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Alafex (Fexofenadine)

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Alafex is an effective medical drug for allergy caused by chemical histamine which is formed in our body naturally and reacts to the external irritants causing the allergic reaction. Alafex blocks the production and increased activity of histamine receptors as a result of which there is a reduction of the response reaction to the external irritants and the main symptoms of allergy are reduced. This drug helps to reduce cold, lacrimation, sneezing, itching, edema and other allergic symptoms.

Other names for this medication:
Alernex, Allefast, Allegix, Allermax, Altiva, Biofen, Coligra, Fegra, Fenax, Fenixa, Fenofex, Fexidine, Fexigra, Fexofast, Fexokast, Fexon, Fexona, Fexor, Fexotab, Fexotrol, Fextral, Infexo, Irmont, Maxgra, Nexofex, Novamont, Ofena, Oregra, Radifex, Rafen, Rexhist, Rhinofex, Xdine

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Also known as: Fexofenadine


Cough/cold combinations are used mainly to relieve the cough due to colds, influenza, or hay fever. They are not to be used for the chronic cough that occurs with smoking, asthma, or emphysema or when there is an unusually large amount of mucus or phlegm (pronounced flem) with the cough.

Cough/cold combination products contain more than one ingredient. For example, some products may contain an antihistamine, a decongestant, and an analgesic, in addition to a medicine for coughing. If you are treating yourself, it is important to select a product that is best for your symptoms. Also, in general, it is best to buy a product that includes only those medicines you really need. If you have questions about which product to buy, check with your pharmacist.

Since different products contain ingredients that will have different precautions and side effects, it is important that you know the ingredients of the medicine you are taking. The different kinds of ingredients that may be found in cough/cold combinations include:

Antihistamines—Antihistamines are used to relieve or prevent the symptoms of hay fever and other types of allergy. They also help relieve some symptoms of the common cold, such as sneezing and runny nose. They work by preventing the effects of a substance called histamine, which is produced by the body. Some examples of antihistamines contained in these combinations are:

Bromodiphenhydramine Brompheniramine Carbinoxamine Chlorpheniramine Dexchlorpheniramine Diphenhydramine Doxylamine Phenindamine Pheniramine Phenyltoloxamine Pyrilamine Promethazine Triprolidine

Decongestants—Decongestants produce a narrowing of blood vessels. This leads to clearing of nasal congestion. However, this effect may also increase blood pressure in patients who have high blood pressure. These include:

Ephedrine Phenylephrine Pseudoephedrine

Antitussives—Antitussives help relieve coughing and are some contain a narcotic. These antitussives act directly on the cough center in the brain. Narcotics may become habit-forming, causing mental or physical dependence, if used for a long time. Physical dependence may lead to withdrawal side effects when you stop taking the medicine.

Narcotic antitussives Codeine Dihydrocodeine Hydrocodone Hydromorphone

Non-narcotic antitussives Carbetapentane Caramiphen Dextromethorphan

Expectorants—Expectorants work by loosening the mucus or phlegm in the lungs. The main expectorant used in cough and cold medicines is guaifenesin. Other ingredients added as expectorants (for example, ammonium chloride, calcium iodide, iodinated glycerol, ipecac, potassium guaiacolsulfonate, potassium iodide, and sodium citrate) have not been proven to be effective. In general, the best thing you can do to loosen mucus or phlegm is to drink plenty of water.

Analgesics—Analgesics are used in these combination medicines to help relieve the aches and pain that may occur with the common cold. These include:

Acetaminophen Aspirin Other salicylates such as salicylamide and sodium salicylate

The use of too much acetaminophen and salicylates at the same time may cause kidney damage or cancer of the kidney or urinary bladder. This may occur if large amounts of both medicines are taken together for a long time. However, taking the recommended amounts of combination medicines that contain both acetaminophen and a salicylate for short periods of time has not been shown to cause these unwanted effects.

Anticholinergics—Anticholinergics, such as homatropine may help produce a drying effect in the nose and chest.

These cough and cold combinations are available both over-the-counter (OTC) and with your doctor's prescription.

Do not give any over-the-counter (OTC) cough and cold medicine to a baby or child under 4 years of age. Using these medicines in very young children might cause serious or possibly life-threatening side effects .


This section provides information on the proper use of a number of products that contain fexofenadine and pseudoephedrine. It may not be specific to Alafex-D. Please read with care.

Swallow the extended-release tablet whole. Do not crush, break, or chew it before swallowing.

This medicine is best taken on an empty stomach (either one hour before or two hours after a meal).

This medicine should be taken with water. Do not take with fruit juices or antacids.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage form (extended-release tablets [12 hour]): For symptoms of hay fever: Adults and teenagers—1 tablet two times a day. Children 4 years of age and older—Use and dose must be determined by your doctor. Children and infants up to 4 years of age—Use is not recommended . For oral dosage form (extended-release tablets [24 hour]): For symptoms of hay fever: Adults and teenagers—1 tablet one time a day. Children 4 years of age and older—Use and dose must be determined by your doctor. Children and infants up to 4 years of age—Use is not recommended .


