as well in treating your panic or anxiety symptoms.

Your symptoms may return when you stop using Alpranex XR after using it over a long period of time. You may also have seizures or withdrawal symptoms when you stop using Alpranex XR.

Withdrawal symptoms may include blurred vision, trouble concentrating, loss of appetite, diarrhea, muscle twitching, numbness or tingling, or increased sensations.

Do not stop using Alpranex XR suddenly without first talking to your doctor. You may need to use less and less before you stop the medication completely.

To be sure this medication is helping your condition, your doctor will need to check your progress on a regular basis. Do not miss any scheduled visits to your doctor.

Store Alpranex XR at room temperature away from moisture, heat, and light. Remove any cotton from the bottle of disintegrating tablets, and keep the bottle tightly closed.

Keep track of how many pills have been used from each new bottle of this medicine. Benzodiazepines are drugs of abuse and you should be aware if any person in the household is using this medicine improperly or without a prescription.

Detailed Alpranex XR dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of alprazolam can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, and fainting.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Alpranex XR dosage information

Side effects

The most common side effects associated with Alpranex are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies have not been performed on the relationship of age to the effects of alprazolam in the pediatric population. Safety and efficacy have not been established.

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