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Alpra (Alprazolam)

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Alpra is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder. It's also used in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Alpra, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Alpra is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Acalm, Alflux, Allam, Alpraquil, Alprine, Alprocontin, Alprowon, Alzorix, Ambulax, Anlzium, Ansilumirm, Anxico, Azoslip, Fludep, Morecalm, Norex, Oclam, Prolam, Proprazolam, Prosanti, Restam, Richpram, Trustin, Xanti, Zeecam, Zenax, Zoldac, Zoloid, Zolyde

Similar Products:
Chloromycetin, Benemid, Adalat, Albenza, Xanax, Vasotec, Avana, Abilify, Cefdolife, Mycort, Balzam, Oributol, Amlocas, Aviband, Amdinx,

Also known as: Alprazolam


Alpra (alprazolam) is a benzodiazepine (ben-zoe-dye-AZE-eh-peen). It is thought that alprazolam works by enhancing the activity of certain neurotransmitters in the brain.

Alpra is used to treat anxiety disorders and anxiety caused by depression.

Alpra is also used to treat panic disorders with or without a fear of places and situations that might cause panic, helplessness, or embarrassment (agoraphobia).

It is dangerous to purchase Alpra on the Internet or outside the United States. The sale and distribution of medicines outside the U.S. does not comply with safe-use regulations of the Food and Drug Administration (FDA). These medications may contain dangerous ingredients, or may not be distributed by a licensed pharmacy.


Usual Adult Dose for Anxiety:

Immediate-release tablets: 0.25 to 0.5 mg orally administered 3 times a day -Maximum dose: 4 mg/day

Usual Adult Dose for Panic Disorder:

Immediate-release tablets: 0.5 mg orally administered 3 times a day -Maximum dose: 10 mg/day Extended-release tablets: -Initial dose: 0.5 to 1 mg orally once a day -Maintenance dose: 3 to 6 mg orally per day, preferably in the morning -Maximum dose: 10 mg/day Comments: -The lowest possible effective dose should be administered and the need for continued treatment reassessed frequently. -Dosage should be reduced gradually when discontinuing therapy or when decreasing the daily dosage. -The daily dosage may be decreased by no more than 0.5 mg every 3 days; however, some patients may require an even slower dosage reduction. -The dose of extended-release tablets may be increased at intervals of 3 to 4 days in increments of no more than 1 mg per day. -The times of administration should be distributed as evenly as possible throughout the waking hours.

Usual Geriatric Dose for Anxiety:

Elderly or debilitated patients: Immediate-release tablets: 0.25 mg orally administered 2 or 3 times a day.

Usual Geriatric Dose for Panic Disorder:

Elderly or debilitated patients: Immediate-release tablets: -Initial dose: 0.25 mg orally administered 2 or 3 times a day Extended-release tablets: -Initial dose: 0.5 mg orally once a day Comments: -If side effects develop, the dose may be lowered. -The lowest possible effective dose should be administered and the need for continued treatment reassessed frequently. -Dosage should be reduced gradually when discontinuing therapy or when decreasing the daily dosage.

Detailed Alpra dosage information


Seek emergency medical attention if you think you have used too much of this medicine. An overdose of Alpra XR can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, fainting, and coma.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Alpra dosage information

Side effects

The most common side effects associated with Alpra are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies have not been performed on the relationship of age to the effects of alprazolam in the pediatric population. Safety and efficacy have not been established.

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The purpose of this study was to record qualitative and quantitative histopathological artifacts and to assess differences between artifacts found in specimens obtained by different surgical polypectomy techniques. In this study we report a longer-lived mouse model that also develops osteosclerosis and a genetic manipulation that completely rescues the phenotype. The following preparations were studied: 1) preparation obtained by means of the cell culture cryoconcentration, 2) ethanol extract of the cell culture, 3) high-molecular protein containing fraction of the bioginseng I. Recently, several duplicated TAF proteins have been identified in higher eukaryotes, but their functional diversity has been so far poorly characterized. The readability of information and consent forms in clinical research in France. The phylogeographic analyses indicated that one group (associated with West African populations) was found in all the cities throughout the sampling while the second group (associated with East African populations) was found in all the samples from Bello and in only one sampling from Riohacha. Distinct features of intraspecific and intrapopulation variability of the skull size in the red fox.

