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Acyclor (Acyclovir)
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Acyclor

Acyclor is approved by the Food and Drug Administration as a prescription drug that is commonly used as a topical, injectable, and oral treatment for genital herpes and cold sores. Herpes viral infections are very common. Genital herpes refers to a sexually transmitted disease (STD).

Other names for this medication:
Accrivir, Aciherpin, Acirax, Acloriv, Acvirall, Acycloguanosine, Acyclor, Acylab, Alovir, Civir, Cloviderm, Clovir, Clovirax, Clyvir, Cycloex, Cyclopiz, Docvir, Herpex, Herpovir, Herzovir, Lovir, Lyrovir, Ocurax, Ocuvir, Ophtrhovir, Optiviral, Oveer, Psyvir, Ridoherp, Rivol, Rovir, Setuvir, Spaclovir, Virex, Viroderm, Viroxit, Vivorax, Zovir, Zoylex

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Also known as: Acyclovir

Description

Acyclovir belongs to the family of medicines called antivirals, which are used to treat infections caused by viruses. Usually these medicines work for only one kind or group of virus infections.

Acyclovir is used to treat the symptoms of chickenpox, shingles, herpes virus infections of the genitals (sex organs), the skin, the brain, and mucous membranes (lips and mouth), and widespread herpes virus infections in newborns. Acyclovir is also used to prevent recurrent genital herpes infections. Although acyclovir will not cure herpes, it does help relieve the pain and discomfort and helps the sores (if any) heal faster.

Acyclovir may also be used for other virus infections as determined by your doctor. However, it does not work in treating certain virus infections, such as the common cold.

Acyclovir is available only with your doctor's prescription.

Dosage

Patient information about the treatment of herpes, chickenpox, or shingles is available with this medicine. Read it carefully before using this medicine.

Acyclovir is best used as soon as possible after the symptoms of herpes infection or shingles (for example, pain, burning, blisters) begin to appear.

If you are taking acyclovir for the treatment of chickenpox, it is best to start taking acyclovir as soon as possible after the first sign of the chickenpox rash, usually within one day.

Acyclovir capsules, tablets, and oral suspension may be taken with meals or on an empty stomach.

Acyclovir is best taken with a full glass (8 ounces) of water.

If you are using acyclovir oral suspension, use a specially marked measuring spoon or other device to measure each dose accurately. The average household teaspoon may not hold the right amount of liquid.

To help clear up your herpes infection, chickenpox, or shingles, keep taking acyclovir for the full time of treatment, even if your symptoms begin to clear up after a few days. Do not miss any doses. However, do not use this medicine more often or for a longer time than your doctor ordered.

If you are taking acyclovir capsules, tablets, or oral suspension, you should drink plenty of water to avoid becoming dehydrated.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage forms (capsules, oral suspension, or tablets): For treatment of genital herpes: Adults and children 12 years of age and older—200 milligrams (mg) five times a day for ten days. Children up to 12 years of age—Use and dose must be determined by the doctor. For prevention of recurrent outbreaks of genital herpes infections: Adults and children 12 years of age and older—200 to 400 mg two to five times a day for five days or up to twelve months, depending on how often your outbreaks of infection occur. Children up to 12 years of age—Use and dose must be determined by the doctor. For treatment of chickenpox: Adults and children who weigh over 88 pounds (40 kilograms)—800 mg four times a day for five days. Children 2 years of age and older and weighing 88 pounds (40 kilograms) or less—Dose is based on body weight and must be determined by the doctor. The usual dose is 20 mg per kilogram (kg) of body weight, up to 800 mg, four times a day for five days. Children up to 2 years of age—Use and dose must be determined by the doctor. For treatment of shingles: Adults and children 12 years of age and older—800 mg five times a day for seven to ten days. Children up to 12 years of age—Use and dose must be determined by the doctor. For injection dosage form: For treatment of herpes of the brain, genitals, or mucous membranes, or for the treatment of shingles: Adults and children 12 years of age and older—Dose is based on body weight and must be determined by the doctor. The usual dose is 5 to 10 mg of acyclovir per kg (2.3 to 4.5 mg per pound) of body weight, injected slowly into a vein over at least a one-hour period, and repeated every eight hours for five to ten days. Children up to 12 years of age—Dose is based on body weight and must be determined by the doctor. The usual dose is 10 mg to 20 mg of acyclovir per kg (4.5 mg to 9.1 mg per pound) of body weight, injected slowly into a vein over at least a one-hour period and repeated every eight hours for seven to ten days. For treatment of widespread herpes virus infection in newborns: Infants from birth to 3 months of age—Dose is based on body weight and must be determined by the doctor. The usual dose is 10 mg of acyclovir per kg (4.5 mg per pound) of body weight, injected slowly into a vein over at least a one-hour period and repeated every eight hours for ten days.

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Detailed Acyclor dosage information

Side effects

The most common side effects associated with Acyclor are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not take Acyclor if you are allergic to acyclovir or valacyclovir (Valtrex).

To make sure Acyclor is safe for you, tell your doctor if you have:

kidney disease; or a weak immune system (caused by disease or by using certain medicine).

Tell your doctor if you are pregnant or breastfeeding.

Herpes can be passed to your baby during childbirth if you have a genital lesion when your baby is born. If you have genital herpes, it is very important to prevent herpes lesions during pregnancy. Take your medicine as directed to best control your infection.

It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.

Acyclor should not be given to a child younger than 2 years old.

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Although viral hepatitis is one of the most frequent causes of FHF, the use of viral agents to develop animal models has been little and unfortunate. In addition, methylation analyses indicated that tissue-specific CpG methylation of the Pde4d promoter was correlated with Pde4d mRNA expression in major E15.5 tissues. Involvement of phosphatidylinositol 3-kinase/Akt on basic fibroblast growth factor-induced glial cell line-derived neurotrophic factor release from rat glioma cells. T helper1/t helper2 cells and resistance/susceptibility to leishmania infection: is this paradigm still relevant?. Group C streptococci isolated lipitor 40 mg side effects from throat swabs: a laboratory and clinical study. Fasciola hepatica as a cause of jaundice after chewing khat: a case report. Characterization of outward potassium current in embryonic chick heart cells. This review will focus and summarize the potential of this subset in cell-based treatments of human transplantation and highlight major discovery in the last months. Role of the equilibrative and concentrative nucleoside transporters in the intestinal absorption of the nucleoside drug, ribavirin, in wild-type and Ent1(-/-) mice. The complete PDB was converted into a database comprising almost 300,000 optimized fingerprints of local binding sites together with their associated ligand fragments.

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