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Actrim (Trimethoprim)

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This medication is a combination of two antibiotics: sulfamethoxazole and trimethoprim. It is used to treat a wide variety of bacterial infections. It is used to treat a wide variety of bacterial infections (such as middle ear, urine, respiratory, and intestinal infections). It is also used to prevent and treat a certain type of pneumonia (pneumocystis-type). This medication treats only certain types of infections. It will not work for viral infections (such as flu). Unnecessary use or misuse of any antibiotic can lead to its decreased effectiveness.

Other names for this medication:
Assepium, Astrim, Bactekod, Bactramin, Bactricid, Bactricida, Balkatrin, Bascul, Broncoflam, Cotribene, Deprim, Dientrin, Diseptyl, Ditrim, Dotrim, Drylin, Editrim, Eliprim, Forcrim, Gentrim, Infectrin, Kaftrim, Kemoprim, Kombitrim, Lupectrin, Nopil, Novidrine, Noxaprim, Oriprim, Primazol, Primazole, Purbac, Qiftrim, Regtin, Septrin, Sigaprim, Sinersul, Spectrem, Sulfatrim, Suprasulf, Supreme, Terbosulfa, Trimecor, Trimetoger, Trimoks, Trimol, Trimoxsul, Trisolvat, Tritenk

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Also known as: Trimethoprim


Sulfamethoxazole and trimethoprim combination is used to treat infections including urinary tract infections, middle ear infections (otitis media), bronchitis, traveler's diarrhea, and shigellosis (bacillary dysentery). This medicine is also used to prevent or treat Pneumocystis jiroveci pneumonia or Pneumocystis carinii pneumonia (PCP), a very serious kind of pneumonia. This type of pneumonia occurs more commonly in patients whose immune systems are not working normally, including cancer patients, transplant patients, and patients with acquired immune deficiency syndrome (AIDS).

Sulfamethoxazole and trimethoprim combination is an antibiotic. It works by eliminating the bacteria that cause many kinds of infections. This medicine will not work for colds, flu, or other virus infections.

This medicine is available only with your doctor's prescription.


Take this medication by mouth, as directed by your doctor, with a full glass of water (8 ounces / 240 milliliters). If stomach upset occurs, take with food or milk. Drink plenty of fluids while taking this medication to lower the unlikely risk of kidney stones forming, unless your doctor advises you otherwise. Dosage is based on your medical condition and response to treatment. Antibiotics work best when the amount of medicine in your body is kept at a constant level. Therefore, take this drug at evenly spaced intervals. Continue to take this medication until the full prescribed amount is finished, even if symptoms disappear after a few days. Stopping it too early may allow bacteria to continue to grow, which may result in a relapse of the infection. Tell your doctor if your condition persists or worsens.


Often, no treatment is needed for an antibiotic overdose. Usually, you'll need to watch for stomach upset and possibly diarrhea. In those cases, you should give extra fluids.


Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

Side effects

The most common side effects associated with Actrim are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of sulfamethoxazole and trimethoprim combination in children 2 months of age and older. Because of the toxicity of the combination of sulfamethoxazole and trimethoprim, use in infants younger than 2 months of age is not recommended.

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Time studies are reported on different numbers of technicians and different rotational assignment alternatives. Gastrointestinal bleeding in patients with acute spinal injuries. High uptake efficiency and no cytotoxic effects indicate graphene quantum dots can be suitable for bio-targeting. Nonetheless, toxicity from these therapies should be considered carefully because most of patients might present with kidney dysfunction that could limit the use of some agents. An angle-supported foldable phakic intraocular lens for correction of myopia: A five-year follow-up. These findings revealed working memory (updating and maintenance) and executive control declines in the T2DM compared to healthy older controls but smaller than that suffered by the AD patients. Impetigo is a highly contagious, superficial skin disease that is frequently seen in children. Renal function and histology after long-term vitamin D therapy of vitamin D refractory rickets.

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Influence of protein intake on magnesium requirement during protein synthesis. The classical secretion of soluble proteins and transport of integral membrane proteins to the cell surface require transit into and through the endoplasmic reticulum and the Golgi apparatus. caprae showed more stage IV granulomas, more MNGCs and higher AFBs counts than those induced by M. Although it is well recognized that people with multiple sclerosis (MS) may experience impairments in addition to limited mobility, there has been little effort to study their relative importance to patients with the condition. The field of phylogeography has long since realized the need and utility of incorporating nuclear DNA (nDNA) sequences into analyses. The authors compared the use of antibiotics and other medicines between the two groups of parents. Orthostatic hypotension may complicate very-low-calorie protein diets because of sodium depletion and depressed sympathetic nervous system activity. Prospective multi-center registry to evaluate efficacy and safety of the newly developed diamond-like carbon-coated cobalt-chromium coronary stent system. RESEARCH ON INTESTINAL FIXATION OF VITAMIN B-12 IN THE ABSENCE OF INTRINSIC FACTOR. Subsequent experiments examined the long-term effect of changing diets.

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