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Except for a very small age effect, none of the potential risk factors had significant effects on global tolerability. Serum HEV RNA became negative by Week 3 of Peg-IFN-alpha-2a therapy, and remained negative until the last follow-up, i.e. Unlike in premolar extraction cases, space closure in mandibular incisor extraction cases is unique in which the extraction space will be in the middle of the arch. Descriptive statistics characterized learning settings and the status of PCMH features, and generalized linear mixed models examined variation among medical schools (as the 104 clinics were nested within nine medical schools). More than 1.5 billion people worldwide suffer from chronic pain, yet current treatment strategies often lack efficacy or have deleterious side effects in patients. In the case of infrared and noisy images, simple naive fusion leads to unsatisfactory results due to the discrepancies in brightness and image structures between the image pair. These data suggest that Gal-3 could be a potential therapeutic candidate for the prevention of early renal alterations in hypertension. Factors which appeared significantly more frequently in the injured group were included further into multiple logistic regression analysis. The impact of nursing grade on the quality and outcome of nursing care.

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A total of 1664 patients with Stage T1-T2N0M0 with a unilateral renal mass underwent nephrectomy. Our data demonstrate for the first time the involvement of Eps8 in the morphological processes required for in vitro angiogenesis, and suggest that this protein might represent a common target for the design of new anticancer drugs, acting at the same time on both tumor and endothelial cells. Hence, we determined the clinical value of PORT in IMPC patients. The genetic distances among the 13 Latin American populations in this analysis show contributions from both differences in ancestry and differences in genetic drift. To review the evidence concerning the use of HBOT as an adjunctive treatment for patients with necrotizing fasciitis (NF). Terahertz radiation using log-spiral-based low-temperature-grown InGaAs photoconductive antenna pumped by mode-locked Yb-doped fiber laser. The resulting databases of energy-ranked feasible conformations of the luciferase complexes with flavin mononucleotide, omega-phosphopentylflavin, omega-phosphobutylflavin, and omega-phosphopropylflavin were filtered according to the structure-activity profile of these analogs. The profile of peptidic fractions released was studied by RP-HPLC.

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The survey comprised questions measuring: health literacy, health status, medication safety (measured by reported MRPs), missed dose(s), role of health professionals, health services and cost, and socio-demographic status. These data show that the Ah receptor itself and two forms of the Arnt protein are the major components of the purified DNA-binding form of receptor. In this species, host specialization may facilitate increased population growth and allow more opportunities for selection to act. A combined assessment using spirometry and quantitative computed tomography helped to characterize the respiratory dynamics underlying the volume reduction effect, thus leading to the identification of novel predictors of a volume reduction effect after lobectomy for cancer. Only the growth of the MDA-MB-231 cells was significantly reduced after a longer exposure time to nitrous oxide, but those of the other cells were not. Effects of magnesium sulfate on hemodynamic response to carbon dioxide pneumoperitoneum in patients undergoing laparoscopic cholecystectomy.

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Changes in Periodontal Parameters and C-Reactive Protein After Pregnancy. Distal interphalangeal (DIP) arthroplasty has been successful in preserving motion and alleviating pain for distal DIP, proximal interphalangeal, and metacarpophalangeal joints. S-1 and S-2-alar-iliac screw fixation via intraoperative navigation. For quantitatively accurate X-ray intensity measurements, the XFC should be used with limited incident photon flux such that the gain linearity is guaranteed. The increase in AIDS mortality observed in the three European cities in the mid-80s and mid-90s has yielded substantial changes in the pattern of the main causes of death at young ages in Barcelona and Bologna. This may be due to age-related dopamine (DA) decline affecting neural processing in striatum, prefrontal cortex, or both.

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Despite rapid progress in this area, the temporal dynamics governing the functional connectivities that underlie RSN structure remain poorly understood. Extracellular matrix modulates expression of connexin messenger RNA and protein by alveolar epithelial cells. Endocan concentrations in postmortem serum, vitreous humor and urine in victims of lethal hypothermia. In this article, we briefly review different pathways of death signaling and alterations in apoptotic signaling pathways in order to understand changes in various T cells in human aging. In fruits with therapeutic properties for antidiarrheal and laxative uses, the presence of lectins may be the bioactive properties that interfere with bacterial adhesion, thought to be competition for glycoside signal sites in the attachment. Modified virus Ankara (MVA)-BN, a highly attenuated strain of vaccinia virus, was developed for vaccination with improved safety profile.

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Individuals who used controlled substances other than alcohol or cannabis were more likely to have a positive toxicology result than those who used alcohol or cannabis only or those with no alcohol/drug history. Twenty-five patients (10 women, 15 men) with subtemporal fossa tumours were included in the study. Solvatomorphs II, IV, and V, along with their single-crystal structures, were reported for the first time. Avoiding acyclovir neurotoxicity in patients with chronic renal failure undergoing haemodialysis. In ubiquitin, evidence for slow motion is found in loops or near the ends of beta-strands and alpha-helices. Genetic Profiles of Different Subsets of Merkel Cell Carcinoma Show Links between Combined and Pure MCPyV-negative Tumors. Fourier polarimetry of human skin in the tasks of differentiation of benign and malignant formations. We present a case of invasive thymoma with intravascular invasion of the superior vena cava extending into the right atrium. In the ten-year base-case analysis, bariatric surgery led to a cost increment of 19,332 DKK and generated an additional 1.1 quality-adjusted life years (QALYs).