If you overdose Generic Alafex and you don't feel good you should visit your doctor or health care provider immediately.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Detailed Fexofenadine/pseudoephedrine dosage information

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The most common side effects associated with Alafex are:

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Sixteen healthy volunteers underwent a double-blind within-subjects fMRI study investigating effects of placebo, 50 mg, and 200 mg pregabalin on neural activation during an emotional face-matching task. Given the great amount of free radicals which are constantly generated in the CNS, the discovery of a new enzyme with antioxidant properties which translocates into neuronal nuclei appears to be a potential starting point to develop alternative strategies in neuroprotection. Transient state isoelectric focusing: effects of zone load and carrier ampholyte concentration on the kinetics of defocusing and refocusing in sucrose density gradients. Here we show that proper localization of both formins requires the redundant E3 ubiquitin ligases Dma1 and Dma2, which were previously involved in spindle positioning and trileptal medication pregnancy septin organization. The -2518 A/G polymorphism in the monocyte chemoattractant protein 1 gene is associated with the risk of developing systemic lupus erythematosus in Argentinean patients: a multicenter study. A total of 140 acute lateral ankle ligament injuries in 132 patients (46 men, 86 women) treated non-operatively were evaluated retrospectively. The interval between apparent onset and diagnosis ranged from 3 months to 14 years. Effect of liver extracts, nicotinic acid and liver extracts with nicotinic acid on sulfur conjugation. Acute EtOH exposure can suppress tumor necrosis factor (TNF)-alpha production, which attenuates pulmonary defense against infection. Significantly reduced absolute as well as relative SHBG levels in comparison to all other groups were found in GH treated children.

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Choreic movement disorders result probably from diminished output from the basal ganglia, either from lesions of the subthalamic nucleus or from disordered regulation of subthalamic afferents. We have been putting a new focus on locomotive syndrome and frailty. Those patients with wrist fractures have the best prognosis in terms of mortality, whereas a proximal humerus fracture may indicate a higher risk of mortality. Observational data suggest that secondary preventative implantable cardioverter defibrillator therapy following resuscitated cardiac arrest prolongs the lives of dialysis patients. A case of a fatal pulmonary embolus after shoulder arthroplasty is reported. Some studies of the nature and clinical significance of porphobilinogen. A single baseline determination of the substance before digoxin is administered inadequately compensates for this interference, because the interferent concentrations can differ from day to day, with evidence that it may be most concentrated on the fourth to sixth postnatal day. The women were classified according to whether or not they had living children and, within that, whether they had experienced abortion, wanted more or any children or were pregnant. Spontaneous respiration recommenced 200 min after succinylcholine administration. bark: Protection against Liver Toxicity and Inflammation through Inhibiting Oxidative Stress and Proinflammatory Cytokines.

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In HRup rats, the H-reflex showed a large phase I increase within the first 2 days followed by gradual phase II increase that continued for weeks. Both H487F and H487L mutations abolished the enzymatic activity as well as the binding affinity for the cofactor FAD. It seems that technology-enhanced learning in a theoretical radiological science course has the potential to reduce the need for face-to-face lectures. The problem of precancer and three ways leading to malignancy are considered: induction of tumor precursors, accumulation of genetic traits common for tumor growth, and the role of inflammation in tumor induction. The association of 6MWD with measures of lower airway obstruction, and measures of adiposity was assessed. For the measurement to be calibrated, a model is required describing the kinetics of the flow of the inverted blood from the labeling region to the imaging region. A child with a right parieto-occipital astrocytoma, caped by a large acute pyogenic abscess with flimsy capsule, detected at emergency craniotomy, is presented. We show that free-solution electrophoresis problems can be seen as random walks in the conformational space of the analyte. The MOPDS was translated and validated for use in Chinese elders.

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Here, we introduce three light-sensitive DAGs, termed PhoDAGs, which feature a photoswitchable acyl chain. Nocturnal hypoxemia in OSA is an important predictor of poor prognosis for patients after MI. Presented here is a rare and first generic zantac recall 2020 such case of simultaneous presence of multiple supernumerary teeth and a missing tooth (canine) without any associated systemic conditions or syndromes involving both jaws. Climate change effects on water allocations with season dependent water rights. fuscipes in both treatments of direct exposure to elevated doses of Cry1C protein and prey-mediated exposure to realistic doses of the protein. Analysis of patterns and causes of artifacts found in endographic visualization of spiral CT data. Increasing the confidence in half-sibship determination based upon 15 STR loci. Cor triatriatum dextrum and persistent muscle of Lower, presenting as Budd-Chiari syndrome: embryology of a very rare disorder with unique morphologic, physiologic and clinical presentations. Thus, the impaired function of integrin beta 4-mediated adhesion is considered to be an important factor in intravasation during metastasis.

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