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Adiff (Adapalene)

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Adiff is used to treat acne. Adiff is in a class of medications called retinoid-like compounds. It works by stopping pimples from forming under the surface of the skin. Adiff has the unique ability to inhibit keratinocyte differentiation and decrease keratin deposition.

Other names for this medication:
Aclene, Acneril, Acneris, Acniriv, Acnovate, Adaferin, Adapalene, Adapen, Adaple, Adaret, Adgraze, Adiff, Adina, Aditop, Adlene, Alangel, Apalene, Apgel, Clinred, Daple, Deriva, Difra, Edplin, Faceclin, Labopene, Medapine, Rozac, Soflene, Vandep, Zolvee

Similar Products:
Cenforce, Indocin, Mysoline, Colcrys, Lipitor, Kemadrin, Moduretic, Chloromycetin, Axtrip, Neurowel, Nimkair, Valcort, Valcontin, Silagra,

Also known as: Adapalene


Adiff is a third-generation topical retinoid primarily used in the treatment of acne. Adiff is a gel used for the treatment of acne (blackheads, whiteheads and pimples) of the face, chest or back. Adiff gel is a clear gel that powers deep inside your pores to control the buildup that leads to acne. It helps prevent the formation of new acne lesions, and can also help get rid of lesions already present. Adiff works under the skin surface to unclog pores and clear up pimples. Adiff is also known as Adapalene, Adapen, Adaferin. Generic name of Adiff is Adapalene.


Usual Adult Dose for Acne:

Adiff 0.1% cream, 0.1% gel, 0.3% gel: Apply to the affected area once a day at bedtime after washing. A thin film should be applied, avoiding eyes, lips, angles of the nose, and mucous membranes. Lotion: Apply a thin film of lotion to the entire face and other affected areas of the skin once daily, after washing gently with a mild soapless cleanser. Dispense a nickel size amount of lotion (3 to 4 actuations of the pump) to cover the entire face. Avoid application to the areas of skin around eyes, lips and mucous membranes.

Usual Pediatric Dose for Acne:

Adiff 0.1% cream, 0.1% gel, 0.3% gel: 11 years or less: Safety and efficacy have not been established. 12 to 18 years: Apply to the affected area once a day at bedtime after washing. A thin film should be applied, avoiding eyes, lips, angles of the nose, and mucous membranes. Safety and effectiveness of the lotion formulation in pediatric patients under the age of 12 have not been established.

Detailed Adiff dosage information


Seek emergency medical attention if you think you have used too much of this medicine. Overdose symptoms may include skin redness, scaling, or irritation.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Detailed Adiff dosage information

Side effects

The most common side effects associated with Adiff are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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Data from the NEEAR study, which evaluated swimming and wading in marine and freshwater beaches in six U.S. Recent advancements in molecular and genomic studies have provided valuable tools and resources for comprehensive and high-resolution analysis of epigenomes during cell specification and lineage differentiation throughout development. In addition, strictly monotonically decreasing steady-state autocorrelation functions that decay faster than exponential functions are found, which are used to describe the erratic motion of the center of pressure during quiet standing. Organization of hyperactive microglial cells in trigeminal spinal subnucleus caudalis and upper cervical spinal cord associated with orofacial neuropathic pain. To make this technique more suitable for clinical applications, the possibility of using a standard diagnostic x-ray tube generating a continuous spectrum was investigated in this paper. We evaluated the efficacy of dexamethasone added to ramosetron, which is a newly developed five-hydroxytryptamine receptor 3 antagonist with a higher receptor affinity and longer action duration compared to its congeners, on preventing PONV in highly susceptible patients receiving opioid-based IV PCA after spinal surgery. EI from a meal with an unknown ED can become inversely related to EI through learning or conditioning. Elicitation of experimental allergic encephalomyelitis (EAE) in mice with the aid of pertussigen. The mutation of AP-2 binding motifs LL164 and DD174 in Nef leads to the inhibition of Ii chain upregulation.

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Retrospective chart review from 2006 through 2014 in a hospital-based dental clinic for permanent tooth pre-fabricated crown longevity. Connections between groundwater flow and transpiration partitioning. On the other hand, microecosystems may be applied usefully for the evaluation of ambient environmental quality criteria, provided that the design is suitable for replicable long-term continuous exposure experiments. In addition to localized areas of erythematosus induration, the patient demonstrated yellowish papules on her legs. During the acetylcholinesterase catalytic process, the acetylcholine substrate attaches to the peripheral anionic site and then slides to the catalytic site situated in the center of the enzyme, at the bottom of a deep and narrow active gorge.

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Dr Barbara Lewis of the University of Manchester Institute of Science and Technology describes her own survey in which she investigated how attitudes to organ donorship have changed in recent years and whether blood donors feel differently to the general public. Bone-marrow preparations were made and slides scored for the presence of micronuclei in the developing erythrocytes. The purpose of the present study was to evaluate how the symptom intensity reported by the patient relates to the time of the year in a temperate climate, i.e. The re-solubilized antibody was indistinguishable in structure, solubility and monodispersity from the unstressed protein. The presentation addresses both factors that have impeded and those that have facilitated landmark advances on the pathophysiology and treatment of bipolar disorders. : This survey suggests that the majority of urogynecologists attending the 34th SGS annual scientific meeting have used vaginal mesh for prolapse repair, and they more commonly used it in the anterior as compared to the posterior compartment. CASE RECORDS of the Massachusetts General Hospital Weekly Clinicopathological Exercises: Case 40092. In a retrospective review, the authors describe the pros and cons of the main treatment modalities that have been described in literature and present their own clinical experience.

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