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By means of density functional theory computations, we examine the stability and CO oxidation activity of single Ru on CeO2 (111), TiO2 (110) and Al2 O3 (001) surfaces. Progesterone (100 mg/d) was added when oocytes became available. Purified RAD51C--XRCC3 complex binds single-stranded, but not duplex DNA, to form protein--DNA networks that have been visualized by electron microscopy. Individuals whom have a significant decrease in QOL or have frequent or severe attacks and who fail or are intolerant to androgens should be considered for long-term prophylaxis with C1INH. However, the relationship between the work schedule and the degree of impairment remains unclear. At the same time, water samples for particulate and dissolved metals were taken every 3 days for the duration of the experiment. By this procedure a list of reasons for failure of action, i.e., for disability and handicap, is obtained. Our method allows perceptually motivated level of detail methods for real-time rendering applications by detecting configurations with expected visual masking.

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To refine the existing language protocol, we tested two different repetition rates of 5 Hz/10 pulses and 7 Hz/10 pulses with a 0 ms delay in 19 healthy subjects. EM residents may benefit from educational interventions to increase exposure to these topics. HLFA importance was supported by study of recombinant inbred lines (JI64xJI92) contrasting in dormancy but similar in other seed properties. Surgeon preference has often dictated those changes with regard to incisional approaches, fixation methods, and use of bone graft and biologics but one constant has always remained: open ankle arthrodesis is a predictable, time-tested procedure with consistent results when performed in appropriate patients. We analyzed 24-locus Mycobacterial Interspersed Repetitive Units-Variable Number of Tandem Repeats (MIRU-VNTR) genotyping for 2,290 Mycobacterium tuberculosis (Mtb) clinical isolates collected in the province of British Columbia, Canada (2005-2014).

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Oncogenic EGFR Represses the TET1 DNA Demethylase to Induce Silencing of Tumor Suppressors in Cancer Cells. Associations between sex-typed behaviour at age 31/2 and levels and patterns of physical activity at age 12: the Avon Longitudinal Study of Parents and Children. Estimating thumb-index finger precision grip and manipulation potential in extant and fossil primates. To determine whether this editing system induced mutations in the medaka genome at the one-cell stage, recombinant Cas9 protein, tracrRNA and crRNA for dead end (dnd), which is essential for germ cell development, were injected into one-cell stage embryos of olvas-DsRedExpress transgenic medaka. Insights into Wnt binding and signalling from the structures of two Frizzled cysteine-rich domains. Increased monocyte-to-HDL cholesterol ratio is related to cardiac syndrome X. However, we found three putative Multidrug And Toxic Compound Extrusion (MATE) transporter genes within this QTL and one adjacent to it (GmMATE1-4).

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The aims of this study were to determine the incidence and outcomes of patients presenting to asacol 400 mg tablet a tertiary hospital ED with ALGIH and to identify associated clinicopathological risk factors. To explore the impact on survival and long-term prognosis of central pulmonary embolism. Women with SBBC can be safely treated with HT and this is not associated with adverse short- to intermediate term radiation toxicity. We have shown that, at the activity level, the colocation of AS was changing during fetal and neonatal development and was under the control of corticosteroid and pancreatic hormones. ICRP Publication 135: Diagnostic Reference Levels in Medical Imaging.

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Stiffness of biomaterial substrates plays a critical role in regulation of cell behavior. The Sternal Talon (KLS Martin Group, Jacksonville, FL), a lightweight titanium closure device is designed to encircle the sternum, thus yielding a stable closure by effectively distributing the strength of closure over the entire length of the sternotomy. Changes in bone and calcium metabolism following hip fracture in elderly patients. The patients were categorized according to their SV pathologies. CD44 was expressed in the membrane of serous and mucous acini as well as in the ductal cells in normal gland tissue. We hypothesize that this phenomenon of isolated relapse in a sanctuary site could be due to the altered biology and pattern of metastasis as a result of effective adjuvant systemic chemotherapy.

