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Adapalene is used to treat acne. Adapalene is in a class of medications called retinoid-like compounds. It works by stopping pimples from forming under the surface of the skin. Adapalene has the unique ability to inhibit keratinocyte differentiation and decrease keratin deposition.

Other names for this medication:
Aclene, Acneril, Acneris, Acniriv, Acnovate, Adaferin, Adapalene, Adapen, Adaple, Adaret, Adgraze, Adiff, Adina, Aditop, Adlene, Alangel, Apalene, Apgel, Clinred, Daple, Deriva, Difra, Edplin, Faceclin, Labopene, Medapine, Rozac, Soflene, Vandep, Zolvee

Similar Products:
Chloromycetin, Minipress, Uroxatral, Desyrel, Aldactone, Buspar, Levlen, Symbicort, Linzid, Kinzalkomb, Oncomide, Citalent, Bisolol, Regulate, Diclosef,


Adapalene (adapalene) is a topical medicine (a medication that is applied to the surface of the skin) similar to vitamin A. It helps the skin to renew itself.

Adapalene is used to treat severe acne in people who are at least 12 years old. It works by decreasing acne formation.


Usual Adult Dose for Acne:

Adapalene 0.1% cream, 0.1% gel, 0.3% gel: Apply to the affected area once a day at bedtime after washing. A thin film should be applied, avoiding eyes, lips, angles of the nose, and mucous membranes. Lotion: Apply a thin film of lotion to the entire face and other affected areas of the skin once daily, after washing gently with a mild soapless cleanser. Dispense a nickel size amount of lotion (3 to 4 actuations of the pump) to cover the entire face. Avoid application to the areas of skin around eyes, lips and mucous membranes.

Usual Pediatric Dose for Acne:

Adapalene 0.1% cream, 0.1% gel, 0.3% gel: 11 years or less: Safety and efficacy have not been established. 12 to 18 years: Apply to the affected area once a day at bedtime after washing. A thin film should be applied, avoiding eyes, lips, angles of the nose, and mucous membranes. Safety and effectiveness of the lotion formulation in pediatric patients under the age of 12 have not been established.

Detailed Adapalene dosage information


If you overdose Adapalene and you don't feel good you should visit your doctor or health care provider immediately.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Detailed Adapalene dosage information

Side effects

The most common side effects associated with Adapalene are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

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