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Inhibition in motor imagery: a novel action mode switching paradigm. Beyond Psychometrics: The Difference between Difficult Problem Solving and Complex Problem Solving. YBMSM who are high in both internalized and enacted heterosexism may see greater benefits from social support on condom self-efficacy than would YBMSM who grapple with less heterosexism. The use of moulage technique to develop dermatologic lesions on simulated patients may be utilized for student assessment. Patients with tumors containing elevated cytoplasmic Ape1 had a poor prognosis and a 3.722-fold risk of tumor recurrence and/or metastasis.

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Treatment trials or prospective descriptions of outcome for actinomycetoma should investigate treatment efficacy for the different members of Actinomycetales, particularly Nocardia spp., with short-term and long-term treatment courses. While treatment failure would be surprising in neutrophilic dermatoses, the picture might be more complex in lymphocyte-mediated conditions. The results showed that exposure doses from drinking water pathways were very low. Retinol showed no significant effect on cell proliferation or elastin synthesis. Nuclear envelopathies: a complex LINC between nuclear envelope and pathology. The primary outcomes will be changes in dietary habits, knowledge tenormin ls 50 mg tablets and physical activity of children and adults.

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Beyond radiological imaging tenormin dosage form : Direct observation and manual physical evaluation of spinal instability. As the molecular weight decreased, film thickness and porosity decreased, while m-cresol permeability increased. To our knowledge, this is the first report of the efficacy of interferon in congenital dyserythropoiesis. Rotavirus specifically infects the small intestine of young infants resulting in severe diarrhoea. Although no additional treatment was performed, the patient has been free of systemic symptoms and recurrences. X-ray and cryo-EM structures of tetrameric and pseudo-tetrameric P-loop channels are used to elaborate homology models of mammalian voltage-gated sodium channels with drugs and neurotoxins. The application of these diffusion models and pathways is of vital importance for future studies of developmental processes, disease modeling, and tissue regeneration.

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Identifying trace metal distribution and occurrence loading dose of dilantin in adult in sediments, inundated soils, and non-flooded soils of a reservoir catchment using Self-Organizing Maps, an artificial neural network method. The role of tumor necrosis factor in acute pancreatitis and associated multiple organ failure. A new framework is being created that will allow new additions to the NSAID class of medications. The gold standard method for the diagnosis of VCD is fiberoptic laryngoscopy, which may also identify concomitant laryngeal abnormalities other than VCD. Fermions and bosons are fundamental realizations of exchange statistics, which governs the probability for two particles being close to each other spatially. Fundamental issues for using databases for research are the completeness of capture of cases within the population and time period of interest and accuracy of the diagnosis of diabetes and outcomes of interest. Glucocorticoids transcriptionally regulate the expression of miR-19b via a glucocorticoid receptor-mediated direct DNA binding mechanism. This enzyme produces ?-glutamylhydroxamate in the presence of l-glutamic acid and hydroxylamine as substrates.

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The basic helix I sequence of the bHLH motif contains a consensus sequence for protein kinase C (PKC) substrates. The boy became somewhat hyperactive and irritable after the second dose. A search engine that discovers more peptides reliably is essential to the progress of the computational proteomics. We find that conformational rigidity in the backbone is an important feature for eliciting this feature. Eighty-seven full-thickness excisional skin wounds were created on the back of 6 pigs and then transplanted with either cultured or noncultured autologous keratinocytes. As he would limp occasionally during the treatment, he had an orthopedic examination at our hospital, and shrinkage of the right femoral head was disclosed.

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Ninety-four patients with completely resected pathologic stage I lung adenocarcinoma were retrospectively reviewed. This study investigated patient demographics of a former dental franchise in Chicopee, Massachusetts, and examined a correlation between dental insurance and edentulism in this group. The proposed approach and MC methods are compared by analysing the alcohol intake distribution in a sub-population of individuals at risk of developing metabolic syndrome. Change in HbA1c levels between the age of 8 years and the age of 12 years in Dutch children without diabetes: the PIAMA birth cohort study. To determine the association of body mass index (BMI) and visceral fat with AVC and mortality after transcatheter aortic valve replacement (TAVR). The appealing aspect of molecular biology tools relying on BL reactions is their general applicability in both in vitro assays, such as cell cultures or purified proteins, and in vivo settings, such as in whole-animal BL imaging.

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In conclusion, this work extended prior literature by showing specific CLBP-related alterations in multi-segment spinal kinematics during gait. The items were not well targeted to the persons, with skewness towards high energy. Interest in, knowledge of, and consideration of psychiatry as a career were also assessed. To examine whether spironolactone could reduce the severity of obstructive sleep apnea (OSA) and lower blood pressure in enalapril 20 mg para q sirve patients with resistant hypertension. In the first case, a high myoglobin clearance at admission (27 mL/min) was accompanied by normal serum creatinine and creatinine clearances.

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